Top 10 Depression treatment startups in USA

Updated: May 09, 2024

1
Funding: $462M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
2
Funding: $409M
Pear Therapeutics develops digital therapies to address a broad range of severe conditions including addiction, schizophrenia, pain, post-traumatic stress disorder, anxiety, depression, and sleep. PEAR’s eFormulationTM platform combines pharmaceutical preparations with user-friendly, customizable, and scientifically validated software applications. PEAR’s patented approach provides better outcomes for patients, smarter engagement and tracking tools for clinicians, and cost-effective solutions for payors. Pear Therapeutics filed for bankruptcy
3
Funding: $373.4M
Neuronetics has pioneered and refined the NeuroStar TMS Therapy system. This non-invasive, non-systemic treatment for depression uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions. NeuroStar TMS Therapy is a safe and effective outpatient procedure, performed in a physician's office with each treatment lasting about 37 minutes daily for four to six weeks.
4
Funding: $366.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
5
Funding: $260M
Neurocrine Biosciences engages in the discovery and development of drugs for the treatment of neurological and endocrine-related diseases.
6
Funding: $99M
Midi is a virtual care clinic for women that treats depression, gynecological cancer, and period problems.
7
Funding: $53.3M
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
8
Funding: $42.5M
Cervel Neurotech is a privately held medical device company, pioneering a non-invasive, non-pharmacologic and non-systemic treatment for psychiatric and neurologic illnesses. Cervel Neurotech is pioneering a new approach to an established technology – repetitive transcranial magnetic stimulation (rTMS) – designed to produce better outcomes and a more comfortable treatment for patients.
9
Funding: $31M
Limbix builds virtual reality to improve mental health treatment by making it more effective, efficient, and easier to access.
10
Funding: $18.4M
NeuroSigma is a life sciences company focused on bioelectronics products and commercialization of its unique Trigeminal Nerve Stimulation (TNS) technology, and has a growing pipeline of treatments targeting epilepsy, depression, attention deficit hyperactivity disorder (ADHD), post-traumatic stress disorder (PTSD), Lennox Gastaut syndrome (LGS) and traumatic brain injury (TBI).
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11
Funding: $10.5M
Sentio is a behavioral health startup offering an emotion-sensing wearable Feel that provides continuous monitoring and real-time personalized interventions for individuals that suffer from anxiety and depression.
12
Funding: $4.2M
Options MD provides personalized care for people suffering from severe and treatment-resistant mental illnesses.
13
Funding: $1M
UpLift is a comprehensive digital program for depression.