Top 20 AI startups in Healthcare in USA

Dec 23, 2025
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1
Tempus
Funding: $2.3B
Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.
2
Freenome
Funding: $1.5B
Freenome is a platform that helps design healthy conditions for an individual based on his/her cell-free genome. It employs Artificial Intelligence to detect colorectal cancer.
3
Abridge
Funding: $757.5M
Abridge is a medical conversation AI startup that offers an audio-based system to record and summarize medical conversations.
4
insitro
Funding: $743M
Insitro is a machine-learning driven drug discovery and development company.
5
Lila Sciences
Funding: $550M
Lila Sciences creates a scientific superintelligence platform and autonomous labs for life sciences, chemistry, and materials science.
6
Spring Health
Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
7
Metagenomi
Funding: $457M
Metagenomi is using the power of metagenomics and machine learning to discover novel genome editing systems.
8
Hippocratic AI
Funding: $402M
Hippocratic AI’s Aim is to develop the safest artificial Health General Intelligence (HGI).
9
Absci
Funding: $394.3M
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
10
Caresyntax
Funding: $387.5M
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
11
PathAI
Funding: $355.2M
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
12
Clarify Health Solutions
Funding: $328M
Clarify Health Solutions develops analytics and software solutions that enable health systems to deliver more satisfying, better outcome and higher value care
13
Ambience Healthcare
Funding: $319.3M
Ambience Healthcare is the leading AI operating system for healthcare organizations.
14
Iambic Therapeutics
Funding: $303M
Iambic Therapeutics is built on technologies for predicting protein-ligand structures, generating molecular designs and other drug discovery tasks. Using the technologies, Iambic claims it can accelerate drug discovery, pointing to the two years it took to take its lead project from program launch to IND to make its case.
15
ConcertAI
Funding: $300M
Concerto HealthAI is a global leader in real-world data, AI technology, and real-world evidence services for precision oncology and dedicated to engineering integrated data and technology solutions that help achieve the best possible outcomes for patients.
16
ConcertAI
Funding: $300M
ConcertAI, a real-world data and artificial intelligence startup for healthcare providers and life science companies
17
Immunai
Funding: $295M
Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.
18
Viz.ai
Funding: $291.6M
Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.
19
InterVenn Biosciences
Funding: $278.1M
InterVenn Biosciences combined the molecular-level resolution of mass spectrometry with the throughput of artificial intelligence to create a unique platform to discover new biomarkers, provide more effective treatments, design precision medicine trials, and pursue novel targets.
20
Genesis Therapeutics
Funding: $256.1M
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com