Top 44 Health Gadget startups in USA
Apr 22, 2026
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15
1
Funding: $298.3M
Cala Health is a medical technology company pioneering a new class of electrical medicine called neuroperipheral therapy. Neuroperipheral therapy has the potential to address chronic disease by externally stimulating peripheral nerves with body-worn electronics. Cala Health is bringing together experts in neuroscience, consumer electronics, and medical devices to develop accessible therapies that treat chronic disease non-invasively.
Cala Health is a medical technology company pioneering a new class of electrical medicine called neuroperipheral therapy. Neuroperipheral therapy has the potential to address chronic disease by externally stimulating peripheral nerves with body-worn electronics. Cala Health is bringing together experts in neuroscience, consumer electronics, and medical devices to develop accessible therapies that treat chronic disease non-invasively.
2
Funding: $312.1M
Eight Sleep is a sleep fitness company that leverages personal biometrics to restore individuals to their peak energy levels each morning.
Eight Sleep is a sleep fitness company that leverages personal biometrics to restore individuals to their peak energy levels each morning.
3
Funding: $352M
Enable Injections produces wearable delivery devices for injectible drugs. The Enable Injections products can deliver drugs directly from standard vials supplied by all pharmaceutical companies, can reconstitute powdered drugs into liquids as a part of the injection procedure, can inject very viscous drugs, and can inject up to 20 ml. Such products are called bolus injection systems.
Enable Injections produces wearable delivery devices for injectible drugs. The Enable Injections products can deliver drugs directly from standard vials supplied by all pharmaceutical companies, can reconstitute powdered drugs into liquids as a part of the injection procedure, can inject very viscous drugs, and can inject up to 20 ml. Such products are called bolus injection systems.
4
Funding: $605.6M
Butterfly Network operates at the cutting edge of multiple engineering and scientific disciplines and develops smartphone-connected ultrasound
Butterfly Network operates at the cutting edge of multiple engineering and scientific disciplines and develops smartphone-connected ultrasound
5
Funding: $337M
Exo is pioneering a high-performance handheld ultrasound platform and AI for imaging and therapeutic applications.
Exo is pioneering a high-performance handheld ultrasound platform and AI for imaging and therapeutic applications.
6
Funding: $301M
Glooko delivers a unified platform for diabetes management. We strive to improve health outcomes for people with diabetes and reduce the costs associated with diabetes population management. Glooko is dedicated to bringing innovation to diabetes management around the world.
Glooko delivers a unified platform for diabetes management. We strive to improve health outcomes for people with diabetes and reduce the costs associated with diabetes population management. Glooko is dedicated to bringing innovation to diabetes management around the world.
7
Funding: $220.5M
Ceribell is focused on making electroencephalography (EEG) widely accessible, more efficient, and more cost-effective
Ceribell is focused on making electroencephalography (EEG) widely accessible, more efficient, and more cost-effective
8
Funding: $216.8M
Cognito is developing a therapeutic device, Spectris, which can be prescribed by doctors and used by patients at home to treat Alzheimer's disease by stimulating coordinated neural activity through non-invasive visual and auditory stimulation. The device is designed as a full-size headphones. The pivotal clinical study, which is evaluating Spectris AD therapy for Alzheimer's disease, is currently underway, and the company is preparing to submit an application to the FDA.
Cognito is developing a therapeutic device, Spectris, which can be prescribed by doctors and used by patients at home to treat Alzheimer's disease by stimulating coordinated neural activity through non-invasive visual and auditory stimulation. The device is designed as a full-size headphones. The pivotal clinical study, which is evaluating Spectris AD therapy for Alzheimer's disease, is currently underway, and the company is preparing to submit an application to the FDA.
10
Funding: $173.2M
Eko Health is a digital health company providing digital stethoscopes and an AI detection platform for diagnosing heart and lung diseases.
Eko Health is a digital health company providing digital stethoscopes and an AI detection platform for diagnosing heart and lung diseases.
11
Funding: $173.2M
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
12
Funding: $154.3M
AliveCor is a leading FDA-cleared mobile heart solution that helps save lives, save money, and bring healthcare into the 21st century.
AliveCor is a leading FDA-cleared mobile heart solution that helps save lives, save money, and bring healthcare into the 21st century.
13
Funding: $151.4M
InfoBionic develops MoMe System, a patient monitoring platform that allows physicians to accurately diagnose and treat patients.
InfoBionic develops MoMe System, a patient monitoring platform that allows physicians to accurately diagnose and treat patients.
