Top 10 Obesity treatment startups in USA

Dec 05, 2024 | By Jason Kwon

1
Funding: $3.2M
MelliCell develops therapeutics for diabetes and obesity using a proprietary in vitro model of weight gain in human fat cells.
2
Funding: $400M
Kailera Therapeutics is a clinical-stage biotechnology company developing anti-obesity drugs.
3
Funding: $1B
Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
4
Funding: $544.8M
Carmot Therapeutics provides drugs to treat inflammatory, metabolic, and neurological diseases.
5
Funding: $301M
Viome has developed technology aimed at balancing microorganisms in the gut. With Viome, you can fine-tune the function of your gut microbiome with a personalized diet to minimize the production of harmful metabolites and maximize the production of beneficial ones, so that you experience increased energy and general well-being, all while reaching and maintaining a healthy state of balance.
6
Funding: $293.9M
BioAge Labs is a clinical-stage biotechnology company that develops therapeutics to treat obesity and metabolic diseases.
7
Funding: $290M
Our purpose is to reduce the physical, emotional and economic burdens of obesity as a driver of diseases, creating value for the people we serve and the investors we work for.
8
Funding: $198.4M
Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
9
Funding: $185.6M
ReShape Lifesciences is a developer of minimally invasive medical devices to treat obesity and metabolic diseases.
10
Funding: $167M
Rivus Pharmaceuticals is dedicated to improving metabolic health by developing controlled metabolic accelerators (CMAs) that treat metabolic disorders, including the tricky nonalcoholic steatohepatitis (NASH), cardio-metabolic diseases and obesity, via weight loss.
11
Funding: $161.2M
EnteroMedics is the developer of in-class weight loss treatments for obesity and obesity related risk factors.
12
Funding: $127.6M
Calibrate is a digital metabolic health business that provides a virtual program for weight loss.
13
Funding: $81.5M
USGI Medical develops technologies to enable incisionless surgeries that treat diseases through the natural passageways of the body. The goal is to reduce the size of the stomach using proprietary tissue anchors using a noninvasive, endoscopic procedure requiring no incisions.
14
Funding: $64.3M
Form Health is a telemedical weight loss company that focuses on individuals dealing with obesity.
15
Funding: $49.2M
ValenTx has developed the ValenTx endoluminal bypass therapy that requires no surgery, stapling or permanent modification of the obese patient's anatomy.
16
Funding: $30M
Cloud Health Systems provides consultations and other health services to consumers, first focusing on metabolic health and obesity.
17
Funding: $11M
Phenomix Sciences an early-stage spinout of the Mayo Clinic focused on personalized treatments for chronic diseases. Its first product tackles obesity with a novel blood-based test that is designed to accurately predict the subtype of obesity with a sensitivity and specificity >90%.
18
Funding: $5.6M
Ilant Health provides treatment for obesity and weight management.
19
Funding: $3.3M
Adipo Therapeutics is developing polymer-based, Notch-inhibiting nanoparticles that are injected directly into adipose (fat) tissue to induce browning, or white-to-beige adipocyte transformation.
20

Kintai is a biotechnology company that advancing precision therapeutics based on enteric signaling networks in the human body.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com