Top 21 medical and healthcare startups in Spain

Sep 17, 2025 | By Jason Kwon

1
Funding: $193.9M
Splice Bio is a biotech company developing gene therapies based on a platform that could bypass the cargo capacity of adeno-associated vectors (AAVs).
2
Funding: $180.8M
Impress is a developer of orthodontic technology that offers invisible aligners.
3
Funding: $143.9M
Minoryx Therapeutics offers pharmacological chaperones, which are small molecule drugs used for the treatment of genetic diseases.
4
Funding: $69.6M
QUIBIM is a biotech company dedicated to medical image processing and extraction of imaging biomarkers for the medical imaging workflows.
5
Funding: $65.6M
Overture Life is making In Vitro Fertilization (IVF) more accessible than ever. An embryology lab in a box that pushes IVF to a whole new level.
6
Funding: €44.1M
Koa Health is a digital wellbeing and therapeutics solutions combine the latest clinical research and breakthrough technologies.
7
Funding: $44.4M
Savana is a machine learning-based service that turns clinical notes into structured patient information for physicians and pharmacists
8
Funding: $39.9M
ifeel is the all-in-one emotional well-being platform for organisations and individuals.
9
Funding: €23.8M
Top Doctors is an online platform for identifying, interacting and booking e-consultations with medical specialists in private healthcare.
10
Funding: $15.8M
The most advanced and accurate sypmtom checker. The first artificial intelligent system clinically validated that is transforming healthcare for everyone.
11
Funding: €8.1M
60 million people in the world have lost walking ability. 17 million are children affected by a number of neurological diseases. While wheelchair bounded, they suffer from a number of physiological and psychological side effects. Their quality of life could be largely improved if walking could be repaired, restored or rehabilitated. Marsi Bionics works towards this goal.
12
Araclon Biotech is a company dedicated to the research and development of therapies and diagnostic methods to be applied to degenerative diseases, currently focusing on Alzheimer’s disease.
13
Funding: $11.6M
Devicare has developed Lit-Control - the most advanced, comprehensive and effective medical treatment for Kidney Stones. Lit-Control is a family of four innovative medical foods that have been formulated to treat and manage the nutritional needs of patients with each of the four major groups of Kidney Stones (i.e. calcium, uric acid, infectious and cytine stones). And in combination with these medical foods, Lit-Control also incorporates a ground-breaking digital therapeutic to ease the follow-up of these patients.
14
Funding: €7.7M
MediQuo develops 24-hour, 7-day-a-week medical chat application that gives doctors and health professionals the ability to manage online appointments, both for their own patients as well as for the users of the app.
15
Funding: €5.3M
Senniors provides home care services for older people and others who need support
16
Funding: €5.1M
Bionure Farma develops innovative therapies for the treatment of orphan ophthalmology diseases and multiple sclerosis.
17
Funding: €5M
iDoctus is a full-reference mobile app that helps Spanish physicians to make better clinical decisions.
18
Funding: $2M
KeyZell, is a company that has combined biotechnology with mathematics, to develop new solutions against the fight against cancer.
19
Funding: $1.1M
REGEMAT3D, a biotech company pioneer in the use of 3D printing for regenerative therapies.
20
Iakan Health develops AI technology to assist medical and research professionals in cancer treatment
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com