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Top 28 Gastroenterology startups
Sep 29, 2025 | By Jason Kwon | 20 |
Gastroenterology startups are developing solutions such as AI-powered diagnostic algorithms, capsule endoscopy, smart pills for targeted drug delivery, virtual colonoscopy, fecal microbiota transplantation, robotic-assisted surgery, etc.
1
Country: USA | Funding: $1.2B
Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
2
Country: USA | Funding: $537.8M
Seres Therapeutics is creating a new class of medicines to treat diseases resulting from functional deficiencies in the microbiome, a condition known as dysbiosis
Seres Therapeutics is creating a new class of medicines to treat diseases resulting from functional deficiencies in the microbiome, a condition known as dysbiosis
3
Country: USA | Funding: $441.6M
Ventyx Biosciences develops a drug for inflammatory bowel disease
Ventyx Biosciences develops a drug for inflammatory bowel disease
4
Country: USA | Funding: $407.2M
Synergy is a gastrointestinal-focused biopharmaceutical company committed to science-based innovation, providing novel treatment options for patients and healthcare providers, rewarding opportunities for our employees, and creating exceptional value for our shareholders.
Synergy is a gastrointestinal-focused biopharmaceutical company committed to science-based innovation, providing novel treatment options for patients and healthcare providers, rewarding opportunities for our employees, and creating exceptional value for our shareholders.
5
Country: USA | Funding: $220.9M
Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
Allurion Technologies develops a medical device for weight loss that can be delivered and removed without surgery or endoscopy.
6
Country: USA | Funding: $119.5M
Oshi Health is a virtual-first medical practice revolutionizing the diagnosis, management and treatment of digestive health conditions.
Oshi Health is a virtual-first medical practice revolutionizing the diagnosis, management and treatment of digestive health conditions.
7
Country: USA | Funding: $105.6M
CapsoVision is a medical device company developing gastrointestinal medical devices.
CapsoVision is a medical device company developing gastrointestinal medical devices.
8
Country: USA | Funding: $58.8M
Vivante makes a digital program for digestive health and disease called GIThrive that includes, among other tools, a 24-7 support line to a gastrointestinal care team.
Vivante makes a digital program for digestive health and disease called GIThrive that includes, among other tools, a 24-7 support line to a gastrointestinal care team.
9
Country: Italy | Funding: €39M
Enthera's mission is to find new therapeutic approaches to treat diabetes and related gastrointestinal complication (enteropathy), as well as other intestinal disorders sharing the same biological pathway.
Enthera's mission is to find new therapeutic approaches to treat diabetes and related gastrointestinal complication (enteropathy), as well as other intestinal disorders sharing the same biological pathway.
10
Country: Canada | Funding: $35.2M
Medical Device startup developing a solution to detect gastrointestinal leaks after surgical procedures.
Medical Device startup developing a solution to detect gastrointestinal leaks after surgical procedures.
11
Country: USA | Funding: $19.5M
Salvo Health offers a virtual clinic geared toward people with chronic gut problems, including irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia and small intestinal bacterial overgrowth (SIBO).
Salvo Health offers a virtual clinic geared toward people with chronic gut problems, including irritable bowel syndrome (IBS), celiac disease, gastroesophageal reflux disease (GERD), dyspepsia and small intestinal bacterial overgrowth (SIBO).
12
Country: Israel | Funding: $19M
Envizion Medical develops electromagnetic feeding tube placement devices.
Envizion Medical develops electromagnetic feeding tube placement devices.
13
Country: New Zealand | Funding: $18M
Alimetry develops Gastric Alimetry system is medical device which performs Body Surface Gastric Mapping. It is intended to record, store, view and process gastric electrophysiology as an aid in the diagnosis of various gastric disorders.
Alimetry develops Gastric Alimetry system is medical device which performs Body Surface Gastric Mapping. It is intended to record, store, view and process gastric electrophysiology as an aid in the diagnosis of various gastric disorders.
14
Country: Germany | Funding: $16M
Cara Care empowers patients suffering from chronic digestive diseases to live a healthier and happier life.
Cara Care empowers patients suffering from chronic digestive diseases to live a healthier and happier life.
15
Country: Israel | Funding: $15M
Vibrant has developed the first non-drug treatment for chronic constipation via mechanical stimulation of the gut, that helps patients obtain relief and live better with their condition. The treatment empowers physicians with digital tools to provide optimized and better care.
Vibrant has developed the first non-drug treatment for chronic constipation via mechanical stimulation of the gut, that helps patients obtain relief and live better with their condition. The treatment empowers physicians with digital tools to provide optimized and better care.
16
Country: Israel | Funding: $15M
Vibrant is a developer and producer of chemical-free capsule for constipation treatment.
Vibrant is a developer and producer of chemical-free capsule for constipation treatment.
17
Country: Singapore | Funding: $10.5M
Asian Microbiome Library microbiome company and a stool bank serving as a hub for gut microbiome therapy.
Asian Microbiome Library microbiome company and a stool bank serving as a hub for gut microbiome therapy.
18
Country: Australia | Funding: $10M
Endogene has developed a self-advancing single-use gastrointestinal endoscope platform. Provides safe, timely, relaible and cost-effective access to entire GI tract. Advanced 4k imaging and AI-assisted diagnose.
Endogene has developed a self-advancing single-use gastrointestinal endoscope platform. Provides safe, timely, relaible and cost-effective access to entire GI tract. Advanced 4k imaging and AI-assisted diagnose.
19
Country: France | Funding: $10.3M
SAS TargEDys develops mechanisms involving hormone mimetic proteins linked to microbiota for the treatment of eating disorders such as hyperphagia or anorexia.
SAS TargEDys develops mechanisms involving hormone mimetic proteins linked to microbiota for the treatment of eating disorders such as hyperphagia or anorexia.
20
Country: USA | Funding: $6.4M
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
