Top 6 Psoriasis treatment startups in USA

Jun 24, 2026
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1
Nimbus Therapeutics
Funding: $637M
Nimbus Therapeutics develops highly selective and potent small molecule drugs aimed at suppressing known factors that cause serious diseases, including metabolic diseases, cancer, and immune-inflammatory disorders (psoriasis, arthritis). The company's drug discovery platform utilizes advanced protein structure analysis, molecular modeling, machine learning-based prediction, and comprehensive data analysis within a target-oriented approach. The atomic-level data obtained using these tools enables the creation of highly accurate molecules that determine optimal pharmacological profiles for the treatment of disease pathology.
2
Alumis
Funding: $569M
Alumis is a precision medicines company that is transforming the lives of patients living with immune-mediated diseases using a precision approach to develop oral therapies.
3
Evelo Biosciences
Funding: $397M
Evelo is pioneering therapies that modulate systemic immune response by acting on the gut-body network - monoclonal microbials. They have the potential to treat many diseases, including inflammatory disease, cancer, autoimmune disease, metabolic, neurobehavior and neuroinflammatory diseases.
4
Sudo Biosciences
Funding: $183M
Sudo Biosciences is a biopharmaceutical company committed to developing cutting-edge medications that are unmatched in their class that advances programs in multiple sclerosis and psoriasis
5
Zerigo Health
Funding: $67.4M
Clarify Medical is a developer of a handheld medical device used to treat psoriasis, eczema, and vitiligo .
6
SFA Therapeutics
Funding: $8.7M
SFA Therapeutics, LLC is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com