Top 8 Sleep enhancement and Insomnia treatment startups in USA

Nov 16, 2025
1
Funding: $259.3M
Apnimed is a clinical-stage company dedicated to the discovery of novel pharmacologic therapies for sleep apnea and related disorders.
2
Funding: $262.1M
Eight Sleep is a sleep fitness company that leverages personal biometrics to restore individuals to their peak energy levels each morning.
3
Funding: $52.6M
BetterNight is providing telehealth-based sleep solutions.
4
Funding: $16.1M
Huckleberry pairs pediatric sleep experts with AI to create a custom sleep plan with your unique family in mind.
5
Funding: $10M
StimScience manufactures and provides electronic sleep aid headband for neuroscience.
6
Funding: $6M
Sleep Data develops virtual care platform BetterNight catered to people with sleep apnea, insomnia, anxiety, jet lag, stress and other sleep conditions.
7
Funding: $4.7M
Arcascope makes apps that utilize algorithms that track circadian rhythms and generates personalized recommendations.
8
Funding: $1.1M
NightWare is an application on an Apple Watch that helps people suffering from traumatic nightmares to get a more restful night's sleep. It is a wearable technology that learns your sleep patterns and customizes a treatment for each individual, interrupting nightmares so you can get an uninterrupted night's sleep.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com