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Top 32 Lung Cancer treatment startups
Oct 24, 2025 | By Jason Kwon | 16 |
These startups develop new lung cancer treatments and diagnostics technologies, such as robot-assisted surgery, targeted therapy, immunotherapy, stereotactic body radiation therapy, cryoablation, proton therapy, radiofrequency ablation.
1
Country: USA | Funding: $3.9B
At Moderna, we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells.
At Moderna, we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells.
2
Country: USA | Funding: $1.6B
IOVANCE Biotherapeutics is focused on the development and commercialization of autologous cellular immunotherapies optimizing personalized, tumor-directed Tumor Infiltrating Lymphocytes (TIL)
IOVANCE Biotherapeutics is focused on the development and commercialization of autologous cellular immunotherapies optimizing personalized, tumor-directed Tumor Infiltrating Lymphocytes (TIL)
3
Country: USA | Funding: $1.3B
Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer.
Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer.
4
Country: USA | Funding: $1.3B
Fate Therapeutics is a stem cell and developmental biology research company using biological mechanisms to develop stem cell therapeutics.
Fate Therapeutics is a stem cell and developmental biology research company using biological mechanisms to develop stem cell therapeutics.
5
Country: USA | Funding: $325M
Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
6
Country: USA | Funding: $313M
Bicara Therapeutics develops dual-action cancer therapies, combining targeted treatments with tumor modulators for enhanced impact.
Bicara Therapeutics develops dual-action cancer therapies, combining targeted treatments with tumor modulators for enhanced impact.
7
Country: USA | Funding: $177M
Antares is a biotechnology company focused on developing transformational,medicines targeting validated cancer and other serious diseases.
Antares is a biotechnology company focused on developing transformational,medicines targeting validated cancer and other serious diseases.
8
Country: Denmark | Funding: $160.4M
Galecto develops galectin modulators for the treatment of severe diseases, including fibrosis and cancer. The company builds on more than 10 years of research into galectins and galectin modulators, which combined with a strong patent estate gives Galecto Biotech a unique platform.
Galecto develops galectin modulators for the treatment of severe diseases, including fibrosis and cancer. The company builds on more than 10 years of research into galectins and galectin modulators, which combined with a strong patent estate gives Galecto Biotech a unique platform.
9
Country: USA | Funding: $112.3M
iMDx is focused on cancers with large patient populations and significant unmet need. The company is developing three genetic tests – blood tests for breast cancer and lung cancer, and a urine-based test for bladder cancer.
iMDx is focused on cancers with large patient populations and significant unmet need. The company is developing three genetic tests – blood tests for breast cancer and lung cancer, and a urine-based test for bladder cancer.
10
Country: USA | Funding: $106M
Totus Medicines is a provider of chemical biology technologies by creating life-changing covalent drugs.
Totus Medicines is a provider of chemical biology technologies by creating life-changing covalent drugs.
11
Country: China | Funding: $101.6M
Juventas is a provider and developer of innovative immune cell therapeutic drugs.
Juventas is a provider and developer of innovative immune cell therapeutic drugs.
12
Country: USA | Funding: $95M
Lantern Pharma is a clinical stage pharmaceutical company developing new classes of precision cancer drugs with novel mechanisms of action.
Lantern Pharma is a clinical stage pharmaceutical company developing new classes of precision cancer drugs with novel mechanisms of action.
13
Country: USA | Funding: $89.4M
Genprex is a clinical stage gene therapy company developing molecular therapies to better target lung cancer cells. Their new approach to treating cancer is based upon our novel proprietary technology platform, including our initial product candidate, Oncoprex immunogene therapy, or Oncoprex.
Genprex is a clinical stage gene therapy company developing molecular therapies to better target lung cancer cells. Their new approach to treating cancer is based upon our novel proprietary technology platform, including our initial product candidate, Oncoprex immunogene therapy, or Oncoprex.
14
Country: USA | Funding: $82.4M
Rain Therapeutics is a biotech company laser focused on a subtype of non-small cell lung cancer
Rain Therapeutics is a biotech company laser focused on a subtype of non-small cell lung cancer
15
Country: USA | Funding: $65M
Actuate Therapeutics is a biopharmaceutical company focused on the development of compounds for use in the treatment of cancer, and inflammatory diseases leading to fibrosis and neurodegeneration. Our work has led to some fascinating results around anti-tumor activity in the brain, pancreas, lungs, and breasts.
Actuate Therapeutics is a biopharmaceutical company focused on the development of compounds for use in the treatment of cancer, and inflammatory diseases leading to fibrosis and neurodegeneration. Our work has led to some fascinating results around anti-tumor activity in the brain, pancreas, lungs, and breasts.
16
Country: UK | Funding: $52M
Iksuda Therapeutics is a biotechnology company specializing in the development of next generation biotherapeutics
Iksuda Therapeutics is a biotechnology company specializing in the development of next generation biotherapeutics
18
Country: China | Funding: CN¥201M
12 Sigma is an innovative healthcare company with leading artificial intelligence technology and medical imaging applications.
12 Sigma is an innovative healthcare company with leading artificial intelligence technology and medical imaging applications.
19
Country: Israel | Funding: $28.5M
A medical device company specializing in augmented real-time imaging. It develops LungVision platform for planning, navigating to, and targeting small pulmonary nodules within the peripheral regions of the lungs. The product integrates into bronchoscopy suites and provides a step-by-step process that the company claims doesn’t require a large learning curve.
A medical device company specializing in augmented real-time imaging. It develops LungVision platform for planning, navigating to, and targeting small pulmonary nodules within the peripheral regions of the lungs. The product integrates into bronchoscopy suites and provides a step-by-step process that the company claims doesn’t require a large learning curve.
20
Country: UK | Funding: $15.3M
Optellum develops an imaging biomarker for smart lung cancer AI-detection.
Optellum develops an imaging biomarker for smart lung cancer AI-detection.
