Top 18 Hepatitis treatment startups

Oct 02, 2025 | By Jason Kwon

These startups develop new diagnostics and treatment technologies for Hepatitis, like gene editing therapies, direct-acting antiviral drugs, non-invasive liver fibrosis testing, point-of-care testing devices, HCV genotyping assays, CRISPR-based antiviral treatments
1
Country: USA | Funding: $505.6M
Aligos Therapeutics is discovering and developing new classes of molecules that interact directly with disease-causing modalities such as viral encoded proteins and nucleic acids, as well as oncogenes and their resultant proteins in the case of their cancer indications. The company is also pursuing novel therapeutic agents aimed at activation of the patients immune system, to create lasting benefits for the diseases that cause significant morbidity and mortality.
2
Country: USA | Funding: $1.6B
Arrowhead Research is focused on developing, commercializing, and licensing a range of nanotechnology products and applications.
3
Country: USA | Funding: $908.6M
Vir Biotechnology brings together cutting-edge innovations with scientific expertise and management.
4
Country: USA | Funding: $765M
VBI Vaccines is a biopharmaceutical company developing novel technologies that seek to expand vaccine protection in large underserved markets. VBI’s eVLP vaccine platform allows for the design of enveloped virus-like particle vaccines that closely mimic the target virus.
5
Country: USA | Funding: $498.5M
Terns Pharmaceuticals is a biopharmaceutical company that focuses on discovering therapies that will improve the global nonalcoholic steatohepatitis (NASH) burden.
6
Country: USA | Funding: $290M
Rivus Pharmaceuticals is dedicated to improving metabolic health by developing controlled metabolic accelerators (CMAs) that treat metabolic disorders, including the tricky nonalcoholic steatohepatitis (NASH), cardio-metabolic diseases and obesity, via weight loss.
7
Country: USA | Funding: $265.2M
Precision BioSciences is a genome editing company dedicated to improving life. Our team seeks to solve – not just treat, but solve – significant problems in oncology, genetic disease, agriculture, and beyond via its proprietary ARCUS genome editing platform.
8
Country: USA | Funding: $200.4M
Antios Therapeutics is a biopharmaceutical company developing innovative therapies for viral diseases.
9
Country: Netherlands | Funding: $149.4M
NorthSea Therapeutics is a biotech company developing first-in class, oral, structurally-engineered lipid therapeutics targeting metabolic, inflammatory and fibrotic diseases. The SEFA technology has generated pipeline candidates with a broad array of inter- and independent biological effects, improving dyslipidemia, insulin resistance, hepatic inflammation and fibrosis in diverse models.
10
Country: France | Funding: €103.5M
ENYO Pharma is a clinical stage Biotech with a unique drug discovery engine inspired by viruses. In particular it develops drug for Chronic Hepatitis B.
11
Country: China | Funding: $96.3M
Sinovac Biotech is a China-based biopharmaceutical company that focuses on research, development, manufacturing and commercialization of vaccines that protect against human infectious diseases including hepatitis A and B, seasonal influenza, H5N1 pandemic influenza (avian flu), H1N1 influenza (swine flu) ...
12
Country: China | Funding: $83M
Drug Farm creates a pipeline led by a treatment for hepatitis B infection.
13
Country: USA | Funding: $34.8M
Aethlon Medical creates immunotherapeutic devices to combat infectious disease and cancer.
14
Country: USA | Funding: $11.4M
CaroGen Corporation is an immunotherapy company employing a virus-like vesicle (VLV) platform technology. CaroGen develops vaccine candidates targeting hepatitis B and C, and other viral agents.
15
Country: USA | Funding: $3M
Chromis Therapeutics develops curative treatments for chronic HBV infection, based on its advanced proprietary drug design and discovery platform.
16
Country: Australia
Vaxine is focused on development of innovative vaccine technologies. Vaxine’s human candidates include vaccines against seasonal and pandemic influenza, hepatitis B, Japanese encephalitis, West Nile Virus, malaria, rabies, and allergy.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com