Top 15 Skin Cancer and Melanoma treatment startups

Updated: Dec 01, 2025
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These startups develop new melanoma/skin cancer treatments and diagnostics technologies, such as computer vision, immunotherapy, genome analytics, RNA-therapies.
1
BioNTech
Country: Germany | Funding: $2B
BioNTech is a global leader in mRNA-based immunotherapy. The company was the first to invent and commercialize a COVID-19 vaccine (in partnership with Pfizer). BioNTech is currently developing several personalized immunotherapeutic agents (vaccines) against cancer and infectious diseases, including melanoma, human papillomavirus, non-small cell lung cancer, tuberculosis and malaria. The company's flagship platform, FixVac, enables the creation of ready-to-use mRNA cancer vaccines that can be used off-shelf to a specific indication (fixed-dose vaccines). These vaccines are a fixed combination of unmutated tumor antigens encoded by mRNA, which are frequently expressed in certain types of cancer. The mRNA is delivered using a proprietary RNA-lipoplex delivery system, which is designed to enhance mRNA stability in the body and target antigen-presenting dendritic cells (DCs), the training grounds of our immune system.
2
CureVac
Country: Germany | Funding: $2.1B
CureVac is a biopharmaceutical company specializing in the prophylactic and therapeutic application of messenger RNA.
3
Iovance Biotherapeutics
Country: USA | Funding: $1.6B
IOVANCE Biotherapeutics is focused on the development and commercialization of autologous cellular immunotherapies optimizing personalized, tumor-directed Tumor Infiltrating Lymphocytes (TIL)
4
Obsidian Therapeutics
Country: USA | Funding: $325M
Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
5
DermTech
Country: USA | Funding: $259.9M
DermTech is the global leader in molecular dermatology, bringing precision medicine to the diagnosis and treatment of skin disease. We market and develop products that facilitate the early detection of skin cancers, assess inflammatory diseases, and customize drug treatments.
6
Juventas
Country: China | Funding: $101.6M
Juventas is a provider and developer of innovative immune cell therapeutic drugs.
7
DermaSensor
Country: USA | Funding: $35.9M
DermaSensor is developing a medical device that aims to detect the risk of skin cancer.
8
Skin Analytics
Country: UK | Funding: $31M
Skin Analytics uses artificial intelligence to screen for melanoma skin cancer.
9
Sensus Healthcare
Country: USA | Funding: $25M
Sensus Healthcare is focused on developing proven non-invasive treatment for non-melanoma skin cancer.
10
SkinVision
Country: Netherlands | Funding: $16.5M
SkinVision is a mobile app that allows you to understand your risk factors for skin cancer and keep track of your moles.
11
BioVaxys
Country: USA | Funding: $13.8M
BioVaxys is a clinical stage biotechnology company developing immunotherapeutic cancer vaccines targeting melanoma and ovarian cancer.
12
SkinIO
Country: USA | Funding: $3.4M
SkinIO is helping people prevent skin cancer by providing a service that allows them to regularly monitor their skin with the help of artificial intelligence and licensed dermatologists. Users can take photos with their smartphone of their skin and lesions, and upload them to a database through SkinIO’s app.
13
Skinive
Country: Netherlands | Funding: €1M
Skinive's goal is to provide personalized advice and prevent dangerous skin diseases among people.
14
Firstcheck
Country: New Zealand | Funding: NZ$1.5M
Firstcheck has created an app through which users can snap a few pictures of a mole they are concerned about, choose a dermatologist or skin specialist to review their case, and receive feedback within three days.
15
NOTA mole tracker
Country: Singapore
NOTA mole tracker is a device&app for mapping and checking moles at home. Early diagnosis of skin cancer/melanoma with bioimpedance.
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Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com