Top 53 medical and healthcare startups in San Diego

Last updated: May 09, 2024

1
Funding: $1.5B
Zogenix engages in the development and commercialization of products for the treatment of central nervous system disorders and pain.
2
Funding: $1.2B
TP Therapeutics is a clinical-stage biopharmaceutical company that is focusing on overcoming drug resistance in precision medicines for cancer and other diseases.
3
Funding: $1.1B
Crinetics Pharmaceuticals explores the inner life of GPCRs to discover and develop novel therapeutics targeting peptide hormone receptors for the treatment of rare endocrine disorders and endocrine-related cancers.
4
Funding: $999.6M
Cue Health develops and manufactures medical diagnostic products which are used in clinical and at-home settings.
5
Funding: $799M
Samumed is a leader in medical research and development for tissue-level regeneration. With our platform's origins in small molecule-based Wnt pathway modulation, we develop therapeutics to address a range of degenerative diseases, regenerative medicine and oncology.
6
Funding: $737.6M
Rakuten Aspyrian is developing tumor-targeted precision therapies based on its proprietary platform Photoimmunotherapy.
7
Funding: $480.9M
Regulus Therapeutics is a biopharmaceutical company involved in the R&D of high-impact medicines based on microRNAs.
8
Funding: $460.5M
Poseida Therapeutics utilizes best-in-class genome engineering capabilities to develop targeted lifesaving therapeutics.
9
Funding: $418M
RayzeBio is focused on improving outcomes for people with cancer by harnessing the power of targeted radioisotopes.
10
Funding: $340.5M
Human Longevity is the genomics-based, technology-driven company creating the world’s largest and most comprehensive database of whole genome, phenotype and clinical data. HLI is developing and applying large scale computing and machine learning to make novel discoveries to revolutionize the practice of medicine.
11
Funding: $340M
Capstan Therapeutics is advancing cell engineering to develop CAR-T therapeutics for a broad range of diseases.
12
Funding: $332M
ADARx Pharmaceuticals is a genetic medicine company focusing on the base editing of mRNA transcripts.
13
Funding: $264M
Aspen Neuroscience is a private biotechnology company that uses innovative genomic approaches combined with stem cell biology.
14
Funding: $260M
Neurocrine Biosciences engages in the discovery and development of drugs for the treatment of neurological and endocrine-related diseases.
15
Funding: $254.3M
Biolinq develops skin-applied electronic sensors. Finally, people with diabetes will have a better CGM experience that is not only more affordable, but also pain-free.
16
Funding: $237.5M
Escient Pharmaceuticals is a provider of bio-technical research and development services intended to focus in advancement of first-in-class G Protein-Coupled Receptor targeted drugs. The company's services focuses on offering therapies for neuro-immuno-inflammatory and autoreactive diseases
17
Funding: $235.5M
ViaCyte is a leader in the emerging field of regenerative medicine. ViaCyte's innovative product is based on the differentiation of stem cells into pancreatic beta cell precursors, with subcutaneous implantation in a retrievable and immune-protective encapsulation medical device. Once implanted, the precursor cells mature into endocrine cells that secrete insulin and other hormones in a regulated manner to control blood glucose levels. ViaCyte's goal is a product that can free patients with type 1 and type 2 diabetes from long-term insulin dependence.
18
Funding: $221M
Engrail Therapeutics is a developer of medicines to transform the lives of patients with life-limiting diseases of the nervous system.
19
Funding: $213.1M
Ansun BioPharma is a clinical stage biopharmaceutical company focused on the development of unique host-directed anti-viral
20
Funding: $198M
Artiva Biotherapeutics is an oncology company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.
21
Funding: $175M
Cortica provides neurological therapies for children with autism and other developmental differences.
22
Funding: $173M
Metacrine is an emerging biotech company focused on developing best-in-class therapies to benefit patients with liver, gastrointestinal, and metabolic diseases.
23
Funding: $165M
Plexium is a drug development startup that leverages techniques from various physical-science and computational disciplines.
24
Funding: $154.8M
Genalyte is guided by the vision of taking a single drop of blood, performing panels of tests and returning accurate and reproducible results within a few minutes.
25
Funding: $153M
Iambic Therapeutics is built on technologies for predicting protein-ligand structures, generating molecular designs and other drug discovery tasks. Using the technologies, Iambic claims it can accelerate drug discovery, pointing to the two years it took to take its lead project from program launch to IND to make its case.
26
Funding: $120M
Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras.
27
Funding: $112.3M
At Organovo, we design and create functional human tissues using our proprietary three-dimensional bioprinting technology. Our goal is to build living human tissues that are proven to function like native tissues. With reproducible 3D tissues that accurately represent human biology, we are enabling ground-breaking therapies by:
28
Funding: $109.7M
Equip is a virtual eating disorder treatment program
29
Funding: $85.9M
AnaptysBio is a therapeutic antibody product company and the leader in the use of somatic hypermutation, or SHM, for antibody discovery and optimization. SHM is the body's natural process for generating potent antibodies to fight disease.
30
Funding: $58.5M
Concert Health offers behavioral health services to primary care practices
31
Funding: $55.3M
Turquoise Health is a health tech company that simplifies administration to reduce the expense and complexity of healthcare.
32
Funding: $55M
Replay is a genome writing company reprogramming biology by writing and delivering big DNA.
33
Funding: $53.4M
AristaMD is a healthcare company that features a software platform that helps hospitals and practitioners on improving patient outcomes.
34
Funding: $52.6M
BetterNight is providing telehealth-based sleep solutions.
35
Funding: $40M
Creyon Bio is a drug development company engineering RNA-based medicines and their components.
36
Funding: $39M
Ocelot Bio brings new treatment options to patients with severe liver disease.
37
Funding: $31.9M
Companion Medical develops products to improve healthcare with easy-to-use medical devices that utilize state-of-the-art technologies. It has experiences in medical devices and critical systems development, and its team is positioned to introduce exciting new medical products that improve and facilitate patient care. The company’s initial products focus on providing improved care to insulin using Diabetics.
38
Funding: $30.1M
Aethlon Medical creates immunotherapeutic devices to combat infectious disease and cancer.
39
Funding: $27M
Data driven MSK solution for systems and payers who want to eliminate unnecessary surgery, lower opioid usage and drive higher outcomes.
40
Funding: $23M
Vessel is an at-home wellness tracker that helps in accessing, understanding, and optimizing health and wellness from the comfort of home.
41
Funding: $18M
Headlight is a mental health firm that aims to change the way mental health services are delivered.
42
Funding: $17.1M
Rejuvenate Bio develops genetherapy to fend off aging
43
Funding: $2.4M
Nanomedical Diagnostics is the first company to combine expertise in biology, nanotechnology, surface chemistry, engineering, and manufacturing to create practical and scaleable graphene biological field effect transistor (BioFET) products. Our ongoing mission is applying our cutting-edge capabilities to produce affordable diagnostic and monitoring platforms that deliver accurate, timely health information and improve patient outcomes and lives.
44
Angionetics is focused on the late-stage clinical development and commercialization of Generx, an angiogenic gene therapy product candidate designed for medical revascularization for the potential treatment of patients with myocardial ischemia and refractory angina due to advanced coronary artery disease.
45
Funding: $6.4M
Nanome helps scientists get up close with molecular structures in VR
46
Funding: $6M
Sleep Data develops virtual care platform BetterNight catered to people with sleep apnea, insomnia, anxiety, jet lag, stress and other sleep conditions.
47
Funding: $5.1M
Cari Health develops remote medication monitors that allow clinicians to precision dose and increase adherence to lifesaving therapeutics.
48
Iron Horse Therapeutics is developing treatments for amyotrophic lateral sclerosis (ALS) with compounds that modulate the activity of EphA4. Humans with EphA4 mutations that decrease its activity or reduced EphA4 expression levels exhibit prolonged survival and reduced disease severity. Similar results have been demonstrated in ALS mouse and rat animal models.
49
CureMetrix offers a next generation of medical image analysis for Mammography.
50
Funding: $3M
Chromis Therapeutics develops curative treatments for chronic HBV infection, based on its advanced proprietary drug design and discovery platform.