Top 23 Clinical Decision Support startups

Updated: Dec 26, 2025
|
These startups develop AI-based decision support systems that automatically define diagnosis and treatment plans basing on row patient data.
1
Ambience Healthcare
Country: USA | Funding: $319.3M
Ambience Healthcare is the leading AI operating system for healthcare organizations.
2
Artera
Country: USA | Funding: $110M
Artera is developing an AI system for prostate cancer diagnostics. It analyzes patient biopsy images and accurately predicts the likelihood of benefit from specific treatments, allowing doctors to make treatment decisions with greater confidence. The system is based on a multimodal AI model trained on digital pathological images and text-based clinical data. In addition to images, it analyzes numerous patient characteristics and performs tasks that traditional methods cannot perform independently. Test results are generated without the use of tissue and are available for review within 2-3 days of receiving the patient's sample.
3
Corti
Country: Denmark | Funding: $93.3M
Corti is a machine learning company that helps emergency departments to detect critical illnesses like cardiac arrest in real-time.
4
Regard
Country: USA | Funding: $81.4M
Regard uses AI to automatically diagnose patients and generate accurate notes for doctors to improve patient care and reduce burnout.
5
Prognos
Country: USA | Funding: $66.5M
Prognos is a healthcare AI company focused on eradicating disease by driving decisions earlier in healthcare in collaboration with payers, Life Sciences and diagnostics companies. The Prognos Registry is the largest source of clinical diagnostics information in over 30 disease areas, with over 5B medical records for 100M patients. Prognos has 500 extensive proprietary and learning clinical algorithms to enable earlier patient identification for enhanced treatment decision-making, risk management and quality improvement.
6
Summus Global
Country: USA | Funding: $64.3M
Summus Global is a virtual specialist platform that brings personalized advice to every medical decision.
7
Canvas Medical
Country: USA | Funding: $44M
Canvas is the first and only human-centered EMR, built to enable better clinical decisions, superior patient care, and achievable work-life balance.
8
Huimei Healthcare
Country: China | Funding: $30M
Huimei Technology develops and designs medical artificial intelligence solutions that focus on improving clinical quality. Products include clinical decision support system, disease process quality management system, medical knowledge base, using natural language processing, deep learning and other AI techniques to process clinical big data.
9
Story Health
Country: USA | Funding: $26.6M
Story Health helps specialists to understand medical situations and make clinical decisions that are through virtual protocols.
10
MDI Health
Country: Israel | Funding: $26M
MDI Health offers an AI-powered platform that provides unique decision support tools for personalized drug treatments.
11
Layer Health
Country: USA | Funding: $25M
Layer Health is a platform that enables the healthcare industry to correctly, scalably, and reliably extract the insights from health data.
12
Ambient Clinical Analytics
Country: USA | Funding: $12.7M
Ambient Clinical Analytics sells clinical decision support systems to hospitals to reduce overall health care costs and improve patient outcomes.
13
InsightRX
Country: USA | Funding: $12.8M
InsightRX is a software platform that incorporates the principles of quantitative pharmacology and machine learning to provide an individualized understanding of a patient’s response to treatment. It delivers its technology in the form of easy-to-use clinical decision support tools at the point-of-care to help guide treatment decision-making. The platform guides treatment decisions at both the individual level and the population level.
14
Kahun
Country: Israel | Funding: $10.6M
Kahun develops AI enabled clinical reasoning chatbot
15
Mednition
Country: USA | Funding: $10M
Mednition offers a machine learning-powered decision support solution for hospitals. It provides real-time analytics solutions to the Health Care community and brings together health care information and machine learning to improve patient outcomes, lower risk, and reduce costs for health care providers.
16
SaVia Health
Country: USA | Funding: $8.5M
SaVia Health develops software that provides real decision support to clinicians at the point of care.
17
AvoMD
Country: USA | Funding: $8M
AvoMD is reimagining decision support with no code software and point-of-care innovation.
18
Glass Health
Country: USA | Funding: $7M
Glass Health empowers clinicians with a platform for AI-assisted diagnosis and clinical decision-making
19
Keebler Health
Country: USA | Funding: $6M
Keebler Health is a developer of an AI-based risk adjustment tool for healthcare providers.
20
FeelBetter
Country: Israel | Funding: $5.9M
FeelBetter is a machine learning-enabled medication-management platform focused on polypharmacy. FeelBetter brings together data covering pharmacology, patients’ health status and medical history, clinical guidelines, and evidence-based medicine, and then leverages AI to understand the complex connections and relationships between these disparate data sources.
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com