Calyxo
Updated: April 14, 2026
CEO - Joe Catanese III
Country: USA | Funding: $125.4M (+)
Founded: 2016
Website: https://calyxoinc.com/
Calyxo has developed the CVAC surgical system for kidney stone removal and the corresponding procedure called SURE. The company's device utilizes irrigation and vacuum aspiration during and after laser lithotripsy to extract stones from patients' kidneys, allowing physicians to completely remove stone fragments. Independent irrigation and aspiration channels ensure continuous flow. Four angled nozzles liquefy fragments for effective removal. Dynamic aspiration removes dust during lithotripsy and removes fragments after lithotripsy. The CVAC system demonstrated safety and superior stone removal in the landmark ASPIRE study.
Founded: 2016
Website: https://calyxoinc.com/
Calyxo has developed the CVAC surgical system for kidney stone removal and the corresponding procedure called SURE. The company's device utilizes irrigation and vacuum aspiration during and after laser lithotripsy to extract stones from patients' kidneys, allowing physicians to completely remove stone fragments. Independent irrigation and aspiration channels ensure continuous flow. Four angled nozzles liquefy fragments for effective removal. Dynamic aspiration removes dust during lithotripsy and removes fragments after lithotripsy. The CVAC system demonstrated safety and superior stone removal in the landmark ASPIRE study.
