Top 10 Microbiome startups in USA

Updated: May 01, 2024

1
Funding: $1.6B
Ginkgo Bioworks is the organism company. We design custom microbes for customers across multiple markets. We build our foundries to scale the process of organism engineering using software and hardware automation. Organism engineers at Ginkgo learn from nature to develop new organisms that replace technology with biology.
2
Funding: $974.1M
Zymergen engineers better microbes that make useful molecules, which are part of all the materials in our daily lives. We are engineering biology predictably, reliably and to levels of performance unattainable through traditional R&D methods. Our comprehensive approach brings together technology, automation, and biology with the most sophisticated capabilities in each.
3
Funding: $537.8M
Seres Therapeutics is creating a new class of medicines to treat diseases resulting from functional deficiencies in the microbiome, a condition known as dysbiosis
4
Funding: $433.1M
Vedanta Biosciences is developing a class of drugs that work by modulating the human microbiome.
5
Funding: $397M
Evelo is pioneering therapies that modulate systemic immune response by acting on the gut-body network - monoclonal microbials. They have the potential to treat many diseases, including inflammatory disease, cancer, autoimmune disease, metabolic, neurobehavior and neuroinflammatory diseases.
6
Funding: $276M
Viome has developed technology aimed at balancing microorganisms in the gut. With Viome, you can fine-tune the function of your gut microbiome with a personalized diet to minimize the production of harmful metabolites and maximize the production of beneficial ones, so that you experience increased energy and general well-being, all while reaching and maintaining a healthy state of balance.
7
Funding: $230.9M
Kaleido BioSciences is a company working to design and analyze the microbiome system and provide adaptive solutions.
8
Funding: $188.8M
Finch Therapeutics Group is a clinical-stage biopharmaceutical company focused on developing and delivering innovative therapies that harness the human gut microbiome.
9
Funding: $115.9M
Axial Biotherapeutics is a biopharmaceutical company harnessing the link between the human gut microbiome and Central Nervous System to develop a new class of therapeutics to improve the quality of life for people with CNS diseases and disorders
10
Funding: $109.9M
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11
Funding: $42.8M
Azitra is a preclinical-stage development company using a microbiome based platform to deliver innovative, inexpensive, and sustainable treatments for skin disease.
12
Funding: $38,7m
AOBiome LLC is developing a transformative, new class of products based on Ammonia Oxidizing Bacteria (AOB) to improve skin health and prevent or treat skin and inflammatory diseases. The company’s probiotics are designed to provide cosmetic and therapeutic benefits by restoring the natural, protective balance afforded by beneficial skin microbes that have been lost due to modern living practices, including antibiotic use, soaps, and shampoos.
13
Funding: $31M
Scioto Biosciences is committed to moving the field of microbiome therapeutics forward. By enabling beneficial bacteria colonization in the gut, we believe our novel Activated Bacterial Therapeutic (ABT) delivery platform technology will revolutionize therapeutic interventions for diseases where there is erosion of the mucosal barrier.
14
Funding: $25.7M
Ritter Pharmaceuticals, Inc. develops novel therapeutic products, which modulate the human gut microbiome to treat inflammatory, gastrointestinal and metabolic diseases. We are discovering a new frontier in human gut health research by exploring the metabolic capacity of the gut microbiota and translating the functionality of prebiotic-based therapeutics into safe and effective applications that can have a meaningful impact on a patient’s health.
15
Funding: $16.4M
Astarte Medical delivers technology platforms to address critical needs and improve outcomes for high risk pregnancy and preterm birth.
16
Funding: $8.4M
Ombre is a provider of a microbiome testing kit designed to incorporate personalized probiotics and microbiome testing.
17

Kintai is a biotechnology company that advancing precision therapeutics based on enteric signaling networks in the human body.