Top 7 Skin Cancer and Melanoma treatment startups in USA

Oct 24, 2025 | By Jason Kwon

1
Funding: $1.6B
IOVANCE Biotherapeutics is focused on the development and commercialization of autologous cellular immunotherapies optimizing personalized, tumor-directed Tumor Infiltrating Lymphocytes (TIL)
2
Funding: $325M
Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
3
Funding: $259.9M
DermTech is the global leader in molecular dermatology, bringing precision medicine to the diagnosis and treatment of skin disease. We market and develop products that facilitate the early detection of skin cancers, assess inflammatory diseases, and customize drug treatments.
4
Funding: $35.9M
DermaSensor is developing a medical device that aims to detect the risk of skin cancer.
5
Funding: $25M
Sensus Healthcare is focused on developing proven non-invasive treatment for non-melanoma skin cancer.
6
Funding: $9.9M
BioVaxys is a clinical stage biotechnology company developing immunotherapeutic cancer vaccines targeting melanoma and ovarian cancer.
7
Funding: $3.4M
SkinIO is helping people prevent skin cancer by providing a service that allows them to regularly monitor their skin with the help of artificial intelligence and licensed dermatologists. Users can take photos with their smartphone of their skin and lesions, and upload them to a database through SkinIO’s app.
  See also:
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com