Top 81 Digital Therapeutics startups

Updated: Apr 18, 2026
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These startups develop evidence-based therapeutic interventions driven by software to prevent, manage, or treat a medical disorders or diseases.
1
Click Therapeutics
Country: USA | Funding: $1.1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
2
Omada Health
Country: USA | Funding: $528.5M
A digital behavioral medicine company dedicated to inspiring and empowering people everywhere to live free of chronic illiness.
3
Sword Health
Country: Portugal | Funding: $493.5M
SWORD Health is a medical company that created the first AI-powered digital physical therapist, shifting healthcare from analog to digital.
4
Cerebral
Country: USA | Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
5
Maven Clinic
Country: USA | Funding: $417.1M
Maven Clinic is a virtual clinic dedicated for women and family health. It assists mothers and families during conception, throughout pregnancy, and postpartum.
6
Talkspace
Country: USA | Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
7
Virta
Country: USA | Funding: $373M
Virta is the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.
8
DarioHealth
Country: USA | Funding: $320.5M
DarioHealth is a digital therapeutics company engaged in the development and commercialization of patented and proprietary technology.
9
Akili Interactive Labs
Country: USA | Funding: $301.1M
Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games. It aims to develop a new type of electronic medicine that can be deployed remotely directly to any patient anywhere, prescribed and tracked by physicians, with the potential to be developed at a fraction of the cost of traditional medical approaches.
10
Thirty Madison
Country: USA | Funding: $229.5M
Thirty Madison develops a platform called Cove, which lets migraine patients virtually consult doctors and get medications through the mail.
11
Lark Health
Country: USA | Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
12
Lark
Country: USA | Funding: $195.7M
Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.
13
Doktor.se
Country: Sweden | Funding: $189.9M
Doktor.se is a modern and personal care company working with digital healthcare.
14
Workit Health
Country: USA | Funding: $138.2M
Workit Health is a virtual clinic dedicated to medically-assisted treatment and online therapy for substance use disorder.
15
Sanity Group
Country: Germany | Funding: $134.7M
Sanity Group is a holistic European Cannabis company focusing on health, wellbeing, and scientific research.
16
Numan
Country: UK | Funding: $130.7M
Numan is a startup which aims to tackle your tackle problem erectile dysfunction.
17
Calibrate
Country: USA | Funding: $127.6M
Calibrate is a digital metabolic health business that provides a virtual program for weight loss.
18
Sidekick Health
Country: USA | Funding: $125.7M
Sidekick Health has built a gamified digital care platform that targets chronic and lifestyle disease management via digital nudges from a helmet-wearing cartoon helper — pushing patients toward relevant information to support more beneficial lifestyle choices
19
Kaia Health
Country: Germany | Funding: $125M
kaia is a digital therapeutics company focused on AI-powered management of chronic pain
20
Holmusk
Country: Singapore | Funding: $106.2M
Holmusk is a data science and health technology company that aims to reverse chronic disease and behavioral health issues. The company develops innovative, scalable and cost-effective digital disease management programs to help patients improve their health.
21
CureApp
Country: Japan | Funding: ¥13.3B
CureApp is involved in the research and development of prescription and non-prescription digital therapeutics applications. CureApp's prescription DTx app is used for the treatment of hypertension.
22
Lumeon
Country: UK | Funding: $89.9M
Lumeon is a digital health company that provides care pathway management solutions to the healthcare industry.
23
Boulder
Country: USA | Funding: $85.2M
Boulder connects patients seeking treatment for opioid use disorder to teams of addiction specialist, care coordinators and peer coaches through a telemedicine platform.
24
NOCD
Country: USA | Funding: $84M
nOCD offers a mobile mental health app. Our goal is to revolutionize OCD treatment.
25
Felix Health
Country: Canada | Funding: $76.8M
Felix is a digital healthcare company providing seamless access to medication through online diagnoses and delivery.
