Top 10 Rheumatoid Arthritis treatment startups

Updated: Jun 24, 2026
|
These startups develop new Rheumatoid Arthritis treatments and diagnostics technologies, like immunotherapy, drug-delivery implants, genome analyses, AI drug discovery.
1
Nimbus Therapeutics
Country: USA | Funding: $637M
Nimbus Therapeutics develops highly selective and potent small molecule drugs aimed at suppressing known factors that cause serious diseases, including metabolic diseases, cancer, and immune-inflammatory disorders (psoriasis, arthritis). The company's drug discovery platform utilizes advanced protein structure analysis, molecular modeling, machine learning-based prediction, and comprehensive data analysis within a target-oriented approach. The atomic-level data obtained using these tools enables the creation of highly accurate molecules that determine optimal pharmacological profiles for the treatment of disease pathology.
2
Acelyrin
Country: USA | Funding: $558M
ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing inflammatory-disease-focused therapies.
3
SetPoint Medical
Country: USA | Funding: $496.4M
SetPoint Medical treats patients with debilitating inflammatory diseases using proprietary implantable bioelectronic devices.
4
Evelo Biosciences
Country: USA | Funding: $397M
Evelo is pioneering therapies that modulate systemic immune response by acting on the gut-body network - monoclonal microbials. They have the potential to treat many diseases, including inflammatory disease, cancer, autoimmune disease, metabolic, neurobehavior and neuroinflammatory diseases.
5
AltruBio
Country: USA | Funding: $327.6M
AltruBio develops antibody-targeted therapies for psoriatic arthritis and ulcerative colitis
6
MiroBio
Country: UK | Funding: $130M
MiroBio develops novel, best-in-class therapeutics that bring significant benefits to patients suffering from a range of auto-immune diseases. MiroBio's medicines will activate natural mechanisms to regain control of over-active immune responses triggering these diseases.
7
Elevara
Country: UK | Funding: $70M
Elevara is a clinical-stage firm working on innovative therapies to treat rheumatoid arthritis and other chronic inflammatory disorders.
8
Joint Academy
Country: Sweden | Funding: $33.2M
Joint Academy is a digital clinic that provides digital treatment for patients with osteoarthritis and chronic joint pain.
9
DNAlytics
Country: Belgium | Funding: €50K
DNAlytics develops revolutionary disease diagnostic processes that complement conventional methods. Their main product is RheumaKit, a test that analyzes biological and clinical data to identify and treat arthritis disease.
10
Digital Rheuma Lab
Country: Germany
Digital Rheuma Lab is building digital solutions in Rheumatology
  See also:
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com