Top 8 Orthopedics startups in USA

Sep 22, 2025 | By Jason Kwon

1
Funding: $109.3M
Vori Health offers a nationwide, all-inclusive medical practice that is uniquely positioned to address back, neck, and other joint issues.
2
Funding: $95M
Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions in the inflammatory, cardiovascular, orthopedic and wound healing markets. The company operates its business through two segments: Therapeutics and Biosurgery segment. The Therapeutics segment focuses on developing biologic stem cell drug candidates from readily available and non-controversial sources. One of its products, Stromagen was used to treat breast cancer in clinical trials.
3
Funding: $50.2M
RecoveryOne is an innovator in mHealth solutions for patients recovering from orthopedic injuries.
4
Funding: $40M
Regenexx focuses on developing breakthrough non-surgical options for people suffering from various orthopedic disorders. We have developed a patent-pending procedure that uses your own stem cells and blood growth factors to regenerate bone and cartilage.
5
Funding: $35.3M
CIONIC is a technology company that builds a platform for human augmentation that powers people to transcend physical limitations.
6
Funding: $25M
CurveBeam researches, designs and manufactures cone beam CT imaging equipment for the orthopedic specialties. CurveBeam is privately owned and operated.
7
Funding: $11M
Limber is a digital home-exercise, remote monitoring, data analytics, and care navigation solution for musculoskeletal (MSK) conditions.
8
Funding: $5M
Upswing Health provides a new way to conveniently deliver orthopedic care.
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com