26
Meru Health
Country: USA | Funding: $53.3M
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
27
Axena Health
Country: USA | Funding: $51.8M
Axena Health is company dedicated to improving the lives of women with pelvic floor disorders by leveraging the power of digital technology.
28
Legacy
Country: USA | Funding: $47.2M
Legacy is a digital fertility clinic for men
29
Temedica
Country: Germany | Funding: $44.8M
Temedica is a digital health company with the mission to put the patient into the center of healthcare. To this end, the company offers solutions both for patients and for other stakeholders in the healthcare universe.
30
Liva Healthcare
Country: Denmark | Funding: $43.5M
Liva’s digital coaching platform provides scalable lifestyle change, disease management & patient engagement for NHS England, AXA PPP & more
31
Healthie
Country: USA | Funding: $40.9M
Healthie offers infrastructure for next gen digital health companies that offer virtual-first care. API-First EHR & Client Engagement.
32
Alpha Medical
Country: USA | Funding: $35M
Alpha Medical is a virtual primary care company focused on women’s health
33
Mantra Health
Country: USA | Funding: $34.2M
Mantra Health is a digital mental healthcare company designed for all university students.
34
Swing Therapeutics
Country: USA | Funding: $34M
Swing Therapeutics provides digital therapeutics for people with chronic conditions.
35
Joint Academy
Country: Sweden | Funding: $33.2M
Joint Academy is a digital clinic that provides digital treatment for patients with osteoarthritis and chronic joint pain.
36
HelloSelf
Country: UK | Funding: $31.3M
HelloSelf is a health and wellness platform that provides its users with digital access to therapists.
37
Reperio Health
Country: USA | Funding: $26.7M
Reperio is the only at-home health assessment that provides comprehensive results immediately.
38
SilverCloud Health
Country: USA | Funding: $26.2M
SilverCloud Health develops leading digital mental and behavioral health platform
39
Tripp
Country: USA | Funding: $26.3M
The award-winning digital psychedelic wellness platform that uses the power of virtual and augmented reality to change the way you feel.
40
Monument
Country: USA | Funding: $23.6M
Monument is an alcohol addiction treatment platform for those looking to change their relationship with alcohol.
41
ANDHealth
Country: Australia | Funding: $21.4M
ANDHealth is an integrated ecosystem for the development & commercialisation of evidence-based digital health products.
42
RxLightning
Country: USA | Funding: $20.5M
RxLightning automates the manual enrollment process of starting a patient on specialty medications.
43
Culina Health
Country: USA | Funding: $20.8M
Culina Health making nutrition accessible & sustainable for everyone.
44
Omcare
Country: USA | Funding: $20.2M
Ōmcare is a digital health company focused on enabling care in the home so that seniors can age in place while maintaining optimal health and well-being. Ōmcare Home Health Hub enables remote care and visual confirmation
45
Mindset Health
Country: Australia | Funding: $19.7M
Mindset Health helps improve recurring health issues like irritable bowel syndrome and anxiety with app-based hypnotherapy.
46
Eka Care
Country: India | Funding: $19.5M
Eka.Care is a digitally enabled and connected healthcare ecosystem focused on better health outcomes.
47
Praia Health
Country: USA | Funding: $20M
Praia Health is a modern consumer platform for health systems that transforms the delivery of tailored health solutions on a large scale.
48
JOGO Health
Country: USA | Funding: $17.6M
JOGO uses wearables and an App that leverages AI and VR to treat neuromuscular conditions and chronic pain by providing treatment protocols and games that can be adapted for muscle relaxation, movement coordination, and neuro-muscular re-education all leveraging the clinically proven science of neuroplasticity and biofeedback.
49
Fitterfly
Country: India | Funding: $18.1M
Fitterfly offers customized and personalized wellness programs for diabetes PCOS, pregnancy, weight loss, pediatric and nutrition.
50
GripAble
Country: UK | Funding: $16.3M
Gripable develops digital therapy tools, combining them with mobile games, and motivating physically impaired patients.
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com