14
Funding: $98.3M
Podimetrics is a care management company with the leading solution to help prevent diabetic foot ulcers.
Podimetrics is a care management company with the leading solution to help prevent diabetic foot ulcers.
15
Funding: $98.1M
MedMinder Systems provides services that simplify medication management and improve medication adherence.
MedMinder Systems provides services that simplify medication management and improve medication adherence.
16
Funding: $89.9M
Profusa’s mission is to make our body’s chemistry easily accessible to improve health and wellness. We are dedicated to becoming a leader in the development of real-time biosensors that provide unprecedented insights into our overall health status.
Profusa’s mission is to make our body’s chemistry easily accessible to improve health and wellness. We are dedicated to becoming a leader in the development of real-time biosensors that provide unprecedented insights into our overall health status.
17
Funding: $82.3M
Renovia is the maker of an FDA-cleared, app-based system for pelvic floor disorder management and therapy
Renovia is the maker of an FDA-cleared, app-based system for pelvic floor disorder management and therapy
18
Funding: $75.8M
eNeura, a privately held medical technology company, is pioneering the use of portable, non-invasive Transcranial Magnetic Stimulation (TMS) devices for treatment of migraine. Prescribed by physicians but designed for patient use, it is the first truly portable, convenient TMS product that will allow migraine patients to administer treatment as needed—at home, in the office or on the go.
eNeura, a privately held medical technology company, is pioneering the use of portable, non-invasive Transcranial Magnetic Stimulation (TMS) devices for treatment of migraine. Prescribed by physicians but designed for patient use, it is the first truly portable, convenient TMS product that will allow migraine patients to administer treatment as needed—at home, in the office or on the go.
19
Funding: $57M
EyeQue is a maker of at home visual acuity tests. Dedicated to inspiring people to learn about & care for their eyes by putting affordable, accurate vision tests directly into their hands.
EyeQue is a maker of at home visual acuity tests. Dedicated to inspiring people to learn about & care for their eyes by putting affordable, accurate vision tests directly into their hands.
20
Funding: $56.3M
Heart Health Intelligence creates heart data collecting toilet seat, reducing the cost of heart failure through seamless in-home monitoring.
Heart Health Intelligence creates heart data collecting toilet seat, reducing the cost of heart failure through seamless in-home monitoring.
21
Funding: $54.4M
Zeto is transforming EEG for hospitals with a wireless, zero-prep, dry electrode headset backed by a state-of-the-art cloud platform
Zeto is transforming EEG for hospitals with a wireless, zero-prep, dry electrode headset backed by a state-of-the-art cloud platform
22
Funding: $48.7M
CarePredict is an AI Elder care platform that helps seniors live independently, economically and longer
CarePredict is an AI Elder care platform that helps seniors live independently, economically and longer
23
Funding: $39.8M
iBeat develops smartwatch that continually monitors your heart rate, oxygen levels, and blood flow for potential life-threatening emergencies.
iBeat develops smartwatch that continually monitors your heart rate, oxygen levels, and blood flow for potential life-threatening emergencies.
24
Funding: $31.3M
WearLinq produces wearable devices for health monitoring and diagnostics, in particular wireless 6-lead clinical ECG monitor and monitor eWave. It pairs with user's phone, transmitting real-time data and reports for up to 48 hours to doctors. The company claims the wireless monitor can last more than five days on a single charge. The device can help detect arrhythmias, but the company plans to expand its use in the future. WearLinq already received FDA clearance for the device to continuously monitor cardiac activity in individuals who may be asymptomatic or experience transient symptoms such as syncope, palpitations, dizziness, shortness of breath, lightheadedness, weakness, fatigue or anxiety.
WearLinq produces wearable devices for health monitoring and diagnostics, in particular wireless 6-lead clinical ECG monitor and monitor eWave. It pairs with user's phone, transmitting real-time data and reports for up to 48 hours to doctors. The company claims the wireless monitor can last more than five days on a single charge. The device can help detect arrhythmias, but the company plans to expand its use in the future. WearLinq already received FDA clearance for the device to continuously monitor cardiac activity in individuals who may be asymptomatic or experience transient symptoms such as syncope, palpitations, dizziness, shortness of breath, lightheadedness, weakness, fatigue or anxiety.
25
Funding: $29M
Bloomlife is committed to accelerating long overdue advancements to improve the health of moms and babies. By delivering an unmatched combination of technology, data science, and medical expertise we help women and clinicians get answers they can trust.
Bloomlife is committed to accelerating long overdue advancements to improve the health of moms and babies. By delivering an unmatched combination of technology, data science, and medical expertise we help women and clinicians get answers they can trust.
