Top 34 Clinical trials startups in USA
Dec 27, 2025
|
Like
19
1
Funding: $528M
TrialSpark is a technology company that helps bring treatments to patients faster by reimagining how clinical trials are run.
TrialSpark is a technology company that helps bring treatments to patients faster by reimagining how clinical trials are run.
2
Funding: $506.6M
Medable's platform helps to facilitate the clinical trial process. Its mission is to reduce clinical trial timelines by 50%.
Medable's platform helps to facilitate the clinical trial process. Its mission is to reduce clinical trial timelines by 50%.
3
Funding: $479.6M
Reify Health is a cloud-based software company that develops tools for the clinical trial ecosystem.
Reify Health is a cloud-based software company that develops tools for the clinical trial ecosystem.
4
Funding: $347.5M
Science 37 is making the promise of virtual trials the new reality. By engaging with patients from the comfort of their own home, the company provides access to patients who can never be reached by traditional site-based research models.
Science 37 is making the promise of virtual trials the new reality. By engaging with patients from the comfort of their own home, the company provides access to patients who can never be reached by traditional site-based research models.
5
Funding: $281M
Paradigm creates an intelligent platform that enables all patients to participate in clinical trials and helps biotech companies improve their efficiency. The platform uses AI to automate patient recruitment and evaluate the feasibility of conducting trials at sites. The system enables providers to visualize their entire research portfolio, identify opportunities for patients not yet enrolled in trials, analyze the effectiveness of their clinical trial portfolio compared to expected enrollment rates and automate the completion of electronic data collection forms. Paradigm specializes in oncology research, cardiovascular diseases, metabolic disorders and neuroscience.
Paradigm creates an intelligent platform that enables all patients to participate in clinical trials and helps biotech companies improve their efficiency. The platform uses AI to automate patient recruitment and evaluate the feasibility of conducting trials at sites. The system enables providers to visualize their entire research portfolio, identify opportunities for patients not yet enrolled in trials, analyze the effectiveness of their clinical trial portfolio compared to expected enrollment rates and automate the completion of electronic data collection forms. Paradigm specializes in oncology research, cardiovascular diseases, metabolic disorders and neuroscience.
6
Funding: $252.1M
4G Clinical provides software and services for clinical drug trials specifically in randomization and trial supply management (RTSM).
4G Clinical provides software and services for clinical drug trials specifically in randomization and trial supply management (RTSM).
7
Funding: $203M
Paradigm is building a platform that aims to streamline the clinical trial process for patients and connect biopharmaceutical trial sponsors and healthcare providers.
Paradigm is building a platform that aims to streamline the clinical trial process for patients and connect biopharmaceutical trial sponsors and healthcare providers.
8
Funding: $196M
Elligo Health Research is revolutionizing the clinical research industry with a novel approach to common trial challenges including patient participation and enrollment, and physician participation. They provide physicians and their patients the opportunity to participate in clinical trials using advanced health care informatics.
Elligo Health Research is revolutionizing the clinical research industry with a novel approach to common trial challenges including patient participation and enrollment, and physician participation. They provide physicians and their patients the opportunity to participate in clinical trials using advanced health care informatics.
9
Funding: $134.9M
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
10
Funding: $115.8M
Florence advances clinical research through software by connecting trial sites with pharmaceutical sponsors.
Florence advances clinical research through software by connecting trial sites with pharmaceutical sponsors.
12
Funding: $68.8M
AiCure's mission is to equip patients, researchers and providers with the intelligence to understand the exact link between medication and health. By 2020, there will be 6 billion smartphones in use. AiCure is leveraging this technology by combining it with Artificial Intelligence to bring better health, better drugs, and better treatment to those who need it the most.
AiCure's mission is to equip patients, researchers and providers with the intelligence to understand the exact link between medication and health. By 2020, there will be 6 billion smartphones in use. AiCure is leveraging this technology by combining it with Artificial Intelligence to bring better health, better drugs, and better treatment to those who need it the most.
13
Funding: $66M
Teckro is a life science technology company that is rethinking every element of clinical research.
Teckro is a life science technology company that is rethinking every element of clinical research.
14
Funding: $65M
PhaseV provides AI-driven solutions for efficient clinical development and operations.
PhaseV provides AI-driven solutions for efficient clinical development and operations.
15
Funding: $57.6M
Curebase is a provider of decentralized clinical research software solutions and services to patients and medical providers.
Curebase is a provider of decentralized clinical research software solutions and services to patients and medical providers.
16
Funding: $50M
THREAD is a singular, fully configurable decentralized clinical trial platform with services that deliver global scalability and rapid flexibility from study design to close-out
THREAD is a singular, fully configurable decentralized clinical trial platform with services that deliver global scalability and rapid flexibility from study design to close-out
17
Funding: $46.8M
SubjectWell is the risk-free clinical trials marketplace for patient recruitment
SubjectWell is the risk-free clinical trials marketplace for patient recruitment
18
Funding: $35M
Faro has developed software that allows rapid evaluation of clinical study costs, accessibility to patients and ease of study conduct
Faro has developed software that allows rapid evaluation of clinical study costs, accessibility to patients and ease of study conduct
19
Funding: $29M
Lokavant is an IT firm that offers real-time visualizations, risk alerts, artificial intelligence, and human insight services.
Lokavant is an IT firm that offers real-time visualizations, risk alerts, artificial intelligence, and human insight services.
21
Funding: $27.7M
TrialJectory's mission is to use AI to transform the world of cancer care. By being the leading personalised, AI-based clinical trials data platform, the company partners with industry leaders to expedite new treatments into the market.
TrialJectory's mission is to use AI to transform the world of cancer care. By being the leading personalised, AI-based clinical trials data platform, the company partners with industry leaders to expedite new treatments into the market.
23
Funding: $25.1M
Hawthorne Effect is a visit management system connecting sponsors, investigators & patients to make clinical trials accessible & convenient.
Hawthorne Effect is a visit management system connecting sponsors, investigators & patients to make clinical trials accessible & convenient.
24
Funding: $20.7M
Mural Health is a firm that develops technology for clinical trials and is committed to making it simple for people to take part in studies.
Mural Health is a firm that develops technology for clinical trials and is committed to making it simple for people to take part in studies.
25
Funding: $18.9M
Power is a user-friendly tool made to make clinical trial research more accessible to patients.
Power is a user-friendly tool made to make clinical trial research more accessible to patients.
26
Funding: $19M
Clinical Research IO is a health tech company that offers paper-based clinical trials with software, eSource, CTMS, and eRegulatory.
Clinical Research IO is a health tech company that offers paper-based clinical trials with software, eSource, CTMS, and eRegulatory.
27
Funding: $15.7M
ProofPilot is a research company that specializes in the fields of public health, research, behavioral health, and market research.
ProofPilot is a research company that specializes in the fields of public health, research, behavioral health, and market research.
28
Funding: $15.1M
Triomics uses GenAI to help cancer centers streamline trial enrollments, quality improvement projects, and healthcare operations.
Triomics uses GenAI to help cancer centers streamline trial enrollments, quality improvement projects, and healthcare operations.
29
Funding: $10.5M
ClinOne clinical trial management solution designed to access to mission-critical clinical trial details through web & mobile devices.
ClinOne clinical trial management solution designed to access to mission-critical clinical trial details through web & mobile devices.
31
Funding: $6.5M
Brooklyn Health is a company of clinicians, scientists, and engineers dedicated to enhancing digital health measurement.
Brooklyn Health is a company of clinicians, scientists, and engineers dedicated to enhancing digital health measurement.
32
Funding: $5M
Trial Library is an oncology clinical trials company that uses AI to recruit and retain participants. It partners with global biopharmaceutical companies to accelerate research and development and enrollment.
Trial Library is an oncology clinical trials company that uses AI to recruit and retain participants. It partners with global biopharmaceutical companies to accelerate research and development and enrollment.
33
Funding: $4.3M
Alleviate Health is an AI-enabled patient recruitment company for clinical trials
Alleviate Health is an AI-enabled patient recruitment company for clinical trials
34
Funding: $2.1M
Jeeva's AI-driven cloud-based software provides a seamless solution that improves the experience of investigators and patients by decentralizing clinical trials.
Jeeva's AI-driven cloud-based software provides a seamless solution that improves the experience of investigators and patients by decentralizing clinical trials.
★
See also:
