Top 37 medical and healthcare startups in Seattle

Aug 07, 2026
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1
Vedana Therapeutics
Funding: $46M
Vedana Therapeutics is developing next-generation antibody therapies for migraine prevention. The biotech’s lead program is an anti-PACAP antibody, while its second program is a bispecific antibody targeting both PACAP and CGRP that is designed to treat patients who have not found relief with monotherapies. CGRP is a messenger protein in the nervous system that is released in excess during a migraine attack, causing blood vessels in the brain's outer lining to dilate and triggering severe inflammation and pain. PACAP is a neuropeptide that widens blood vessels and transmits pain signals.
2
Sana Biotechnology
Funding: $951.3M
Sana Biotechnology is a developer of engineered cells intended to be used as medicine for patients. It's deploying a platform that can repair and control genes in cells or replace any cell in the body.
3
Truveta
Funding: $515M
Truveta is a healthcare data platform that provides electronic health records data for scientific research. Truveta's language model primarily extracts data from unstructured notes generated during patient care. This includes treatment progress notes, nursing assessments, procedure/surgery reports, referrals, discharge summaries, imaging reports, and more. The language model generates clinical concepts by linking the notes to structured data, enabling robust research in a variety of therapeutic areas, including cardiovascular disease, metabolic disease, oncology, neurology, hepatology, pulmonology, and rare diseases.
4
Avalyn Pharma
Funding: $372.5M
Avalyn Pharma is a biopharma company developing therapies for the treatment of idiopathic pulmonary fibrosis and other respiratory diseases.
5
Umoja Biopharma
Funding: $363M
Umoja Biopharma is a biopharmaceutical company developing next-generation immunotherapies intended to combat cancer.
6
98point6
Funding: $299.3M
98point6 combines deep technology with the expertise of board-certified physicians to provide text-based primary care anytime, anywhere.
7
Impel Pharmaceuticals
Funding: $261.3M
Impel Pharmaceuticals has created FDA-approved nasal spray Trudhesa for the relief of acute migraine attacks with or without aura in adults. Trudhesa gently delivers dihydroergotamine mesylate - therapeutic agent, quickly into the bloodstream through the vascularized upper nasal space. It bypasses the intestines and potential absorption issues, providing rapid, long-lasting, and consistent relief. Impel also developed its proprietary Precision Olfactory Delivery drug delivery technology, which targets the vascularized upper nasal space. Its clinical studies have demonstrated rapid absorption and consistent bioavailability, as well as ease of use for patients, physicians, and caregivers.
8
Tune Therapeutics
Funding: $215M
Tune Therapeutics develops epigenomic controls that dial gene expression up or down to potentially thwart cancers, genetic diseases and aging.
9
Callio Therapeutics
Funding: $187M
Callio Therapeutics develops next-generation antibody-drug conjugates (ADCs) with multiple payloads. They feature differentiated payload and linker technologies, which enables targeted delivery of drug combinations to tumor cells to maximize therapeutic effects for cancer patients. The company's flagship program is an ADC targeting HER2 breast cancer. Callio is a spinoff of Singapore-based Hummingbird Bioscience, which shares the CEO with Callio.
10
GentiBio
Funding: $177M
GentiBio is a biotherapeutics company developing engineered regulatory T cells (EngTregs) programmed to treat autoimmune allergic diseases.
11
DexCare
Funding: $145M
DexCare provides a Platform-as-a-Service offering to manage health system capacity and demand across all lines of care.
12
Tasso
Funding: $135.6M
Tasso is revolutionizing diagnostics by creating technologies for blood sample collection that place the user at the center of process. Our wearable blood collection system, the HemoLinkTM, is being developed to improve the user experience as well as enable both healthcare consumers and providers with convenient access to reliable laboratory test results.
13
Aurion Biotech
Funding: $120M
Aurion Biotechnologies is on mission is to cure leading forms of blindness and transform the lives of millions of patients, by developing a platform of advanced therapies to treat ocular diseases.
14
Vera Whole Health
Funding: $95.5M
Vera Whole Health delivers primary care, acute care, and health coaching via on or near-site clinics.
