Top 43 Digital Therapeutics startups in USA
Apr 18, 2026
|
Like
24
1
Funding: $1.1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
2
Funding: $528.5M
A digital behavioral medicine company dedicated to inspiring and empowering people everywhere to live free of chronic illiness.
A digital behavioral medicine company dedicated to inspiring and empowering people everywhere to live free of chronic illiness.
3
Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
4
Funding: $417.1M
Maven Clinic is a virtual clinic dedicated for women and family health. It assists mothers and families during conception, throughout pregnancy, and postpartum.
Maven Clinic is a virtual clinic dedicated for women and family health. It assists mothers and families during conception, throughout pregnancy, and postpartum.
5
Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
6
Funding: $373M
Virta is the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.
Virta is the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.
7
Funding: $320.5M
DarioHealth is a digital therapeutics company engaged in the development and commercialization of patented and proprietary technology.
DarioHealth is a digital therapeutics company engaged in the development and commercialization of patented and proprietary technology.
8
Funding: $301.1M
Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games. It aims to develop a new type of electronic medicine that can be deployed remotely directly to any patient anywhere, prescribed and tracked by physicians, with the potential to be developed at a fraction of the cost of traditional medical approaches.
Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games. It aims to develop a new type of electronic medicine that can be deployed remotely directly to any patient anywhere, prescribed and tracked by physicians, with the potential to be developed at a fraction of the cost of traditional medical approaches.
9
Funding: $229.5M
Thirty Madison develops a platform called Cove, which lets migraine patients virtually consult doctors and get medications through the mail.
Thirty Madison develops a platform called Cove, which lets migraine patients virtually consult doctors and get medications through the mail.
10
Funding: $195.7M
Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.
Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.
11
Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
12
Funding: $138.2M
Workit Health is a virtual clinic dedicated to medically-assisted treatment and online therapy for substance use disorder.
Workit Health is a virtual clinic dedicated to medically-assisted treatment and online therapy for substance use disorder.
13
Funding: $127.6M
Calibrate is a digital metabolic health business that provides a virtual program for weight loss.
Calibrate is a digital metabolic health business that provides a virtual program for weight loss.
14
Funding: $125.7M
Sidekick Health has built a gamified digital care platform that targets chronic and lifestyle disease management via digital nudges from a helmet-wearing cartoon helper — pushing patients toward relevant information to support more beneficial lifestyle choices
Sidekick Health has built a gamified digital care platform that targets chronic and lifestyle disease management via digital nudges from a helmet-wearing cartoon helper — pushing patients toward relevant information to support more beneficial lifestyle choices
15
Funding: $85.2M
Boulder connects patients seeking treatment for opioid use disorder to teams of addiction specialist, care coordinators and peer coaches through a telemedicine platform.
Boulder connects patients seeking treatment for opioid use disorder to teams of addiction specialist, care coordinators and peer coaches through a telemedicine platform.
16
Funding: $84M
nOCD offers a mobile mental health app. Our goal is to revolutionize OCD treatment.
nOCD offers a mobile mental health app. Our goal is to revolutionize OCD treatment.
17
Funding: $53.3M
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
18
Funding: $51.8M
Axena Health is company dedicated to improving the lives of women with pelvic floor disorders by leveraging the power of digital technology.
Axena Health is company dedicated to improving the lives of women with pelvic floor disorders by leveraging the power of digital technology.
20
Funding: $40.9M
Healthie offers infrastructure for next gen digital health companies that offer virtual-first care. API-First EHR & Client Engagement.
Healthie offers infrastructure for next gen digital health companies that offer virtual-first care. API-First EHR & Client Engagement.
21
Funding: $35M
Alpha Medical is a virtual primary care company focused on women’s health
Alpha Medical is a virtual primary care company focused on women’s health
22
Funding: $34.2M
Mantra Health is a digital mental healthcare company designed for all university students.
Mantra Health is a digital mental healthcare company designed for all university students.
23
Funding: $34M
Swing Therapeutics provides digital therapeutics for people with chronic conditions.
Swing Therapeutics provides digital therapeutics for people with chronic conditions.
24
Funding: $26.7M
Reperio is the only at-home health assessment that provides comprehensive results immediately.
