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Top 13 Gastroenterology startups in USA
Sep 29, 2025 | By Jason Kwon | 20 |
1
Funding: $1.2B
Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
2
Funding: $537.8M
Seres Therapeutics is creating a new class of medicines to treat diseases resulting from functional deficiencies in the microbiome, a condition known as dysbiosis
Seres Therapeutics is creating a new class of medicines to treat diseases resulting from functional deficiencies in the microbiome, a condition known as dysbiosis
3
Funding: $441.6M
Ventyx Biosciences develops a drug for inflammatory bowel disease
Ventyx Biosciences develops a drug for inflammatory bowel disease
4
Funding: $407.2M
Synergy is a gastrointestinal-focused biopharmaceutical company committed to science-based innovation, providing novel treatment options for patients and healthcare providers, rewarding opportunities for our employees, and creating exceptional value for our shareholders.
Synergy is a gastrointestinal-focused biopharmaceutical company committed to science-based innovation, providing novel treatment options for patients and healthcare providers, rewarding opportunities for our employees, and creating exceptional value for our shareholders.
5
Funding: $220.9M
Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
6
Funding: $119.5M
Oshi Health is a virtual-first medical practice revolutionizing the diagnosis, management and treatment of digestive health conditions.
Oshi Health is a virtual-first medical practice revolutionizing the diagnosis, management and treatment of digestive health conditions.
7
Funding: $105.6M
CapsoVision is a medical device company developing gastrointestinal medical devices.
CapsoVision is a medical device company developing gastrointestinal medical devices.
8
Funding: $58.8M
Vivante makes a digital program for digestive health and disease called GIThrive that includes, among other tools, a 24-7 support line to a gastrointestinal care team.
Vivante makes a digital program for digestive health and disease called GIThrive that includes, among other tools, a 24-7 support line to a gastrointestinal care team.
9
Funding: $19.5M
Salvo Health offers a virtual clinic geared toward people with chronic gut problems, including irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia and small intestinal bacterial overgrowth (SIBO).
Salvo Health offers a virtual clinic geared toward people with chronic gut problems, including irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia and small intestinal bacterial overgrowth (SIBO).
10
Funding: $6.4M
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
11
Funding: $2.2M
SmartTab is a digital medicine company which develops innovative wireless drug delivery and monitoring systems.
SmartTab is a digital medicine company which develops innovative wireless drug delivery and monitoring systems.
12
Funding: $1.6M
Kiwi Bio aims to free irritable bowel syndrome sufferers from restrictive diets. Kiwi’s product FODZYME uses patent-pending enzymes to break down common digestive triggers.
Kiwi Bio aims to free irritable bowel syndrome sufferers from restrictive diets. Kiwi’s product FODZYME uses patent-pending enzymes to break down common digestive triggers.
13
Casa de Sante is transforming gut health through convenient, personalized and virtual therapeutic care.
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