Top 190 Mental Health startups

Oct 02, 2025 | By Jason Kwon

These startups develop new Mental Health technologies, like telemedicine apps, virtual reality systems for rehabilitation, mental health management apps, electromagnetic brain stimulation...
1
Country: UK | Funding: $11.5M
PsyOmics develops proteomic diagnostics to improve early diagnosis and treatment outcomes for those with neuropsychiatric disorders.
2
Country: USA | Funding: $1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
3
Country: USA | Funding: $910.1M
Lyra is transforming mental health care by creating a frictionless experience for members, providers, and employers. Using technology and data, we connect companies and their employees to mental health providers and treatments that work.
4
Country: USA | Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
5
Country: USA | Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
6
Country: USA | Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
7
Country: USA | Funding: $391.4M
Neuronetics has pioneered and refined the NeuroStar TMS Therapy system. This non-invasive, non-systemic treatment for depression uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions. NeuroStar TMS Therapy is a safe and effective outpatient procedure, performed in a physician's office with each treatment lasting about 37 minutes daily for four to six weeks.
8
Country: USA | Funding: $325.5M
Headway is building a new mental healthcare system that everyone can access.
9
Country: UK | Funding: $271.2M
COMPASS Pathways is advancing the drug, the active ingredient in magic mushrooms, for use in people with treatment-resistant depression.
10
Country: USA | Funding: $270.9M
Quartet is a technology company improving behavioral health delivery for patients, providers, and payers.
11
Country: USA | Funding: $242M
Talkiatry is a leading technology enabled mental healthcare provider that delivers high-quality psychiatric care via telehealth or in-person
12
Country: USA | Funding: $220.5M
Alma is a membership-based network for mental health care providers.
13
Country: USA | Funding: $219M
Brightline is a med-tech company that provides behavioral healthcare services for children and their families.
14
Country: USA | Funding: $218M
Calm is working to bring the amazing benefits of meditation to a busy world. Calm operates an online portal which allows busy and information loaded web workers to reduce stress.
15
Country: USA | Funding: $216.8M
Cognito Therapeutics is a neurotechnology company that is developing disease-modifying treatments for CNS illnesses.
16
Country: USA | Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
17
Country: USA | Funding: $183M
SonderMind Wellness Centers is a franchisor of community centers for behavioral health providers.
18
Country: USA | Funding: $178M
Grow Therapy helps therapists easily start and grow thriving insurance-accepting practices, giving them the administrative and business tools, peer community support, and pipeline of referrals they need to make their lives better.
19
Country: USA | Funding: $167.4M
Modern Health is a mental well-being platform for innovative companies that want to reduce burnout and prevent turnover.
20
Country: USA | Funding: $135.1M
Big Health operates a digital healthcare portal used to offer behavioral programs for mental health issues.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com