Top 48 Clinical trials startups

Updated: Dec 27, 2025
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These startups develop cloud and AI platforms that allow to optimize clinical trial process.
1
TrialSpark
Country: USA | Funding: $528M
TrialSpark is a technology company that helps bring treatments to patients faster by reimagining how clinical trials are run.
2
Medable
Country: USA | Funding: $506.6M
Medable's platform helps to facilitate the clinical trial process. Its mission is to reduce clinical trial timelines by 50%.
3
Reify Health
Country: USA | Funding: $479.6M
Reify Health is a cloud-based software company that develops tools for the clinical trial ecosystem.
4
Science 37
Country: USA | Funding: $347.5M
Science 37 is making the promise of virtual trials the new reality. By engaging with patients from the comfort of their own home, the company provides access to patients who can never be reached by traditional site-based research models.
5
Paradigm Health
Country: USA | Funding: $281M
Paradigm creates an intelligent platform that enables all patients to participate in clinical trials and helps biotech companies improve their efficiency. The platform uses AI to automate patient recruitment and evaluate the feasibility of conducting trials at sites. The system enables providers to visualize their entire research portfolio, identify opportunities for patients not yet enrolled in trials, analyze the effectiveness of their clinical trial portfolio compared to expected enrollment rates and automate the completion of electronic data collection forms. Paradigm specializes in oncology research, cardiovascular diseases, metabolic disorders and neuroscience.
6
4G Clinical
Country: USA | Funding: $252.1M
4G Clinical provides software and services for clinical drug trials specifically in randomization and trial supply management (RTSM).
7
Paradigm
Country: USA | Funding: $203M
Paradigm is building a platform that aims to streamline the clinical trial process for patients and connect biopharmaceutical trial sponsors and healthcare providers.
8
Elligo Health Research
Country: USA | Funding: $196M
Elligo Health Research is revolutionizing the clinical research industry with a novel approach to common trial challenges including patient participation and enrollment, and physician participation. They provide physicians and their patients the opportunity to participate in clinical trials using advanced health care informatics.
9
Unlearn.AI
Country: USA | Funding: $134.9M
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
10
Florence Healthcare
Country: USA | Funding: $115.8M
Florence advances clinical research through software by connecting trial sites with pharmaceutical sponsors.
11
Vial
Country: USA | Funding: $111M
Vial is a tech-enabled CRO delivering superior clinical trial outcomes.
12
Lindus Health
Country: UK | Funding: $79.5M
Lindus Health is a next-gen CRO running clinical trials for the health and biotech sectors.
13
AiCure
Country: USA | Funding: $68.8M
AiCure's mission is to equip patients, researchers and providers with the intelligence to understand the exact link between medication and health. By 2020, there will be 6 billion smartphones in use. AiCure is leveraging this technology by combining it with Artificial Intelligence to bring better health, better drugs, and better treatment to those who need it the most.
14
Teckro
Country: USA | Funding: $66M
Teckro is a life science technology company that is rethinking every element of clinical research.
15
PhaseV
Country: USA | Funding: $65M
PhaseV provides AI-driven solutions for efficient clinical development and operations.
16
Castor
Country: Netherlands | Funding: $64.4M
Castor offers a cloud-based clinical data platform that simplifies and streamlines clinical trials processes.
17
ObvioHealth
Country: Singapore | Funding: $61.9M
The company is focused on making clinical trials faster and more cost effective.
18
Curebase
Country: USA | Funding: $57.6M
Curebase is a provider of decentralized clinical research software solutions and services to patients and medical providers.
19
Thread
Country: USA | Funding: $50M
THREAD is a singular, fully configurable decentralized clinical trial platform with services that deliver global scalability and rapid flexibility from study design to close-out
20
SubjectWell
Country: USA | Funding: $46.8M
SubjectWell is the risk-free clinical trials marketplace for patient recruitment
21
uMotif
Country: UK | Funding: £28.7M
uMotif is a patient-facing clinical trial software company. Through simple and engaging web and mobile apps, people track and monitor their health and choose to share their data with their clinicians, carers, friends and family members to improve care.
22
Inato
Country: France | Funding: $35.5M
Inato allows sponsors and CROs to predict and tailor their recruitment strategy before the launch of clinical trials to reduce timelines.
