Top 30 Clinical Decision Support startups

Oct 02, 2025 | By Jason Kwon

These startups develop AI-based decision support systems that automatically define diagnosis and treatment plans basing on row patient data.
1
Country: USA | Funding: $106.3M
Ambience Healthcare is the leading AI operating system for healthcare organizations.
2
Country: Denmark | Funding: $93.3M
Corti is a machine learning company that helps emergency departments to detect critical illnesses like cardiac arrest in real-time.
3
Country: USA | Funding: $81.4M
Regard uses AI to automatically diagnose patients and generate accurate notes for doctors to improve patient care and reduce burnout.
4
Country: USA | Funding: $66.5M
Prognos is a healthcare AI company focused on eradicating disease by driving decisions earlier in healthcare in collaboration with payers, Life Sciences and diagnostics companies. The Prognos Registry is the largest source of clinical diagnostics information in over 30 disease areas, with over 5B medical records for 100M patients. Prognos has 500 extensive proprietary and learning clinical algorithms to enable earlier patient identification for enhanced treatment decision-making, risk management and quality improvement.
5
Country: USA | Funding: $56.8M
Summus Global is a virtual specialist platform that brings personalized advice to every medical decision.
6
Country: USA | Funding: $44M
Canvas is the first and only human-centered EMR, built to enable better clinical decisions, superior patient care, and achievable work-life balance.
7
Country: USA | Funding: $42.9 m
Improving healthcare outcomes requires access to the right data at the right time. Apixio is advancing value-based care with data-driven intelligence and analytics. Our AI-powered insights unlock actionable information from administrative and unstructured clinical data. The results drive better decision-making and a smarter approach to healthcare.
8
Country: China | Funding: $30M
Huimei Technology develops and designs medical artificial intelligence solutions that focus on improving clinical quality. Products include clinical decision support system, disease process quality management system, medical knowledge base, using natural language processing, deep learning and other AI techniques to process clinical big data.
9
Country: USA | Funding: $26.6M
Story Health helps specialists to understand medical situations and make clinical decisions that are through virtual protocols.
10
Country: Israel | Funding: $26M
MDI Health offers an AI-powered platform that provides unique decision support tools for personalized drug treatments.
11
Country: USA | Funding: $25M
Layer Health is a platform that enables the healthcare industry to correctly, scalably, and reliably extract the insights from health data.
12
Country: UK | Funding: $15.9M
RwHealth’s platform combines AI machine learning and data science to give healthcare providers access to data which can aid their decision-making.
13
Country: USA | Funding: $12.7M
Ambient Clinical Analytics sells clinical decision support systems to hospitals to reduce overall health care costs and improve patient outcomes.
14
Country: USA | Funding: $12.8M
InsightRX is a software platform that incorporates the principles of quantitative pharmacology and machine learning to provide an individualized understanding of a patient’s response to treatment. It delivers its technology in the form of easy-to-use clinical decision support tools at the point-of-care to help guide treatment decision-making. The platform guides treatment decisions at both the individual level and the population level.
15
Country: Israel | Funding: $10.6M
Kahun develops AI enabled clinical reasoning chatbot
16
Country: USA | Funding: $10M
Mednition offers a machine learning-powered decision support solution for hospitals. It provides real-time analytics solutions to the Health Care community and brings together health care information and machine learning to improve patient outcomes, lower risk, and reduce costs for health care providers.
17
Country: USA | Funding: $9M
MaxQ-AI delivers artificial intelligence based decision support to improve clinical outcomes.
18
Country: USA | Funding: $8.5M
SaVia Health develops software that provides real decision support to clinicians at the point of care.
19
Country: USA | Funding: $8M
AvoMD is reimagining decision support with no code software and point-of-care innovation.
20
Country: USA | Funding: $7M
Glass Health empowers clinicians with a platform for AI-assisted diagnosis and clinical decision-making
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com