Top 6 Nanomedicine startups in USA
Nov 11, 2025
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1
Funding: $316.6M
T2 Biosystems is focused on developing innovative diagnostic products to improve patient health. With two FDA-cleared products targeting sepsis and a range of additional products in development, T2 Biosystems is an emerging leader in the field of in vitro diagnostics. Our initial development efforts utilizing T2MR target sepsis, hemostasis and Lyme disease, which are areas of significant unmet medical need in which existing therapies could be more effective with improved diagnostics.
T2 Biosystems is focused on developing innovative diagnostic products to improve patient health. With two FDA-cleared products targeting sepsis and a range of additional products in development, T2 Biosystems is an emerging leader in the field of in vitro diagnostics. Our initial development efforts utilizing T2MR target sepsis, hemostasis and Lyme disease, which are areas of significant unmet medical need in which existing therapies could be more effective with improved diagnostics.
2
Funding: $135.5M
The Cour particle platforms provide a novel and highly specific immune targeting capability which may be safely applied to severe inflammatory modulation, and immune (antigen) tolerization.
The Cour particle platforms provide a novel and highly specific immune targeting capability which may be safely applied to severe inflammatory modulation, and immune (antigen) tolerization.
3
Funding: $13.5M
Zylö Therapeutics has an innovative sustained-release drug-delivery system that uses patented hydrogel-derived nanoparticles
Zylö Therapeutics has an innovative sustained-release drug-delivery system that uses patented hydrogel-derived nanoparticles
4
Funding: $2.4M
Nanomedical Diagnostics is the first company to combine expertise in biology, nanotechnology, surface chemistry, engineering, and manufacturing to create practical and scaleable graphene biological field effect transistor (BioFET) products. Our ongoing mission is applying our cutting-edge capabilities to produce affordable diagnostic and monitoring platforms that deliver accurate, timely health information and improve patient outcomes and lives.
Nanomedical Diagnostics is the first company to combine expertise in biology, nanotechnology, surface chemistry, engineering, and manufacturing to create practical and scaleable graphene biological field effect transistor (BioFET) products. Our ongoing mission is applying our cutting-edge capabilities to produce affordable diagnostic and monitoring platforms that deliver accurate, timely health information and improve patient outcomes and lives.
5
Funding: $4.6M
Helex is revolutionizing genomic medicine and advances in treating genetic kidney diseases. It designed lipid nanoparticle technology for targeted drug delivery and an intelligent drug design platform that enables de-risked, scalable and affordable therapeutics. Therapeutic payloads are directed to specific organs and cells beyond the liver filter. The technology is said to minimize immune response and eliminate the risk of insertional mutagenesis linked with viral vectors. Also it has greater scalability than viral vectors due to their simpler production process.
Helex is revolutionizing genomic medicine and advances in treating genetic kidney diseases. It designed lipid nanoparticle technology for targeted drug delivery and an intelligent drug design platform that enables de-risked, scalable and affordable therapeutics. Therapeutic payloads are directed to specific organs and cells beyond the liver filter. The technology is said to minimize immune response and eliminate the risk of insertional mutagenesis linked with viral vectors. Also it has greater scalability than viral vectors due to their simpler production process.
6
NuVascular Technologies, Inc. is developing the next-generation of medical devices that will specifically treat patients suffering from end-stage renal (kidney) disease with the goal of helping patients live better and longer lives.
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