Top 166 Mental Health startups

Updated: Nov 18, 2025
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These startups develop new Mental Health technologies, like telemedicine apps, virtual reality systems for rehabilitation, mental health management apps, electromagnetic brain stimulation...
1
Click Therapeutics
Country: USA | Funding: $1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
2
Lyra Health
Country: USA | Funding: $910.1M
Lyra is transforming mental health care by creating a frictionless experience for members, providers, and employers. Using technology and data, we connect companies and their employees to mental health providers and treatments that work.
3
Cerebral
Country: USA | Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
4
Spring Health
Country: USA | Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
5
Neuronetics
Country: USA | Funding: $451.4M
Neuronetics has pioneered and refined the NeuroStar TMS Therapy system. This non-invasive, non-systemic treatment for depression uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions. NeuroStar TMS Therapy is a safe and effective outpatient procedure, performed in a physician's office with each treatment lasting about 37 minutes daily for four to six weeks.
6
Compass Pathways
Country: UK | Funding: $421.2M
COMPASS Pathways is advancing the drug, the active ingredient in magic mushrooms, for use in people with treatment-resistant depression.
7
Talkspace
Country: USA | Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
8
Headway
Country: USA | Funding: $325.5M
Headway is building a new mental healthcare system that everyone can access.
9
Quartet Health
Country: USA | Funding: $270.9M
Quartet is a technology company improving behavioral health delivery for patients, providers, and payers.
10
Talkiatry
Country: USA | Funding: $242M
Talkiatry is a leading technology enabled mental healthcare provider that delivers high-quality psychiatric care via telehealth or in-person
11
Alma
Country: USA | Funding: $220.5M
Alma is a membership-based network for mental health care providers.
12
Brightline
Country: USA | Funding: $219M
Brightline is a med-tech company that provides behavioral healthcare services for children and their families.
13
Calm
Country: USA | Funding: $218M
Calm is working to bring the amazing benefits of meditation to a busy world. Calm operates an online portal which allows busy and information loaded web workers to reduce stress.
14
Cognito Therapeutics
Country: USA | Funding: $216.8M
Cognito Therapeutics is a neurotechnology company that is developing disease-modifying treatments for CNS illnesses.
15
Lark Health
Country: USA | Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
16
SonderMind
Country: USA | Funding: $183M
SonderMind Wellness Centers is a franchisor of community centers for behavioral health providers.
17
Grow Therapy
Country: USA | Funding: $178M
Grow Therapy helps therapists easily start and grow thriving insurance-accepting practices, giving them the administrative and business tools, peer community support, and pipeline of referrals they need to make their lives better.
18
Modern Health
Country: USA | Funding: $167.4M
Modern Health is a mental well-being platform for innovative companies that want to reduce burnout and prevent turnover.
19
Big Health
Country: USA | Funding: $135.1M
Big Health operates a digital healthcare portal used to offer behavioral programs for mental health issues.
20
Eleos Health
Country: USA | Funding: $128M
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com