Top 29 Primary Care startups in USA

Mar 05, 2026
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1
Aledade
Funding: $677.9M
Aledade is a primary care physician platform that provides everything doctors need to create and run an accountable care organization.
2
Carbon Health
Funding: $622.5M
Carbon Health is a developer of a mobile-based healthcare network used to offer simple, convenient, and accessible healthcare.
3
One Medical
Funding: $532.1M
One Medical is a members-only technology platform offering an array of concierge medical services. Acquired by Amazon
4
K Health
Funding: $418.7M
K Health has built the first HIPAA compliant AI health app 100% fueled by data, empowering users worldwide to take control of their health. By working with a unique data set of over a billion health interactions, K Health is able to generate better and more accurate insights based on PLM (a.k.a. “People Like Me”), a new approach to understanding our health that looks at other people like us who have had similar experiences.
5
Oak Street Health
Funding: $405.3M
Oak Street Health is a network of primary care centers for adults on Medicare.
6
Everside Health
Funding: $329M
Everside Health is a direct primary care provider offering convenient on-site, near-site, and virtual care for its members.
7
98point6
Funding: $299.3M
98point6 combines deep technology with the expertise of board-certified physicians to provide text-based primary care anytime, anywhere.
8
Crossover Health
Funding: $281.5M
Crossover Health designs and delivers membership based primary health and secondary care services to self insured employers.
9
HarmonyCares
Funding: $200M
HarmonyCares is a home-based health care provider for adults and for those with complex medical issues.
10
UpStream
Funding: $185M
UpStream offers technology and support services for value-based primary care practices
11
CenterWell
Funding: $171.1M
Heal is startup offering house calls with primary care doctors, along with video appointments
12
Midi Health
Funding: $152M
Midi is a virtual care clinic for women that treats depression, weight problems, gynecological cancer, sexual and period problems. It provides an app for booking virtual meetings and videocalls with experts. Together with your clinician, you'll review all possible solutions—including supplements, prescription medication and lifestyle changes. Midi is available in all 50 states, with insurance coverage for virtual visits and prescriptions.
13
Harbor Health
Funding: $125.5M
Harbor Health is a multi-specialty clinic group that provides smarter health care using technology.
14
Vera Whole Health
Funding: $95.5M
Vera Whole Health delivers primary care, acute care, and health coaching via on or near-site clinics.
15
Pearl Health
Funding: $95.5M
Pearl Health helps independent primary care providers reimagine how they visualize, understand, and care for their patients.
16
Lemonaid Health
Funding: $57.5M
Lemonaid Health is a direct-to-consumer primary care platform that uses technology to change the way people interact with health care.
17
Accompany Health
Funding: $56M
Accompany Health provides comprehensive in-home care to patients who live in sometimes underserved regions.
18
KeyCare
Funding: $54.4M
KeyCare is a virtual care platform powered by Epic created to support progressive health systems.
19
Firefly Health
Funding: $52.2M
Firefly Health is a virtual-first health care company that provides primary healthcare services that redefine high-quality patient care.
20
PeopleOne Health
Funding: $44.6M
World-class treatment and prevention healthcare that also leads to significant savings for employers & employees by keeping people healthier
21
Lotus Health
Funding: $41M
Lotus Health AI is a free primary care service available 24/7 in 50 languages. It allows users to consult with AI about their health and provides real-world care, including diagnostics, prescriptions, malpractice insurance, HIPAA-compliant protection and full access to patient medical records. For urgent health issues, Lotus directs patients to the nearest urgent care center and if a physical examination is required, it refers patients to a doctor for an in-person consultation. The company has developed a proprietary AI model that analyzes latest evidence-based research with the patient's medical history and clinical data to create a treatment plan. Because AI models are prone to hallucinations, the company engages board-certified physicians from leading US medical institutions to review final diagnoses, lab orders and prescriptions.
22
Curai Health
Funding: $38.2M
Curai Health is a virtual care company that uses artificial intelligence to provide chat-based primary care at a lower cost.
23
Parsley Health
Funding: $36.1M
Parsley Health is redesigning primary care by creating boutique medical practice, integrating the latest in medical testing, technology and nutrition research.
24
Alpha Medical
Funding: $35M
Alpha Medical is a virtual primary care company focused on women’s health
25
PlushCare
Funding: $31M
PlushCare is a tech-enabled concierge primary care practice built for the modern world.
26
Juno Medical
Funding: $17.8M
Juno Medical is a whole-family healthcare platform that provides modern open-access care for an entire family’s day-to-day needs.
27
Assure Health
Funding: $11.6M
Assure Health is a virtual care and remote patient monitoring provider for patients with chronic conditions
28
Zocalo Health
Funding: $5.2M
Zócalo Health is a virtual healthcare service for Latino patients
29
Give Virtual Care
Funding: $900K
Give Virtual Care provides Best-In-Class telehealth, prescriptions & crisis care.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com