Top 6 Brain Regeneration startups in UK

Feb 10, 2026
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1
Aerska
Funding: $60M
Aerska develops RNA-based therapies to treat, slow and prevent brain diseases. The company uses blood-brain barrier drug delivery technology to deliver targeted RNA interference-based drugs to treat neurological diseases. This technology serves as a drug delivery platform that transports RNAi across the blood-brain barrier. The technology works by creating antibodies or molecules that bind to specific receptors on the surface of the blood-brain barrier. This action tricks the barrier, allowing the therapeutic agent to pass through endothelial cells and enter the brain parenchyma.
2
WaveBreak Therapeutics
Funding: $40.3M
WaveBreak Therapeutics is a biopharmaceutical company based, focused on drug discovery and development for protein misfolding diseases.
3
Oxford Endovascular
Funding: $28.4M
Oxford Endovascular are developing a novel treatment for treating brain aneurysms.
4
Magstim
Magstim has always been at the cutting edge of the evolution of transcranial magnetic stimulation (TMS) from its conception as a valuable research tool to its coming of age as a revolutionary treatment for nerve and brain disorders such as major depressive disorder (MDD).
5
Shift Bioscience
Funding: £12.5M
Shift Bioscience is creating new drug targets and diagnostic tools to enhance healthy lifespan through the repair of mitochondrial genes that cause neurodegenerative diseases or coronary heart disease.
6
Avalon AI
Funding: $120K
We use Machine learning to automatically derive accurate brain features (e.g. the volume of the hippocampus) from brain scans and compare them to a normative population. We also provide handy 2D and 3D visualisations of brain features. This not only saves time to neuroradiologists but also empowers them to make highly accurate reports, by using the latest techniques and findings in neurosciences
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Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com