Serapha Bio

Updated: July 31, 2026
Founder - Rajeev Shah
Founder - Rajeev Shah
Country: USA | Funding: $138M (+)
Founded: 2026

Website: https://www.seraphabio.com/

Serapha Bio is a clinical-stage biotechnology company focused on developing a base-editing therapy for Alpha-1 Antitrypsin Deficiency. The company's main asset SERP-01 is being investigated as a potential treatment for alpha-1-antitrypsin deficiency, targets the SERPINA1 E342K mutation. Early clinical data on SERP-01 give hope that this is a potentially best-in-class base editing therapy that can restore AAT to physiologic levels in patients with the most severe form of this disease

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