Top 50 AI startups in Healthcare in USA
Mar 25, 2026
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32
1
Funding: $2.3B
Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.
Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.
2
Funding: $1.5B
Freenome has developed blood test for colorectal cancer detection based on artificial intelligence. Freenome's technology combines computational biology, machine learning and various data types to detect the most subtle signs of cancer, even in the earliest stages. In addition to colon cancer, the company is developing a test for lung cancer detection. Acquired by Perceptive Capital Solutions
Freenome has developed blood test for colorectal cancer detection based on artificial intelligence. Freenome's technology combines computational biology, machine learning and various data types to detect the most subtle signs of cancer, even in the earliest stages. In addition to colon cancer, the company is developing a test for lung cancer detection. Acquired by Perceptive Capital Solutions
3
Funding: $757.5M
Abridge is a medical conversation AI startup that offers an audio-based system to record and summarize medical conversations.
Abridge is a medical conversation AI startup that offers an audio-based system to record and summarize medical conversations.
5
Funding: $550M
Lila Sciences creates a scientific superintelligence platform and autonomous labs for life sciences, chemistry, and materials science.
Lila Sciences creates a scientific superintelligence platform and autonomous labs for life sciences, chemistry, and materials science.
6
Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
7
Funding: $457M
Metagenomi is using the power of metagenomics and machine learning to discover novel genome editing systems.
Metagenomi is using the power of metagenomics and machine learning to discover novel genome editing systems.
8
Funding: $402M
Hippocratic AI’s Aim is to develop the safest artificial Health General Intelligence (HGI).
Hippocratic AI’s Aim is to develop the safest artificial Health General Intelligence (HGI).
9
Funding: $394.3M
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
10
Funding: $387.5M
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
11
Funding: $355.2M
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
12
Funding: $328M
Clarify Health Solutions develops analytics and software solutions that enable health systems to deliver more satisfying, better outcome and higher value care
Clarify Health Solutions develops analytics and software solutions that enable health systems to deliver more satisfying, better outcome and higher value care
13
Funding: $319.3M
Ambience Healthcare is the leading AI operating system for healthcare organizations.
Ambience Healthcare is the leading AI operating system for healthcare organizations.
14
Funding: $303M
Iambic Therapeutics is built on technologies for predicting protein-ligand structures, generating molecular designs and other drug discovery tasks. Using the technologies, Iambic claims it can accelerate drug discovery, pointing to the two years it took to take its lead project from program launch to IND to make its case.
Iambic Therapeutics is built on technologies for predicting protein-ligand structures, generating molecular designs and other drug discovery tasks. Using the technologies, Iambic claims it can accelerate drug discovery, pointing to the two years it took to take its lead project from program launch to IND to make its case.
15
Funding: $300M
ConcertAI, a real-world data and artificial intelligence startup for healthcare providers and life science companies
ConcertAI, a real-world data and artificial intelligence startup for healthcare providers and life science companies
16
Funding: $300M
Concerto HealthAI is a global leader in real-world data, AI technology, and real-world evidence services for precision oncology and dedicated to engineering integrated data and technology solutions that help achieve the best possible outcomes for patients.
Concerto HealthAI is a global leader in real-world data, AI technology, and real-world evidence services for precision oncology and dedicated to engineering integrated data and technology solutions that help achieve the best possible outcomes for patients.
17
Funding: $295M
Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.
Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.
18
Funding: $291.6M
Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.
Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.
19
Funding: $256.1M
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines
20
Funding: $247M
Seismic Therapeutic is a biotechnology company advancing machine learning for immunology drug development.
Seismic Therapeutic is a biotechnology company advancing machine learning for immunology drug development.
21
Funding: $244.4M
InterVenn Biosciences is a liquid biopsy company pioneering the development of clinically useful glycoproteomic diagnostics. It has combined the molecular resolution of mass spectrometry with the power of artificial intelligence to create a unique platform for discovering new biomarkers, providing more effective treatments, developing precision medicine clinical trials, and identifying new targets. The company has also developed GlcyoKnow Ovarian, a laboratory test for assessing the risk of malignancy in confirmed pelvic lesions prior to planned surgery. It complements imaging data and clinical assessment, facilitating more informed and personalized treatment decisions.
InterVenn Biosciences is a liquid biopsy company pioneering the development of clinically useful glycoproteomic diagnostics. It has combined the molecular resolution of mass spectrometry with the power of artificial intelligence to create a unique platform for discovering new biomarkers, providing more effective treatments, developing precision medicine clinical trials, and identifying new targets. The company has also developed GlcyoKnow Ovarian, a laboratory test for assessing the risk of malignancy in confirmed pelvic lesions prior to planned surgery. It complements imaging data and clinical assessment, facilitating more informed and personalized treatment decisions.
22
Funding: $239.3M
Alto Neuroscience is a clinical-stage biopharmaceutical company that creates precision medicines through its AI-driven biomarker platform.
Alto Neuroscience is a clinical-stage biopharmaceutical company that creates precision medicines through its AI-driven biomarker platform.
23
Funding: $228.6M
CytoVale is a medical technology company that focuses on advancing early detection technologies to diagnose immune-mediated diseases.
