Top 50 Mental Health startups in USA

May 03, 2026
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1
Jimini Health
Funding: $25M
Jimini Health develops AI-assisted solutions for behavioral health care, focusing on continuous patient support between clinical sessions.
2
Grow Therapy
Funding: $328M
Grow Therapy helps therapists easily start and grow thriving insurance-accepting practices, giving them the administrative and business tools, peer community support, and pipeline of referrals they need to make their lives better.
3
Click Therapeutics
Funding: $1.1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
4
Lyra Health
Funding: $910.1M
Lyra is transforming mental health care by creating a frictionless experience for members, providers, and employers. Using technology and data, we connect companies and their employees to mental health providers and treatments that work.
5
Cerebral
Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
6
Spring Health
Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
7
Talkiatry
Funding: $452M
Talkiatry is a virtual mental health care platform with over 800 full-time psychiatrists. These specialists provide care for a variety of conditions, including anxiety, depression, insomnia, mood disorders, postpartum depression, pediatric mental health, bipolar disorder, OCD, PTSD and substance use disorders. Their work is powered by AI platform that facilitates interaction with patients between visits and monitors the quality and level of care provided. The startup also implements innovative payment models with insurance companies.
8
Neuronetics
Funding: $451.4M
Neuronetics has pioneered and refined the NeuroStar TMS Therapy system. This non-invasive, non-systemic treatment for depression uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions. NeuroStar TMS Therapy is a safe and effective outpatient procedure, performed in a physician's office with each treatment lasting about 37 minutes daily for four to six weeks.
9
Talkspace
Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
10
Headway
Funding: $325.5M
Headway is building a new mental healthcare system that everyone can access.
11
Quartet Health
Funding: $270.9M
Quartet is a technology company improving behavioral health delivery for patients, providers, and payers.
12
Alma
Funding: $220.5M
Alma is a membership-based network for mental health care providers.
13
Brightline
Funding: $219M
Brightline is a med-tech company that provides behavioral healthcare services for children and their families.
14
Calm
Funding: $218M
Calm is working to bring the amazing benefits of meditation to a busy world. Calm operates an online portal which allows busy and information loaded web workers to reduce stress.
15
Cognito Therapeutics
Funding: $216.8M
Cognito is developing a therapeutic device, Spectris, which can be prescribed by doctors and used by patients at home to treat Alzheimer's disease by stimulating coordinated neural activity through non-invasive visual and auditory stimulation. The device is designed as a full-size headphones. The pivotal clinical study, which is evaluating Spectris AD therapy for Alzheimer's disease, is currently underway, and the company is preparing to submit an application to the FDA.
16
Lark Health
Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
17
SonderMind
Funding: $183M
SonderMind Wellness Centers is a franchisor of community centers for behavioral health providers.
18
Modern Health
Funding: $167.4M
Modern Health is a mental well-being platform for innovative companies that want to reduce burnout and prevent turnover.
19
Big Health
Funding: $135.1M
Big Health operates a digital healthcare portal used to offer behavioral programs for mental health issues.
20
Eleos Health
Funding: $128M
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
21
Eleos
Funding: $128M
Eleos Health is a mental health startup that focuses on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
22
Woebot Health
Funding: $123.3M
Woebot Health offers digital therapeutics to make mental health radically accessible.
23
Happify Health
Funding: $118.7M
Happify is a software-enabled health care platform designed to improve mental and physical health.
24
Valera Health
Funding: $115M
Valera Health is a tech-enabled mental health company delivering inclusive, comprehensive and tailored care.
25
Author Health
Funding: $115M
Author Health provides care and treatment for Medicare Advantage recipients with substance use disorders and serious mental illness.
26
Brightside Health
Funding: $114.4M
Brightside Health is a telemedicine platform integrating precision psychiatry with advanced therapeutic techniques.
