Top 11 Radiopharmaceutical startups

Updated: Dec 25, 2025
|
These startups develop drugs that contains a radioactive substance used to destroy cancer cells or other pathogenic tissues.
1
RayzeBio
Country: USA | Funding: $418M
RayzeBio is focused on improving outcomes for people with cancer by harnessing the power of targeted radioisotopes.
2
Aktis Oncology
Country: USA | Funding: $331M
Aktis Oncology develops radiopharmaceutical treatments for solid tumors.
3
Alpha-9 Oncology
Country: Canada | Funding: $259M
Alpha9 Theranostics is a biopharma company that focuses on radiotherapeutics for the treatment of solid and hematologic malignancies.
4
Mariana Oncology
Country: USA | Funding: $250M
Mariana Oncology designs radiopharmaceuticals to pierce solid tumors better than antibodies and deliver optimized high radiation activity doses without the side effects tied to chemotherapy and toxin-based strategies.
5
Artbio
Country: USA | Funding: $245M
ARTBIO is a clinical-stage radiopharmaceutical biotechnology business that is working to create a new class of alpha radioligand medicines.
6
Abdera Therapeutics
Country: Canada | Funding: $148.3M
Abdera is an oncology company developing targeted alpha therapies (TATs) for patients with relapsed, refractory, and metastatic cancers.
7
AdvanCell
Country: Australia | Funding: $137.9M
AdvanCell is a clinical-stage radiopharmaceutical company that develops novel cancer therapeutics.
8
Radionetics Oncology
Country: USA | Funding: $135M
Radionetics Oncology is a pharmaceutical company that focuses on the discovery and development of novel radiotherapeutics.
9
Convergent Therapeutics
Country: USA | Funding: $130M
Convergent Therapeutics develops radiopharmaceuticals for the treatment of prostate cancer. These are radioantibodies that deliver alpha-emitting agents, which carry the radioactive payload directly to the cancer cells, making radiation therapy more targeted and effective. The short-acting nature of these alpha-emitting agents minimizes radiation exposure to healthy adjacent cells and tissue. Each radioantibody is created through careful selection of an antibody with high affinity for a specific cancer target. The company's flagship drug, CONV01-α, is a radioantibody labeled with actinium-225, with proven efficacy and safety in multiple Phase 1/2 trials in prostate cancer patients.
10
MedTrace
Country: Denmark | Funding: $52.3M
MedTrace provides 15O water for positron emission tomography (PET) imaging. The startup’s platform consists of an automated hardware system for producing, dosing, and injecting 15O water and analytical software for image processing.
11
Navigo Proteins
Country: Germany
Navigo Proteins develops novel radio-conjugates. The startup engineers Affilin, artificial proteins designed to selectively bind antigens, radio conjugates.
  See also:
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com