Top 20 Health Gadget startups in USA

Oct 14, 2025 | By Jason Kwon

1
Funding: $337M
Exo is pioneering a high-performance handheld ultrasound platform and AI for imaging and therapeutic applications.
2
Funding: $605.6M
Butterfly Network operates at the cutting edge of multiple engineering and scientific disciplines and develops smartphone-connected ultrasound
3
Funding: $347M
Enable Injections produces wearable delivery devices for injectible drugs. The Enable Injections products can deliver drugs directly from standard vials supplied by all pharmaceutical companies, can reconstitute powdered drugs into liquids as a part of the injection procedure, can inject very viscous drugs, and can inject up to 20 ml. Such products are called bolus injection systems.
4
Funding: $301M
Glooko delivers a unified platform for diabetes management. We strive to improve health outcomes for people with diabetes and reduce the costs associated with diabetes population management. Glooko is dedicated to bringing innovation to diabetes management around the world.
5
Funding: $262.1M
Eight Sleep is a sleep fitness company that leverages personal biometrics to restore individuals to their peak energy levels each morning.
6
Funding: $220.5M
Ceribell is focused on making electroencephalography (EEG) widely accessible, more efficient, and more cost-effective
7
Funding: $216.8M
Cognito Therapeutics is a neurotechnology company that is developing disease-modifying treatments for CNS illnesses.
8
Funding: $198.3M
Cala Health is a medical technology company pioneering a new class of electrical medicine called neuroperipheral therapy. Neuroperipheral therapy has the potential to address chronic disease by externally stimulating peripheral nerves with body-worn electronics. Cala Health is bringing together experts in neuroscience, consumer electronics, and medical devices to develop accessible therapies that treat chronic disease non-invasively.
9
Funding: $177.7M
quip designs and delivers oral care products, advice, and services.
10
Funding: $173.2M
Eko Health is a digital health company providing digital stethoscopes and an AI detection platform for diagnosing heart and lung diseases.
11
Funding: $173.2M
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
12
Funding: $154.3M
AliveCor is a leading FDA-cleared mobile heart solution that helps save lives, save money, and bring healthcare into the 21st century.
13
Funding: $151.4M
InfoBionic develops MoMe System, a patient monitoring platform that allows physicians to accurately diagnose and treat patients.
14
Funding: $98.3M
Podimetrics is a care management company with the leading solution to help prevent diabetic foot ulcers.
15
Funding: $98.1M
MedMinder Systems provides services that simplify medication management and improve medication adherence.
16
Funding: $89.9M
Profusa’s mission is to make our body’s chemistry easily accessible to improve health and wellness. We are dedicated to becoming a leader in the development of real-time biosensors that provide unprecedented insights into our overall health status.
17
Funding: $82.3M
Renovia is the maker of an FDA-cleared, app-based system for pelvic floor disorder management and therapy
18
Funding: $77.2M
AWAK develops wearable dialysis machines that operate and function like a normal kidney, for continuous dialysis.
19
Funding: $75.8M
eNeura, a privately held medical technology company, is pioneering the use of portable, non-invasive Transcranial Magnetic Stimulation (TMS) devices for treatment of migraine. Prescribed by physicians but designed for patient use, it is the first truly portable, convenient TMS product that will allow migraine patients to administer treatment as needed—at home, in the office or on the go.
20
Funding: $57M
EyeQue is a maker of at home visual acuity tests. Dedicated to inspiring people to learn about & care for their eyes by putting affordable, accurate vision tests directly into their hands.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com