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Top 14 Orthopedics startups
Sep 22, 2025 | By Jason Kwon | 22 |
These startups create new technologies like 3d printing for custom implants, robotic-assisted surgery, artificial intelligence in imaging, stem cell therapy, computer-assisted orthopedic surgery (CAOS), minimally invasive endoscopic techniques.
1
Country: USA | Funding: $109.3M
Vori Health offers a nationwide, all-inclusive medical practice that is uniquely positioned to address back, neck, and other joint issues.
Vori Health offers a nationwide, all-inclusive medical practice that is uniquely positioned to address back, neck, and other joint issues.
2
Country: USA | Funding: $95M
Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions in the inflammatory, cardiovascular, orthopedic and wound healing markets. The company operates its business through two segments: Therapeutics and Biosurgery segment. The Therapeutics segment focuses on developing biologic stem cell drug candidates from readily available and non-controversial sources. One of its products, Stromagen was used to treat breast cancer in clinical trials.
Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions in the inflammatory, cardiovascular, orthopedic and wound healing markets. The company operates its business through two segments: Therapeutics and Biosurgery segment. The Therapeutics segment focuses on developing biologic stem cell drug candidates from readily available and non-controversial sources. One of its products, Stromagen was used to treat breast cancer in clinical trials.
3
Country: USA | Funding: $50.2M
RecoveryOne is an innovator in mHealth solutions for patients recovering from orthopedic injuries.
RecoveryOne is an innovator in mHealth solutions for patients recovering from orthopedic injuries.
4
Country: USA | Funding: $40M
Regenexx focuses on developing breakthrough non-surgical options for people suffering from various orthopedic disorders. We have developed a patent-pending procedure that uses your own stem cells and blood growth factors to regenerate bone and cartilage.
Regenexx focuses on developing breakthrough non-surgical options for people suffering from various orthopedic disorders. We have developed a patent-pending procedure that uses your own stem cells and blood growth factors to regenerate bone and cartilage.
5
Country: USA | Funding: $35.3M
CIONIC is a technology company that builds a platform for human augmentation that powers people to transcend physical limitations.
CIONIC is a technology company that builds a platform for human augmentation that powers people to transcend physical limitations.
6
Country: USA | Funding: $25M
CurveBeam researches, designs and manufactures cone beam CT imaging equipment for the orthopedic specialties. CurveBeam is privately owned and operated.
CurveBeam researches, designs and manufactures cone beam CT imaging equipment for the orthopedic specialties. CurveBeam is privately owned and operated.
7
Country: UK | Funding: $16.3M
Gripable develops digital therapy tools, combining them with mobile games, and motivating physically impaired patients.
Gripable develops digital therapy tools, combining them with mobile games, and motivating physically impaired patients.
8
Country: Ireland | Funding: $14.8M
Intelligent Implants use wireless implantable electronics to stimulate, steer, and monitor bone growth.
Intelligent Implants use wireless implantable electronics to stimulate, steer, and monitor bone growth.
9
Country: USA | Funding: $11M
Limber is a digital home-exercise, remote monitoring, data analytics, and care navigation solution for musculoskeletal (MSK) conditions.
Limber is a digital home-exercise, remote monitoring, data analytics, and care navigation solution for musculoskeletal (MSK) conditions.
10
Country: New Zealand | Funding: $9M
SaaS for orthopedic surgery planning using the fusion of AI and biomechanics to improve patient outcomes and clinical efficiency.
SaaS for orthopedic surgery planning using the fusion of AI and biomechanics to improve patient outcomes and clinical efficiency.
11
Country: USA | Funding: $5M
Upswing Health provides a new way to conveniently deliver orthopedic care.
Upswing Health provides a new way to conveniently deliver orthopedic care.
12
Country: Singapore | Funding: $1.3M
Kinexcs: AI-driven digital therapy platform & wearables empowering mobility & better quality of life
Kinexcs: AI-driven digital therapy platform & wearables empowering mobility & better quality of life
13
Country: UK
Reflex Health develops an intuitive mobile app that offers AI-driven shoulder care solutions with recovery and progress monitoring features.
Reflex Health develops an intuitive mobile app that offers AI-driven shoulder care solutions with recovery and progress monitoring features.
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