Reperio is the only at-home health assessment that provides comprehensive results immediately.
25
Funding: $26.3M
The award-winning digital psychedelic wellness platform that uses the power of virtual and augmented reality to change the way you feel.
The award-winning digital psychedelic wellness platform that uses the power of virtual and augmented reality to change the way you feel.
26
Funding: $26.2M
SilverCloud Health develops leading digital mental and behavioral health platform
SilverCloud Health develops leading digital mental and behavioral health platform
27
Funding: $23.6M
Monument is an alcohol addiction treatment platform for those looking to change their relationship with alcohol.
Monument is an alcohol addiction treatment platform for those looking to change their relationship with alcohol.
28
Funding: $20.5M
RxLightning automates the manual enrollment process of starting a patient on specialty medications.
RxLightning automates the manual enrollment process of starting a patient on specialty medications.
30
Funding: $20M
Praia Health is a modern consumer platform for health systems that transforms the delivery of tailored health solutions on a large scale.
Praia Health is a modern consumer platform for health systems that transforms the delivery of tailored health solutions on a large scale.
31
Funding: $20.2M
Ōmcare is a digital health company focused on enabling care in the home so that seniors can age in place while maintaining optimal health and well-being. Ōmcare Home Health Hub enables remote care and visual confirmation
Ōmcare is a digital health company focused on enabling care in the home so that seniors can age in place while maintaining optimal health and well-being. Ōmcare Home Health Hub enables remote care and visual confirmation
32
Funding: $17.6M
JOGO uses wearables and an App that leverages AI and VR to treat neuromuscular conditions and chronic pain by providing treatment protocols and games that can be adapted for muscle relaxation, movement coordination, and neuro-muscular re-education all leveraging the clinically proven science of neuroplasticity and biofeedback.
JOGO uses wearables and an App that leverages AI and VR to treat neuromuscular conditions and chronic pain by providing treatment protocols and games that can be adapted for muscle relaxation, movement coordination, and neuro-muscular re-education all leveraging the clinically proven science of neuroplasticity and biofeedback.
33
Funding: $16M
Limber is a digital home-exercise, remote monitoring, data analytics, and care navigation solution for musculoskeletal (MSK) conditions.
Limber is a digital home-exercise, remote monitoring, data analytics, and care navigation solution for musculoskeletal (MSK) conditions.
37
Funding: $6.7M
Veris Health is a digital health company that provides cancer care platform.
Veris Health is a digital health company that provides cancer care platform.
38
Funding: $6.4M
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
MetaMe Health is committed to developing FDA-approved prescription digital therapeutics for the treatment of gastrointestinal conditions.
39
Funding: $4.8M
Our digital health platform helps researchers and clinicians create validated real-world programs with less hassle and more impact.
Our digital health platform helps researchers and clinicians create validated real-world programs with less hassle and more impact.
40
Funding: $4.5M
genneve, a digital health company for women in midlife & menopause. genneve increases accessibility to information, health providers and community for women seeking relief for hormone-driven symptoms like hot flashes, insomnia, anxiety and loss of libido.
genneve, a digital health company for women in midlife & menopause. genneve increases accessibility to information, health providers and community for women seeking relief for hormone-driven symptoms like hot flashes, insomnia, anxiety and loss of libido.
41
Funding: $1.5M
Wise develops gamified OTC and prescription digital therapeutics that are help people achieve mental well-being
Wise develops gamified OTC and prescription digital therapeutics that are help people achieve mental well-being
42
Funding: $1.1M
NightWare is an application on an Apple Watch that helps people suffering from traumatic nightmares to get a more restful night's sleep. It is a wearable technology that learns your sleep patterns and customizes a treatment for each individual, interrupting nightmares so you can get an uninterrupted night's sleep.
NightWare is an application on an Apple Watch that helps people suffering from traumatic nightmares to get a more restful night's sleep. It is a wearable technology that learns your sleep patterns and customizes a treatment for each individual, interrupting nightmares so you can get an uninterrupted night's sleep.
43
ReachLink is a behavioral health platform offering innovative and comprehensive mental health care designed to address individual needs, ensure access to the right support and track out comes accurately. This is made possible by ReachLink's digital platform and quality care that's as effective as face-to-face therapy.
★
See also:
