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Top 19 Cystic fibrosis treatment startups
Oct 25, 2025 | By Jason Kwon | 19 |
These startups develop new diagnostics and treatment technologies for Cystic fibrosis, like genome analyses, lung function monitoring devices, wearable biosensors, gene therapy, new drugs...
1
Country: France | Funding: $315.9M
Inventiva is a clinical stage biopharmaceutical company with an expertise in fibrosis, oncology and orphan diseases. We are focussing on diseases with a high unmet medical need where either no treatments are available, such as NASH and Systemic Sclerosis, or the current standard of care leaves important manifestations of the diseases unaffected, as it is the case in many lysosomal storage diseases.
Inventiva is a clinical stage biopharmaceutical company with an expertise in fibrosis, oncology and orphan diseases. We are focussing on diseases with a high unmet medical need where either no treatments are available, such as NASH and Systemic Sclerosis, or the current standard of care leaves important manifestations of the diseases unaffected, as it is the case in many lysosomal storage diseases.
2
Country: USA | Funding: $292M
Sionna’s batch of small molecules will be the first to fully restore function to the cystic fibrosis transmembrane conductance regulator (CFTR) protein
Sionna’s batch of small molecules will be the first to fully restore function to the cystic fibrosis transmembrane conductance regulator (CFTR) protein
3
Country: Denmark | Funding: $160.4M
Galecto develops galectin modulators for the treatment of severe diseases, including fibrosis and cancer. The company builds on more than 10 years of research into galectins and galectin modulators, which combined with a strong patent estate gives Galecto Biotech a unique platform.
Galecto develops galectin modulators for the treatment of severe diseases, including fibrosis and cancer. The company builds on more than 10 years of research into galectins and galectin modulators, which combined with a strong patent estate gives Galecto Biotech a unique platform.
4
Country: USA | Funding: $145.6M
Mediar is a pre-clinical stage biotechnology company developing therapeutics for the treatment of fibrosis.
Mediar is a pre-clinical stage biotechnology company developing therapeutics for the treatment of fibrosis.
5
Country: UK | Funding: £68.8M
Enterprise Therapeutics is a drug discovery company dedicated to the research and development of novel therapies for the treatment of respiratory diseases. In diseases such as cystic fibrosis, asthma and COPD the lungs become congested with mucus leading to difficulty in breathing. New disease modifying therapies that target the underlying mechanisms of mucus congestion will reduce the frequency of lung infections and improve patient quality of life.
Enterprise Therapeutics is a drug discovery company dedicated to the research and development of novel therapies for the treatment of respiratory diseases. In diseases such as cystic fibrosis, asthma and COPD the lungs become congested with mucus leading to difficulty in breathing. New disease modifying therapies that target the underlying mechanisms of mucus congestion will reduce the frequency of lung infections and improve patient quality of life.
6
Country: USA | Funding: $63M
Stablix Therapeutics, a biotechnology company pioneering the Targeted Protein Stabilization technologies that is used to cure cystic fibrosis and cancer
Stablix Therapeutics, a biotechnology company pioneering the Targeted Protein Stabilization technologies that is used to cure cystic fibrosis and cancer
7
Country: USA | Funding: $53.9M
Lung Therapeutics pursues innovative treatments for underserved, life-threatening lung conditions. Our therapies for Idiopathic Pulmonary Fibrosis and Loculated Pleural Effusion bring hope to patients whose only treatment options may be invasive surgery or costly and ineffective drugs. We aim to create better pharmaceutical treatment options for IPF, LPE, and other underserved lung conditions.
Lung Therapeutics pursues innovative treatments for underserved, life-threatening lung conditions. Our therapies for Idiopathic Pulmonary Fibrosis and Loculated Pleural Effusion bring hope to patients whose only treatment options may be invasive surgery or costly and ineffective drugs. We aim to create better pharmaceutical treatment options for IPF, LPE, and other underserved lung conditions.
8
Country: UK | Funding: $53.7M
Using Artificial Intelligence (AI), deep learning algorithms Brainomix team is bringing complete stroke imaging decision support solution to hospitals worldwide.
Using Artificial Intelligence (AI), deep learning algorithms Brainomix team is bringing complete stroke imaging decision support solution to hospitals worldwide.
9
Country: USA | Funding: $38M
Carbon Biosciences is a biotech company that engages in the novel parvovirus gene therapy.
Carbon Biosciences is a biotech company that engages in the novel parvovirus gene therapy.
10
Country: Sweden | Funding: $28.2M
NuvoAir combines hardware, software and data to improve lives of people suffering from respiratory conditions
NuvoAir combines hardware, software and data to improve lives of people suffering from respiratory conditions
11
Country: Germany | Funding: $4.7M
Our mission at Talee Bio is to change the course of cystic fibrosis and other genetic lung diseases by developing novel genetic treatments. Our gene therapy technologies are designed to overcome the barriers that have so far prevented effective genetic treatments for cystic fibrosis.
Our mission at Talee Bio is to change the course of cystic fibrosis and other genetic lung diseases by developing novel genetic treatments. Our gene therapy technologies are designed to overcome the barriers that have so far prevented effective genetic treatments for cystic fibrosis.
12
Country: USA | Funding: $1.8M
Deton is transforming the understanding and treatment of lung disease by providing complete and timely lung health information thru Aerosol Biopsy
Deton is transforming the understanding and treatment of lung disease by providing complete and timely lung health information thru Aerosol Biopsy
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