Top 5 Men’s Health startups in USA

May 16, 2026
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By Jason Kwon
1
Legacy
Legacy
Funding: $47.2M
Legacy is a digital fertility clinic for men
2
Posterity Health
Posterity Health
Funding: $40.2M
Posterity Health educates, engaged, and encourages couples to approach the conception process together as an integrated unit.
3
Vault Health
Vault Health
Funding: $30M
Vault is an at-home healthcare practice specializing in men’s medicine
4
Creative Medical Technology Holdings
Creative Medical Technology Holdings
Funding: $3.7M
Creative Medical Technology Holdings is a clinical-stage biotechnology company focused on treating erectile dysfunction and stroke using stem cell treatments.
5
Contraline
Contraline
Funding: $24.6M
Contraline is developing the first long-lasting, reversible contraceptive for men
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  See also:
Top 11 Ultrasound startups
Top 11 Ultrasound startups
Market Landscape for Medical Startups
Market Landscape for Medical Startups
Top 10 Countries by number of Medical Startups
Top 10 Countries by number of Medical Startups
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com