27
Funding: $23.6M
Cabinet Health offers refillable and compostable pill bottles and packaging
Cabinet Health offers refillable and compostable pill bottles and packaging
28
Funding: $22M
Tivic Health is a bioelectronic therapeutics company. We translate neuroscience into consumer-friendly medical devices, expanding the role of bioelectronic therapies in the healthcare ecosystem.
Tivic Health is a bioelectronic therapeutics company. We translate neuroscience into consumer-friendly medical devices, expanding the role of bioelectronic therapies in the healthcare ecosystem.
29
Funding: $15M
Proclaim develops personalized automated oral care system. It’s connected to a hydro station so that it can pulse 60 jets of pressurized water into your mouth over the course of seven seconds.
Proclaim develops personalized automated oral care system. It’s connected to a hydro station so that it can pulse 60 jets of pressurized water into your mouth over the course of seven seconds.
30
Funding: $15M
Iota Biosciences develops millimeter-sized, ultrasonic-powered bioelectronic devices also known as “neural dust” that can interface directly with the central nervous system. They empower doctors to safely get closer than ever to the internal causes of disease. Neural dust can be implanted practically anywhere in the body to gather precise data or to directly stimulate nerves.
Iota Biosciences develops millimeter-sized, ultrasonic-powered bioelectronic devices also known as “neural dust” that can interface directly with the central nervous system. They empower doctors to safely get closer than ever to the internal causes of disease. Neural dust can be implanted practically anywhere in the body to gather precise data or to directly stimulate nerves.
31
Funding: $14.2M
Sense Neuro Diagnostics is a developer of non-invasive medical devices for neurological conditions.
Sense Neuro Diagnostics is a developer of non-invasive medical devices for neurological conditions.
32
Funding: $13.8M
Sentio is a behavioral health startup offering an emotion-sensing wearable Feel that provides continuous monitoring and real-time personalized interventions for individuals that suffer from anxiety and depression.
Sentio is a behavioral health startup offering an emotion-sensing wearable Feel that provides continuous monitoring and real-time personalized interventions for individuals that suffer from anxiety and depression.
33
Funding: $12.5M
OOVA is a fertility diagnostic company that brings the accuracy of a clinic into your own home.
OOVA is a fertility diagnostic company that brings the accuracy of a clinic into your own home.
34
Funding: $11.5M
CareTaker develops the worlds most wireless innovative patient monitor.
CareTaker develops the worlds most wireless innovative patient monitor.
35
Funding: $12M
HERO is a revolutionary device and companion, improving your adherence to your vitamins and medications.
HERO is a revolutionary device and companion, improving your adherence to your vitamins and medications.
36
Funding: $11M
Kegg is a two-in-one device that combines fertility tracking with pelvic floor exercising.
Kegg is a two-in-one device that combines fertility tracking with pelvic floor exercising.
37
Funding: $10M
StimScience manufactures and provides electronic sleep aid headband for neuroscience.
StimScience manufactures and provides electronic sleep aid headband for neuroscience.
39
Funding: $7M
Cradlewise offers a smart cradle with responsive rocking and integrated contactless baby monitoring.
Cradlewise offers a smart cradle with responsive rocking and integrated contactless baby monitoring.
40
Funding: $5.6M
Allergy Amulet is the world’s smallest and fastest consumer food allergen sensor, testing for common allergenic ingredients in seconds.
Allergy Amulet is the world’s smallest and fastest consumer food allergen sensor, testing for common allergenic ingredients in seconds.
41
Funding: $5.5M
Oska Wellness is committed to developing health and wellness technology-driven products.
Oska Wellness is committed to developing health and wellness technology-driven products.
42
Funding: $3.7M
Keyto's platform measures biomarkers in a user's breath to gauge the state of their metabolism.
Keyto's platform measures biomarkers in a user's breath to gauge the state of their metabolism.
43
Funding: $120K
A bioinformatics company offering a unique platform for crowd-sourced brain research. It leverages cloud computing, big data and mobile technology to offer valuable personal insights and accelerate brain research globally.
A bioinformatics company offering a unique platform for crowd-sourced brain research. It leverages cloud computing, big data and mobile technology to offer valuable personal insights and accelerate brain research globally.
44
Medical Edge Solutions produces advanced medical equipment tailored to healthcare professionals’ needs. Its products include cutting-edge diagnostic and vestibular testing tools, the TM Flow System for TMJ disorder care, portable C-arm X-ray machines for flexible imaging, and knee therapy machines for optimized rehabilitation.
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