Top 100 medical and healthcare startups in USA

Apr 15, 2025 | By Jason Kwon

1
Funding: $245M
AIRNA develops RNA editing technologies to create medicines for various diseases.
2
Funding: $30.8M
Pelage Pharma delivers a clinically tested treatment for both men and women battling the emotional pain or social stigma of hair loss.
3
Funding: $662.7M
Aura provides AI-powered security solutions that offer identity theft protection, credit monitoring, and online privacy for individuals.
4
Funding: $426.1M
Neurona Therapeutics develops cell therapies for neurological disorders, focusing on treatments like NRTX-1001 for epilepsy.
5
Funding: $237.6M
Atsena Therapeutics develops blindness gene therapy
6
Funding: $196M
Curevo is a clinical-stage biotechnology company developing next-generation, non-mRNA vaccines for infectious diseases.
7
Funding: $120M
Character Bio is a platform that merges genomics with clinical data and AI technology, focusing on patients affected by AMD.
8
Funding: $82.8M
Sibel Health develops a neonatal epidermal system designed for wireless vital signs monitoring.
9
Funding: $6M
Affineon Labs Core automates inbox items the provider doesn’t want to see and reduces time needed for the ones they do want to see.
10
Funding: $304.5M
Arbor Biotechnologies is an operator of a bio-discovery company intended to provide human diagnostic development services.
11
Funding: $298.2M
ShiftMed offers a nursing jobs app for the healthcare industry.
12
Funding: $276.8M
Aviceda Therapeutics is a late-stage, pre-clinical biotech company developing drugs for treating glyco-immune diseases.
13
Funding: $253.8M
Elicio Therapeutics is a pharmaceutical research company that develops an immuno-tumor vaccine to treat cancer.
14
Funding: $223.9M
Senti is using the latest techniques in the fields to build the future of gene and cell-based therapies. Senti’s proprietary synthetic biology platform provides fundamental advantages for therapeutics development.
15
Funding: $187M
Callio Therapeutics develops next-generation, multi-payload antibody-drug conjugates (ADCs).
16
Funding: $134.2M
SiteOne Therapeutics is a biopharmaceutical company that develops pain therapeutics to treat sensory hyperexcitability disorders.
17
Funding: $99.6M
Incredible Health is a medical and health platform that connects health systems with nurses.
18
Funding: $99.8M
Candid Health provides an automation platform for healthcare revenue cycle management.
19
Funding: $92.1M
Elucent Medical provides surgical navigation solutions to enhance patient care.
20
Funding: $84M
Health benefits startup Thatch offers benefits to supplement health plans, like a Health Savings Account, a debit card for healthcare expenses and access to experts who can help resolve billing issues.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com