Top 88 Digital Therapeutics startups

Oct 09, 2025 | By Jason Kwon

These startups develop evidence-based therapeutic interventions driven by software to prevent, manage, or treat a medical disorders or diseases.
1
Country: USA | Funding: $12M
We build technology to make health more human.
2
Country: UK | Funding: $130.7M
Numan is a startup which aims to tackle your tackle problem erectile dysfunction.
3
Country: USA | Funding: $26.7M
Reperio is the only at-home health assessment that provides comprehensive results immediately.
4
Country: Italy | Funding: $6.9M
Clinically validated and beautifully designed digital medicine and digital therapeutic solutions (DTx)
5
Country: USA | Funding: $1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
6
Country: USA | Funding: $528.5M
A digital behavioral medicine company dedicated to inspiring and empowering people everywhere to live free of chronic illiness.
7
Country: Portugal | Funding: $493.5M
SWORD Health is a medical company that created the first AI-powered digital physical therapist, shifting healthcare from analog to digital.
8
Country: USA | Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
9
Country: USA | Funding: $417.1M
Maven Clinic is a virtual clinic dedicated for women and family health. It assists mothers and families during conception, throughout pregnancy, and postpartum.
10
Country: USA | Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
11
Country: USA | Funding: $373M
Virta is the first clinically-proven treatment to safely and sustainably reverse type 2 diabetes without medications or surgery.
12
Country: USA | Funding: $303.8
DarioHealth is a digital therapeutics company engaged in the development and commercialization of patented and proprietary technology.
13
Country: USA | Funding: $301.1M
Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games. It aims to develop a new type of electronic medicine that can be deployed remotely directly to any patient anywhere, prescribed and tracked by physicians, with the potential to be developed at a fraction of the cost of traditional medical approaches.
14
Country: USA | Funding: $229.5M
Thirty Madison develops a platform called Cove, which lets migraine patients virtually consult doctors and get medications through the mail.
15
Country: USA | Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
16
Country: USA | Funding: $195.7M
Lark is a digital health startup that provides virtual care through AI coaching, smart devices, and tele-monitoring.
17
Country: Sweden | Funding: $189.9M
Doktor.se is a modern and personal care company working with digital healthcare.
18
Country: USA | Funding: $138.2M
Workit Health is a virtual clinic dedicated to medically-assisted treatment and online therapy for substance use disorder.
19
Country: Germany | Funding: $134.7M
Sanity Group is a holistic European Cannabis company focusing on health, wellbeing, and scientific research.
20
Country: USA | Funding: $127.6M
Calibrate is a digital metabolic health business that provides a virtual program for weight loss.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com