CytoVale is a medical technology company that focuses on advancing early detection technologies to diagnose immune-mediated diseases.
24
Funding: $221.6M
Atomwise is the creator of AtomNet, the first Deep Learning technology for novel small molecule discovery, characterized by its unprecedented speed, accuracy, and diversity.
Atomwise is the creator of AtomNet, the first Deep Learning technology for novel small molecule discovery, characterized by its unprecedented speed, accuracy, and diversity.
25
Funding: $220M
Paige.AI was one of the first startups to apply AI models to cancer care and has since developed numerous models used for tissue analysis, tissue subtyping and molecular biomarker discovery. Paige has developed several AI applications for diagnostic decision support in oncology pathology, including prostate cancer detection and diagnosis in whole-section prostate biopsy images, identifying and classifying breast cancer in whole-section biopsy and excisional breast specimens, detecting and classifying benign and malignant diseases throughout the gastrointestinal tract. Developed using Virchow and trained on over 1.5 million slides, the Paige PanCancer Suite helps pathologists identify the subtlest nuances of cancer progression in various tissue types, including rare cancers. Acquired by Tempus
Paige.AI was one of the first startups to apply AI models to cancer care and has since developed numerous models used for tissue analysis, tissue subtyping and molecular biomarker discovery. Paige has developed several AI applications for diagnostic decision support in oncology pathology, including prostate cancer detection and diagnosis in whole-section prostate biopsy images, identifying and classifying breast cancer in whole-section biopsy and excisional breast specimens, detecting and classifying benign and malignant diseases throughout the gastrointestinal tract. Developed using Virchow and trained on over 1.5 million slides, the Paige PanCancer Suite helps pathologists identify the subtlest nuances of cancer progression in various tissue types, including rare cancers. Acquired by Tempus
26
Funding: $220M
Soley Therapeutics has developed a platform that uses computer vision to capture the response of living cells to drug stress, transforming image characteristics into structured data and uses AI to distinguish drug activity from toxicity, identify mechanisms of action, identify pathways for new drug discovery. Computer vision recognizes features invisible to the human eye that result from a variety of intracellular events, such as protein movement, localization, expression and organelle and membrane dynamics. The company's automated infrastructure enables the screening of over 100,000 compounds per week. The company's first drugs have demonstrated high preclinical efficacy in both hematological and solid tumors. They are also being tested for the treatment of neurodegenerative diseases, obesity/metabolic diseases and hair regeneration.
Soley Therapeutics has developed a platform that uses computer vision to capture the response of living cells to drug stress, transforming image characteristics into structured data and uses AI to distinguish drug activity from toxicity, identify mechanisms of action, identify pathways for new drug discovery. Computer vision recognizes features invisible to the human eye that result from a variety of intracellular events, such as protein movement, localization, expression and organelle and membrane dynamics. The company's automated infrastructure enables the screening of over 100,000 compounds per week. The company's first drugs have demonstrated high preclinical efficacy in both hematological and solid tumors. They are also being tested for the treatment of neurodegenerative diseases, obesity/metabolic diseases and hair regeneration.
27
Funding: $208.8M
Reveleer is a healthcare SaaS platform that uses ML and AI to empower health plans with control over their quality and risk programs.
Reveleer is a healthcare SaaS platform that uses ML and AI to empower health plans with control over their quality and risk programs.
28
Funding: $203M
Qventus is an AI-based software platform that solves operational challenges across the hospital including emergency departments, perioperative areas, and patient safety.
Qventus is an AI-based software platform that solves operational challenges across the hospital including emergency departments, perioperative areas, and patient safety.
29
Funding: $200M
Terray Therapeutics is a biotechnology company that propels drug discovery into the information age.
Terray Therapeutics is a biotechnology company that propels drug discovery into the information age.
30
Funding: $186M
BioXcel Therapeutics is a clinical stage biopharmaceutical company that utilizes novel artificial intelligence, or AI, to identify the next wave of medicines across neuroscience and immuno-oncology.
BioXcel Therapeutics is a clinical stage biopharmaceutical company that utilizes novel artificial intelligence, or AI, to identify the next wave of medicines across neuroscience and immuno-oncology.
31
Funding: $185.9M
Well Dot is an artificial intelligence startup that uses data and behavioral economics to provide daily health recommendations
Well Dot is an artificial intelligence startup that uses data and behavioral economics to provide daily health recommendations
32
Funding: $173.4M
IDx is a leading AI diagnostics company on a mission to transform the quality, accessibility, and affordability of healthcare. The company’s first product, IDx-DR, is an FDA-cleared AI-based diagnostic system designed for use at the front lines of care to detect diabetic retinopathy. IDx is developing additional AI-based diagnostic algorithms for the detection of macular degeneration, glaucoma, Alzheimer’s disease, cardiovascular disease, and stroke risk.
IDx is a leading AI diagnostics company on a mission to transform the quality, accessibility, and affordability of healthcare. The company’s first product, IDx-DR, is an FDA-cleared AI-based diagnostic system designed for use at the front lines of care to detect diabetic retinopathy. IDx is developing additional AI-based diagnostic algorithms for the detection of macular degeneration, glaucoma, Alzheimer’s disease, cardiovascular disease, and stroke risk.
