Top 73 medical and healthcare startups in Germany
Dec 01, 2025
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25
1
Funding: $2B
BioNTech is a global leader in mRNA-based immunotherapy. The company was the first to invent and commercialize a COVID-19 vaccine (in partnership with Pfizer). BioNTech is currently developing several personalized immunotherapeutic agents (vaccines) against cancer and infectious diseases, including melanoma, human papillomavirus, non-small cell lung cancer, tuberculosis and malaria. The company's flagship platform, FixVac, enables the creation of ready-to-use mRNA cancer vaccines that can be used off-shelf to a specific indication (fixed-dose vaccines). These vaccines are a fixed combination of unmutated tumor antigens encoded by mRNA, which are frequently expressed in certain types of cancer. The mRNA is delivered using a proprietary RNA-lipoplex delivery system, which is designed to enhance mRNA stability in the body and target antigen-presenting dendritic cells (DCs), the training grounds of our immune system.
BioNTech is a global leader in mRNA-based immunotherapy. The company was the first to invent and commercialize a COVID-19 vaccine (in partnership with Pfizer). BioNTech is currently developing several personalized immunotherapeutic agents (vaccines) against cancer and infectious diseases, including melanoma, human papillomavirus, non-small cell lung cancer, tuberculosis and malaria. The company's flagship platform, FixVac, enables the creation of ready-to-use mRNA cancer vaccines that can be used off-shelf to a specific indication (fixed-dose vaccines). These vaccines are a fixed combination of unmutated tumor antigens encoded by mRNA, which are frequently expressed in certain types of cancer. The mRNA is delivered using a proprietary RNA-lipoplex delivery system, which is designed to enhance mRNA stability in the body and target antigen-presenting dendritic cells (DCs), the training grounds of our immune system.
2
Funding: €508M
Tubulis produces uniquely matched antibody-drug conjugates with exceptional biophysical properties that have shown durable on-tumor delivery and long-lasting anti-tumor activity. Its P5 Conjugation Technology allows to quickly generate highly stable ADCs with chemical flexibility that provides the potential to develop truly differentiated ADCs. Leveraging this technology, the Tubutecan Platform allows stable, high DAR 8 conjugation of potent topoisomerase-I inhibitors with improved on-target delivery and decreased off-target toxicity – without compromising ADC properties. The company is developing a portfolio of ADCs that can target previously unreachable targeting molecules and carry novel payloads.
Tubulis produces uniquely matched antibody-drug conjugates with exceptional biophysical properties that have shown durable on-tumor delivery and long-lasting anti-tumor activity. Its P5 Conjugation Technology allows to quickly generate highly stable ADCs with chemical flexibility that provides the potential to develop truly differentiated ADCs. Leveraging this technology, the Tubutecan Platform allows stable, high DAR 8 conjugation of potent topoisomerase-I inhibitors with improved on-target delivery and decreased off-target toxicity – without compromising ADC properties. The company is developing a portfolio of ADCs that can target previously unreachable targeting molecules and carry novel payloads.
3
Funding: $2.1B
CureVac is a biopharmaceutical company specializing in the prophylactic and therapeutic application of messenger RNA.
CureVac is a biopharmaceutical company specializing in the prophylactic and therapeutic application of messenger RNA.
4
Funding: $748.1M
MorphoSys' mission is to make exceptional, innovative biopharmaceuticals to improve the lives of patients suffering from serious diseases. Our focus is on cancer.
MorphoSys' mission is to make exceptional, innovative biopharmaceuticals to improve the lives of patients suffering from serious diseases. Our focus is on cancer.
5
Funding: €275M
AMBOSS is a digital medical knowledge platform providing clinical content for decision-making.
AMBOSS is a digital medical knowledge platform providing clinical content for decision-making.
6
Funding: €275M
Amboss is improving healthcare by making medical knowledge universally accessible.
Amboss is improving healthcare by making medical knowledge universally accessible.
7
Funding: $197.4M
T-knife is a developer of T cell receptors intended for T cell therapy of cancer.
T-knife is a developer of T cell receptors intended for T cell therapy of cancer.
8
Funding: €185M
Neura Robotics develops cognitive robots that can be utilized in both industrial and daily settings.
Neura Robotics develops cognitive robots that can be utilized in both industrial and daily settings.
9
Funding: $189.5M
Ada Health is breaking new ground across medical reasoning and artificial intelligence. Ada is a personal health companion that uses AI and machine learning to help people to understand and manage their health. Designed by a team of 100 doctors, data scientists and engineers, Ada was launched with the mission to give everyone access to high quality, personalised health information and care.
Ada Health is breaking new ground across medical reasoning and artificial intelligence. Ada is a personal health companion that uses AI and machine learning to help people to understand and manage their health. Designed by a team of 100 doctors, data scientists and engineers, Ada was launched with the mission to give everyone access to high quality, personalised health information and care.
10
Funding: $134.7M
Sanity Group is a holistic European Cannabis company focusing on health, wellbeing, and scientific research.
Sanity Group is a holistic European Cannabis company focusing on health, wellbeing, and scientific research.
11
Funding: $125M
kaia is a digital therapeutics company focused on AI-powered management of chronic pain
kaia is a digital therapeutics company focused on AI-powered management of chronic pain
12
Funding: $119.3M
Wingcopter is a manufacturer of unmanned eVTOL fixed-wing aircrafts for commercial and humanitarian applications.
Wingcopter is a manufacturer of unmanned eVTOL fixed-wing aircrafts for commercial and humanitarian applications.
13
Funding: $101.4M
Avi Medical is a digital health care company that provides telemedicine services.
Avi Medical is a digital health care company that provides telemedicine services.
14
Funding: $85.7M
Enhancing healthcare supply chains with data-driven compliance solutions, worldwide.
Enhancing healthcare supply chains with data-driven compliance solutions, worldwide.
15
Funding: €80M
Cardior Pharmaceuticals discovers and develops medicines and therapeutics for the treatment and prevention of heart disease.
Cardior Pharmaceuticals discovers and develops medicines and therapeutics for the treatment and prevention of heart disease.
16
Funding: €77M
Smile2Impress is a Berlin-based Health-Tech Startup in the area of digital dentistry.
Smile2Impress is a Berlin-based Health-Tech Startup in the area of digital dentistry.
17
Funding: €72M
Medwing is a healthcare start-up that provides opportunities to work in the healthcare sector.
Medwing is a healthcare start-up that provides opportunities to work in the healthcare sector.
19
Funding: $70M
Freeletics promotes and increases physical fitness, strives for improved mental strength, willpower, and confidence - all vital components for shaping one's lifestyle according to individual desires and goals.
Freeletics promotes and increases physical fitness, strives for improved mental strength, willpower, and confidence - all vital components for shaping one's lifestyle according to individual desires and goals.
20
Funding: $61.7M
Wellster is the go-to solution for everyday consumer health. It builds digital clinics along the lifecycle of next gen. health consumers.
Wellster is the go-to solution for everyday consumer health. It builds digital clinics along the lifecycle of next gen. health consumers.
