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Top 20 Anti-Aging startups in USA
Sep 29, 2025 | By Jason Kwon | 24 |
1
Funding: $3B
Altos Labs is working on biological reprogramming technology to essentially prolong human life
Altos Labs is working on biological reprogramming technology to essentially prolong human life
2
Funding: $1.5B
Calico is Google's research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. We will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.
Calico is Google's research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. We will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.
3
Funding: $1.1B
Retro Biosciences focus on cellular reprogramming, autophagy and plasma-inspired therapeutics.
Retro Biosciences focus on cellular reprogramming, autophagy and plasma-inspired therapeutics.
4
Funding: $799M
Samumed is a leader in medical research and development for tissue-level regeneration. With our platform's origins in small molecule-based Wnt pathway modulation, we develop therapeutics to address a range of degenerative diseases, regenerative medicine and oncology.
Samumed is a leader in medical research and development for tissue-level regeneration. With our platform's origins in small molecule-based Wnt pathway modulation, we develop therapeutics to address a range of degenerative diseases, regenerative medicine and oncology.
5
Funding: $400M
Celgene spinout that aims is to develop cells from placentas against blood cancers and is founded on the use of stem cells from placentas. The goal is to create therapies across autoimmune and degenerative disease, immuno-oncology, and functional regeneration.
Celgene spinout that aims is to develop cells from placentas against blood cancers and is founded on the use of stem cells from placentas. The goal is to create therapies across autoimmune and degenerative disease, immuno-oncology, and functional regeneration.
6
Funding: $369.8M
Human Longevity is the genomics-based, technology-driven company creating the world’s largest and most comprehensive database of whole genome, phenotype and clinical data. HLI is developing and applying large scale computing and machine learning to make novel discoveries to revolutionize the practice of medicine.
Human Longevity is the genomics-based, technology-driven company creating the world’s largest and most comprehensive database of whole genome, phenotype and clinical data. HLI is developing and applying large scale computing and machine learning to make novel discoveries to revolutionize the practice of medicine.
7
Funding: $366.2M
Alzheon is committed to developing innovative medicines for patients suffering from Alzheimer's disease and other neurological and psychiatric disorders. Our Alzheon’s drug development platform which comprises proprietary chemistries, robust clinical efficacy and safety datasets in patients and genetically-defined subpopulations, and the ability to optimize molecules to have the desired therapeutic attributes.
Alzheon is committed to developing innovative medicines for patients suffering from Alzheimer's disease and other neurological and psychiatric disorders. Our Alzheon’s drug development platform which comprises proprietary chemistries, robust clinical efficacy and safety datasets in patients and genetically-defined subpopulations, and the ability to optimize molecules to have the desired therapeutic attributes.
8
Funding: $293.9M
BioAge Labs is a clinical-stage biotechnology company that develops therapeutics to treat obesity and metabolic diseases.
BioAge Labs is a clinical-stage biotechnology company that develops therapeutics to treat obesity and metabolic diseases.
9
Funding: $294.9M
At UNITY, we design therapeutics that prevent, halt, or reverse diseases of aging. Our medicines are designed to lengthen healthspan, the amount of time you live in good health.
At UNITY, we design therapeutics that prevent, halt, or reverse diseases of aging. Our medicines are designed to lengthen healthspan, the amount of time you live in good health.
10
Funding: $206.8M
Life Biosciences engages in advancing longevity research and entrepreneurial solutions to improve and extend healthy lives. We bring together scientists and investors to find innovative solutions and move them from the lab to the market to benefit all people.
Life Biosciences engages in advancing longevity research and entrepreneurial solutions to improve and extend healthy lives. We bring together scientists and investors to find innovative solutions and move them from the lab to the market to benefit all people.
12
Funding: $115M
resTORbio is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for the treatment of aging-related diseases. esTORbio’s lead program has demonstrated in several clinical trials, including a randomized, placebo-controlled trial, the potential to treat multiple diseases of aging for which there are no approved therapies.
resTORbio is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for the treatment of aging-related diseases. esTORbio’s lead program has demonstrated in several clinical trials, including a randomized, placebo-controlled trial, the potential to treat multiple diseases of aging for which there are no approved therapies.
13
Funding: $95M
Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions in the inflammatory, cardiovascular, orthopedic and wound healing markets. The company operates its business through two segments: Therapeutics and Biosurgery segment. The Therapeutics segment focuses on developing biologic stem cell drug candidates from readily available and non-controversial sources. One of its products, Stromagen was used to treat breast cancer in clinical trials.
Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions in the inflammatory, cardiovascular, orthopedic and wound healing markets. The company operates its business through two segments: Therapeutics and Biosurgery segment. The Therapeutics segment focuses on developing biologic stem cell drug candidates from readily available and non-controversial sources. One of its products, Stromagen was used to treat breast cancer in clinical trials.
14
Funding: $71.2M
Your health starts with your cells. Deliver wellness to every cell with the world’s first cellular health supplement.
Your health starts with your cells. Deliver wellness to every cell with the world’s first cellular health supplement.
15
Funding: $64.3M
Elevian develops medicines that restore youthful regenerative capacity with the potential to treat and prevent many age-related diseases.
Elevian develops medicines that restore youthful regenerative capacity with the potential to treat and prevent many age-related diseases.
16
Funding: $56M
Function is a whole-body health company that users undergo 100+ lab tests and, based on the results, obtain a detailed clinician summary of their overall health. The tests include biomarkers that help monitor for early indicators of diseases.
Function is a whole-body health company that users undergo 100+ lab tests and, based on the results, obtain a detailed clinician summary of their overall health. The tests include biomarkers that help monitor for early indicators of diseases.
17
Funding: $50M
Alkahest is developing therapies derived from blood and its components with a focus to improve vitality and function into old age. We are working on treatments for diseases of aging, with an emphasis on cognitive dysfunction and dementia, which are key medical challenges of our generation.
Alkahest is developing therapies derived from blood and its components with a focus to improve vitality and function into old age. We are working on treatments for diseases of aging, with an emphasis on cognitive dysfunction and dementia, which are key medical challenges of our generation.
18
Funding: $36M
Neuraly is a Johns Hopkins School of Medicine spinoff biotech company and aims to introduce the first, disease-modifying agent for neurodegenerative disorders and aging.
Neuraly is a Johns Hopkins School of Medicine spinoff biotech company and aims to introduce the first, disease-modifying agent for neurodegenerative disorders and aging.
19
Funding: $32.1M
Oisín Biotechnologies' ground-breaking research and technology is demonstrating that the solution to mitigating the effects of age-related diseases is to address the damage created by the aging process itself.
Oisín Biotechnologies' ground-breaking research and technology is demonstrating that the solution to mitigating the effects of age-related diseases is to address the damage created by the aging process itself.
20
Funding: $27M
Empowering exercise programs designed just for you, so you can chase the life you want at any age.
Empowering exercise programs designed just for you, so you can chase the life you want at any age.