15
Bonum Therapeutics
Funding: $93M
Bonum Therapeutics technology platform can be used to treat a variety of diseases, including oncology.
16
Proprio
Funding: $85.1M
Proprio uses machine learning, computer vision, and augmented reality user interfaces to improve the accuracy and efficiency of surgery.
17
Vilya
Funding: $71M
Vilya is a biotechnology company that plans to design novel artificial molecules with customized biologic-like properties that can hit difficult-to-drug therapeutic targets in a broad set of indications.
18
Immunexpress
Funding: $67M
Immunexpress, a molecular diagnostics company, developed a product pipeline to address the unmet clinical needs of sepsis patients, as well as the professional needs of clinicians, payers, and healthcare systems.
19
Xealth
Funding: $56.9M
Xealth enables healthcare teams to order digital content and services as easily as they do medications today.
20
Visus Therapeutics
Funding: $56M
Visus Therapeutics is a clinical-stage pharmaceutical company lighting the way to dramatically improve patient lives through the development of differentiated, best-in-class ophthalmic therapies.
21
Rippl
Funding: $55M
Rippl, a mental health organization, is committed to assisting seniors who suffer from dementia and other neurocognitive disorders.
22
Bardy Diagnostics
Funding: $46M
Bardy Diagnostics created a new, state-of-the-art heart monitor known as Carnation Ambulatory Monitor that can be worn comfortably and discreetly for up to 7 days. Unlike many other heart monitors, CAM™ can be worn during exercise or while showering. Its unique, narrow, hourglass shape makes it especially advantageous for the female anatomy.
23
Inipharm
Funding: $35M
Inipharm is building on novel insights and applying our chemistry expertise to develop therapies for patients with liver disease.
24
Oisin Biotechnologies
Funding: $32.1M
Oisín Biotechnologies' ground-breaking research and technology is demonstrating that the solution to mitigating the effects of age-related diseases is to address the damage created by the aging process itself.
25
Cloud Health Systems
Funding: $30M
Cloud Health Systems provides consultations and other health services to consumers, first focusing on metabolic health and obesity.
26
Talus Bioscience
Funding: $27.8M
Talus Bio is a drug discovery biotech startup that develops drugs targeting undruggable transcription factors using AI.
27
Motivity
Funding: $27M
Motivity provides clinical software solutions through insights, data mining and collection for the ABA and behavioral health industries.
28
Curi Bio
Funding: $20.4M
Curi Bio is integrating human iPSC-derived cells, tissue-specific biosystems, and AI-enabled data analytics of new therapeutics.
29
Firsthand
Funding: $120K
Since 1995, Firsthand has been creating interactive Virtual Reality applications for education, training, business, research and therapy. Our services include creative design, application development, immersive displays, and customized turnkey VR hardware systems.
30
Kevala
Funding: $16.1M
Kevala provides network and digital services intended for delivering flexibility, connectivity and confidence to healthcare's front line.
31
VillageReach
Funding: $8.7M
Save lives and improve health by increasing access to quality healthcare for the most underserved communities.
32
TransformativeMed
Funding: $7M
TransformativeMed is driving a revolution in health information technology by creating "Smart Health Apps.
33
Zocalo Health
Funding: $5.2M
Zócalo Health is a virtual healthcare service for Latino patients
34
Swizzle Fund
Funding: $5M
Swizzle Ventures is a venture capital firm that empowers women's health and wealth through pivotal life stages.
35
Genneve
Funding: $4.5M
genneve, a digital health company for women in midlife & menopause. genneve increases accessibility to information, health providers and community for women seeking relief for hormone-driven symptoms like hot flashes, insomnia, anxiety and loss of libido.
36
Exonicus
Funding: $3.6M
Exonicus is developing a trauma simulator for military medics
37
Dendreon
Dendreon was a biotechnology company produces immunotherapy for prostate cancer. Its cancer vaccine uses a patient’s own immune cells, which are collected, processed and infused back into the individual through an intravenous infusion that is completed in three cycles.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com