33
Funding: $173.2M
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
34
Funding: $166.2M
Elucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology.
Elucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology.
36
Funding: $155M
Qualified Health develops a platform that provides health organizations with the infrastructure to deploy and scale generative AI, including governance frameworks, post-deployment monitoring and role-based access controls. The platform also includes a risk alert system, data privacy protections designed to mitigate AI hallucinations, and a healthcare-focused AI agent creation tool to automate administrative workflows.
Qualified Health develops a platform that provides health organizations with the infrastructure to deploy and scale generative AI, including governance frameworks, post-deployment monitoring and role-based access controls. The platform also includes a risk alert system, data privacy protections designed to mitigate AI hallucinations, and a healthcare-focused AI agent creation tool to automate administrative workflows.
37
Funding: $152.7M
nference Artificial Intelligence AI technology (nferX) enables Knowledge Synthesis from unstructured text & structured biomedical databases.
nference Artificial Intelligence AI technology (nferX) enables Knowledge Synthesis from unstructured text & structured biomedical databases.
38
Funding: $134.9M
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
39
Funding: $134.1M
We use genomic data to find better drugs, faster. We find new cures for brain diseases 1000X more cheaply and quickly using our proven network algorithms.
We use genomic data to find better drugs, faster. We find new cures for brain diseases 1000X more cheaply and quickly using our proven network algorithms.
40
Funding: $130.6M
Overjet combines deep learning of dental images and data science to empower dental providers and payers to deliver the best patient care.
Overjet combines deep learning of dental images and data science to empower dental providers and payers to deliver the best patient care.
41
Funding: $129.8M
Proscia makes digital pathology software and AI applications for cancer diagnosis.
Proscia makes digital pathology software and AI applications for cancer diagnosis.
42
Funding: $128M
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
43
Funding: $125.3M
Flywheel is transforming research productivity, collaboration, and reproducibility with a next generation platform for imaging and machine learning in life sciences, clinical, and academic research.
Flywheel is transforming research productivity, collaboration, and reproducibility with a next generation platform for imaging and machine learning in life sciences, clinical, and academic research.
44
Funding: $122.5M
Cellino is on a mission to make personalized, autologous stem cell therapies accessible for patients. Cellino’s platform combines label-free imaging and high-speed laser editing with machine learning to automate cell reprogramming
Cellino is on a mission to make personalized, autologous stem cell therapies accessible for patients. Cellino’s platform combines label-free imaging and high-speed laser editing with machine learning to automate cell reprogramming
45
Funding: $123.3M
Woebot Health offers digital therapeutics to make mental health radically accessible.
Woebot Health offers digital therapeutics to make mental health radically accessible.
46
Funding: $119.2M
Notable uses AI to automate and digitize every physician-patient interaction. It automtes recording of doctor’s visits and updating of electronic health records. The company has developed a technology that uses natural language processing and voice recognition to automatically record doctor-patient interactions and structure the data for inclusion in a patient’s medical records.
Notable uses AI to automate and digitize every physician-patient interaction. It automtes recording of doctor’s visits and updating of electronic health records. The company has developed a technology that uses natural language processing and voice recognition to automatically record doctor-patient interactions and structure the data for inclusion in a patient’s medical records.
47
Funding: $110M
Artera is developing an AI system for prostate cancer diagnostics. It analyzes patient biopsy images and accurately predicts the likelihood of benefit from specific treatments, allowing doctors to make treatment decisions with greater confidence. The system is based on a multimodal AI model trained on digital pathological images and text-based clinical data. In addition to images, it analyzes numerous patient characteristics and performs tasks that traditional methods cannot perform independently. Test results are generated without the use of tissue and are available for review within 2-3 days of receiving the patient's sample.
Artera is developing an AI system for prostate cancer diagnostics. It analyzes patient biopsy images and accurately predicts the likelihood of benefit from specific treatments, allowing doctors to make treatment decisions with greater confidence. The system is based on a multimodal AI model trained on digital pathological images and text-based clinical data. In addition to images, it analyzes numerous patient characteristics and performs tasks that traditional methods cannot perform independently. Test results are generated without the use of tissue and are available for review within 2-3 days of receiving the patient's sample.
48
Funding: $109M
Dyno Therapeutics is a biotechnology company that uses artificial intelligence (AI) to gene therapy.
Dyno Therapeutics is a biotechnology company that uses artificial intelligence (AI) to gene therapy.
49
Funding: $105.7M
Nayya helps businesses, carriers, brokers, and associations use data science and machine learning to help improve how people interact with their benefits. It uses AI and data science to personalize the way that employees choose and use their existing employee benefits.
Nayya helps businesses, carriers, brokers, and associations use data science and machine learning to help improve how people interact with their benefits. It uses AI and data science to personalize the way that employees choose and use their existing employee benefits.
50
Funding: $103M
Infinitus is a startup company that develops voice robotic process automation tools for the health care industry.
Infinitus is a startup company that develops voice robotic process automation tools for the health care industry.
