Top 10 Immunology startups

Updated: April 17, 2024

These startups are at the forefront of developing cutting-edge technologies, such as gene editing techniques, monoclonal antibodies, and immune modulators, to advance precision medicine and revolutionize the treatment of autoimmune disorders by enhancing immune system function, targeting specific disease pathways, and improving patient outcomes.
1
Country: USA | Funding: $526.3M
Viela Bio is a clinical-stage biotechnology company pioneering and advancing treatments for severe inflammation and autoimmune diseases.
2
Country: USA | Funding: $509M
Annexon Biosciences a biotechnology company, discovers and developing novel therapeutics for neurodegenerative and autoimmune disorders.
3
Country: USA | Funding: $499.8M
Atara Biotherapeutics is a leading off-the-shelf, allogeneic T-cell immunotherapy company developing novel treatments for patients with cancer, autoimmune and viral diseases, multiple sclerosis (MS).
4
Country: USA | Funding: $487M
Odyssey Therapeutics is a computational immunology company that develops novel therapeutics for patients with autoimmune diseases.
5
Country: USA | Funding: $400M
Celgene spinout that aims is to develop cells from placentas against blood cancers and is founded on the use of stem cells from placentas. The goal is to create therapies across autoimmune and degenerative disease, immuno-oncology, and functional regeneration.
6
Country: USA | Funding: $397M
Evelo is pioneering therapies that modulate systemic immune response by acting on the gut-body network - monoclonal microbials. They have the potential to treat many diseases, including inflammatory disease, cancer, autoimmune disease, metabolic, neurobehavior and neuroinflammatory diseases.
7
Country: Germany | Funding: $250M
GEMoaB develops universal CAR-T platform with focus on providing significantly safer and more efficacious treatments to patients who are suffering from hard-to-treat cancers and autoimmune diseases
8
Country: USA | Funding: $227M
Shattuck Labs is a biotechnology company that provides novel class biologic medicines for the treatment of cancer and autoimmune disease.
9
Country: USA | Funding: $222M
Seismic Therapeutic is a biotechnology company advancing machine learning for immunology drug development.
10
Country: USA | Funding: $214.8M
Abcuro develops first-in-class immunotherapies to treat autoimmunity and cancer.
11
Country: USA | Funding: $210M
Cabaletta Bio has adapted clinically-validated and FDA-approved CAR T cell technology to target B cell-mediated autoimmune diseases.
12
Country: USA | Funding: $199M
ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.
13
Country: China | Funding: $195M
Connect Biopharmaceuticals is a developer of novel immune modulators for the treatment of serious autoimmune diseases and inflammation.
14
Country: USA | Funding: $183M
Sudo Biosciences is a biopharmaceutical company committed to developing cutting-edge medications that are unmatched in their class that advances programs in multiple sclerosis and psoriasis
15
Country: USA | Funding: $182M
Be Biopharma engineers B-cell therapies. The applications of B cells include everything from autoimmune diseases to cancer and monogenic disorders, which are caused by variation in a single gene.
16
Country: France | Funding: $179.5M
HiFiBiO Therapeutics is biotherapeutics company mobilizing the human immune system to combat disease. We integrate deep-rooted biological expertise with our comprehensive single-cell profiling technologies to rapidly discover and advance a pipeline of antibody drugs to treat cancer and autoimmune disorders. We also aspire to benefit patients through open-innovation partnerships with industry and academia.
17
Country: USA | Funding: $177M
GentiBio is a biotherapeutics company developing engineered regulatory T cells (EngTregs) programmed to treat autoimmune allergic diseases.
18
Country: USA | Funding: $133.8M
Navidea Biopharmaceuticals has established a niche in precision medicine. The company focuses on the development and commercialization of diagnostic agents and therapeutics for cancer, autoimmune diseases, dementia, and movement disorders.
19
Country: Israel | Funding: $101.5M
KAHR Medical develops novel fusion protein pharmaceuticals for the treatment of cancer and autoimmune diseases.
20
Country: USA | Funding: $70M
Landos Biopharma is a developer of an oral first-in-class therapeutics designed to target autoimmune diseases.
21
Country: USA | Funding: $50M
Cimeio Therapeutics is applied gene editing, cellular and immunotherapy company, developing shielded-cell and immunotherapy pairs to transform treatment for rare genetic diseases, hematologic malignancies and autoimmune disorders.
22
Country: USA | Funding: $50M
Metaphore Biotechnologies is a firm that uses biomimicry and machine learning to unlock the revolutionary therapeutic. The company aims the platform at developing treatments for autoimmune, metabolic and oncology indications.
23
Country: France | Funding: €40M
Egle Therapeutics is a biotechnology company focused on developing immunotherapies for oncology and autoimmune diseases.
24
Country: China | Funding: $15M
META Pharmaceuticals is a cutting-edge drug development company specializing in autoimmune diseases.
25
Country: USA
Alumis is a precision medicines company that is transforming the lives of patients living with immune-mediated diseases using a precision approach to develop oral therapies.