Top 11 Opioid Addiction treatment startups

Updated: Nov 18, 2025
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These startups are developing novel Opioid Addiction treatments such as transcranial magnetic stimulation, wearable biosensors, digital therapeutics, virtual reality therapy, artificial intelligence for relapse prediction, pharmacogenomics.
1
axialHealthcare
Country: USA | Funding: $161.3M
axialHealthcare develops a platform for managing substance use disorder (SUD) patients
2
Quit Genius
Country: USA | Funding: $151.6M
Quit Genius uses technology to help people quit their addictions.
3
Pelago
Country: USA | Funding: $151.6M
Pelago is a virtual clinic that offers virtual substance use care for adults and teens.
4
Workit Health
Country: USA | Funding: $138.2M
Workit Health is a virtual clinic dedicated to medically-assisted treatment and online therapy for substance use disorder.
5
Eleanor Health
Country: USA | Funding: $115.1M
Eleanor Health provides comprehensive mental health and substance use disorder care in clinics, virtually, and in patient's homes.
6
Bicycle Health
Country: USA | Funding: $103.3M
Bicycle Health is a virtual addiction medicine clinic that helps treat opioid dependence or use disorder.
7
Boulder
Country: USA | Funding: $85.2M
Boulder connects patients seeking treatment for opioid use disorder to teams of addiction specialist, care coordinators and peer coaches through a telemedicine platform.
8
Boulder Care
Country: USA | Funding: $85.2M
Boulder is a telehealth provider of treatment and long-term support for people with substance use disorders
9
Ophelia
Country: USA | Funding: $67.7M
Ophelia offers medication and support for quitting opioids.
10
Scene Health
Country: USA | Funding: $36.4M
Scene Health focuses on solving the problem of medication non-adherence by leveraging people, science, and technology.
11
Sonara Health
Country: USA | Funding: $12.4M
Sonara is a healthcare technology company that develops telehealth platforms to aim to end the opioid epidemic.
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Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com