27
Two Chairs
Funding: $102M
Two Chairs is rebuilding the nation's mental health system. With expert clinicians, thoughtful technology, and user-centric design they’re making exceptional mental healthcare available to everyone.
28
Octave
Funding: $91M
Octave offers a modern practice that brings a primary care approach to serve the mental health needs of young urban professionals.
29
NOCD
Funding: $84M
nOCD offers a mobile mental health app. Our goal is to revolutionize OCD treatment.
30
eNeura
Funding: $75.8M
eNeura, a privately held medical technology company, is pioneering the use of portable, non-invasive Transcranial Magnetic Stimulation (TMS) devices for treatment of migraine. Prescribed by physicians but designed for patient use, it is the first truly portable, convenient TMS product that will allow migraine patients to administer treatment as needed—at home, in the office or on the go.
31
Tava Health
Funding: $73M
Tava Health is a hybrid platform for mental health services. It partners with employers, individuals and insurance companies, offering online and in-person consultations with psychologists, both in-network and for cash. It enables companies to offer employee benefits, including sponsored therapy at no additional cost or a model that leverages the employee's existing insurance with no additional employer fees. The company's AI algorithm matches each patient with licensed therapists. The company is also provides free practice management platform for behavioral health professionals, integrating an AI-powered clinical secretary, treatment planning, scheduling tools and telemedicine module, and provides payment from over 200 insurance companies within two weeks with chargeback protection.
32
aptihealth
Funding: $65M
Aptihealth specializes in behavioral health, health plans, primary care, therapy, direct messaging and medication management services.
33
NeuroFlow
Funding: $60.6M
NeuroFlow is a HIPAA-compliant cloud-based platform that empowers health care providers to objectively track, assess, and engage patients using evidence-based practices to support their mental health.
34
Concert Health
Funding: $58.5M
Concert Health offers behavioral health services to primary care practices
35
Folx Health
Funding: $59.4M
Folx Health is a telehealth platform that provides digital healthcare services designed for the LGBTQIA+ community.
36
Osmind
Funding: $57.2M
Osmind is the premier technology platform for breakthough mental health treatment and research.
37
Rippl
Funding: $55M
Rippl, a mental health organization, is committed to assisting seniors who suffer from dementia and other neurocognitive disorders.
38
Meru Health
Funding: $53.3M
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
39
Real 
Funding: $53M
Real is making mental wellness an essential part of wellbeing.
40
Brave Health
Funding: $50M
Brave Health is an online platform that offers therapy and medication management for psychiatric conditions to improve mental health.
41
Array Behavioral Care
Funding: $49M
Array Behavioral Care telepsychiatry service provider with a mission to transform access to quality and timely behavioral health care.
42
BrainCheck
Funding: $41.2M
BrainCheck is a mobile interactive test for cognitive health.
43
Sonde Health
Funding: $41.3M
Sonde Health has developed a technology that uses voice biomarkers to identify a number of diseases such as respiratory disorders and mental illness.
44
Iris Telehealth
Funding: $40M
Iris Telehealth is a leading provider of telepsychiatry services for community mental health centers, community health centers.
45
Nirvana Health
Funding: $39.4M
Nirvana Health is a mental health company providing modern fintech and insurance solutions to healthchare.
46
Uwill
Funding: $38.5M
Uwill with colleges to offer students on-demand virtual access to licensed therapists and providers trained in crisis counseling. Students can also attend online wellness events through the company's mental health-and-wellness app.
47
Little Otter
Funding: $35.7M
Little Otter is a children's mental health company that developed an app that focuses on the mental health of children and their families.
48
Mantra Health
Funding: $34.2M
Mantra Health is a digital mental healthcare company designed for all university students.
49
Blueprint
Funding: $32.3M
Blueprint aids mental health clinicians in providing personalized results through measurement-based care.
50
Kintsugi
Funding: $30.9M
Kintsugi is a smart voice journaling platform for mental health. We use voice biomarkers to measure and predict well-being.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com