23
Faro Health
Country: USA | Funding: $35M
Faro has developed software that allows rapid evaluation of clinical study costs, accessibility to patients and ease of study conduct
24
Lokavant
Country: USA | Funding: $29M
Lokavant is an IT firm that offers real-time visualizations, risk alerts, artificial intelligence, and human insight services.
25
TrialJectory
Country: USA | Funding: $27.7M
TrialJectory's mission is to use AI to transform the world of cancer care. By being the leading personalised, AI-based clinical trials data platform, the company partners with industry leaders to expedite new treatments into the market.
26
HealthMatch
Country: Australia | Funding: $27.5M
HealthMatch connects patients with revolutionary drugs and cures.
27
Topography Health
Country: USA | Funding: $27.5M
Topography focuses on creating a new topography of health.
28
VivoSense
Country: USA | Funding: $27M
VivoSense is an advancing clinical research with wearable sensor solutions.
29
Hawthorne Effect
Country: USA | Funding: $25.1M
Hawthorne Effect is a visit management system connecting sponsors, investigators & patients to make clinical trials accessible & convenient.
30
Mural Health
Country: USA | Funding: $20.7M
Mural Health is a firm that develops technology for clinical trials and is committed to making it simple for people to take part in studies.
31
CRIO
Country: USA | Funding: $19M
Clinical Research IO is a health tech company that offers paper-based clinical trials with software, eSource, CTMS, and eRegulatory.
32
Power
Country: USA | Funding: $18.9M
Power is a user-friendly tool made to make clinical trial research more accessible to patients.
33
QuantHealth
Country: Israel | Funding: $17M
Quant Health offers AI-based drug simulation, computational biology, clinical data science, respiratory, trial simulation, and oncology services.
34
ProofPilot
Country: USA | Funding: $15.7M
ProofPilot is a research company that specializes in the fields of public health, research, behavioral health, and market research.
35
Triomics
Country: USA | Funding: $15.1M
Triomics uses GenAI to help cancer centers streamline trial enrollments, quality improvement projects, and healthcare operations.
36
Panthera Biopartners
Country: UK | Funding: $13.1M
Panthera, an independent site management organisation run by a world-class team of experts, finds patients and runs clinical trials on behalf of CROs and pharma companies across multiple therapeutic areas.
37
Cohort
Country: USA | Funding: $11M
Cohort is a software to transform chronic care management and clinical trials.
38
ClinOne
Country: USA | Funding: $10.5M
ClinOne clinical trial management solution designed to access to mission-critical clinical trial details through web & mobile devices.
39
Research Grid
Country: UK | Funding: $8.1M
R.grid automates clinical trials with AI-driven platforms for efficiency.
40
Brooklyn Health
Country: USA | Funding: $6.5M
Brooklyn Health is a company of clinicians, scientists, and engineers dedicated to enhancing digital health measurement.
41
Trial Library
Country: USA | Funding: $5M
Trial Library is an oncology clinical trials company that uses AI to recruit and retain participants. It partners with global biopharmaceutical companies to accelerate research and development and enrollment.
42
Alleviate Health
Country: USA | Funding: $4.3M
Alleviate Health is an AI-enabled patient recruitment company for clinical trials
43
Jeeva Informatics
Country: USA | Funding: $2.1M
Jeeva's AI-driven cloud-based software provides a seamless solution that improves the experience of investigators and patients by decentralizing clinical trials.
44
Klineo
Country: France | Funding: €2M
Klineo is a platform that provides an intuitive and intelligent clinical trial search for oncology patients and doctors.
45
Evrima Technologies
Country: Australia | Funding: A$3M
Evrima has developed a suite of products and services to accelerate patient recruitment and trial management in phase I-IV clinical trials.
46
Hop Technologies
Country: Canada | Funding: $2M
Hop Technologies is increasing the efficiency of clinical trials and accelerating the creation of patient-centric treatments using our proprietary tailor-made algorithms generated from our existing end-to-end remote patient monitoring platform.
47
Clinion
Country: India
Clinion is a clinical trial solution, which is uniquely focused on delivering superior user experience.
48
Clinevo Technologies
Country: India
Clinevo Technologies is an IT Services & Software Development Company specialized in developing & implementing robust technology solutions.
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Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com