Top 115 medical and healthcare startups in London
Apr 24, 2026
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17
1
Funding: $50M
Enara Bio develops targeted cancer immunotherapies using its Dark Antigen discovery engine and optimized T-cell activator platform. Dark Antigens cluster - is a rich source of novel cancer targets derived from genomic regions previously considered "dark" or non-coding. The EDAPT platform helps to identify these dark targets. The company has also developed EnTiCE platform for creating bispecific T-cell activators against these identified targets to improve treatment outcomes for a wide range of cancer patients. Enara Bio's pipeline includes clinical trials against solid tumors, non-small cell lung cancer, melanoma, and ovarian cancer. The startup is backed by leading biotech investors, including RA Capital, Pfizer Ventures, M Ventures, Samsara BioCapital, and SV Health Investors.
Enara Bio develops targeted cancer immunotherapies using its Dark Antigen discovery engine and optimized T-cell activator platform. Dark Antigens cluster - is a rich source of novel cancer targets derived from genomic regions previously considered "dark" or non-coding. The EDAPT platform helps to identify these dark targets. The company has also developed EnTiCE platform for creating bispecific T-cell activators against these identified targets to improve treatment outcomes for a wide range of cancer patients. Enara Bio's pipeline includes clinical trials against solid tumors, non-small cell lung cancer, melanoma, and ovarian cancer. The startup is backed by leading biotech investors, including RA Capital, Pfizer Ventures, M Ventures, Samsara BioCapital, and SV Health Investors.
2
Funding: $1.1B
Autolus uses advanced CAR-T cell therapy to treat hematological malignancies and solid tumors. While CAR T-cell therapy has revolutionized cancer treatment, it can also cause significant immunotoxicity. Autolus has developed a novel CAR-construct with rapid binding kinetics that is similar to natural T cells and provides improved tolerability in patients with certain types of leukemia. Furthermore, Autolus addresses the issue of immunotoxicity through a personalized dosing approach. The company is also seeking to adopt CAR-T therapy to patients with acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, T-cell lymphoma and solid tumors. It is supporting several ongoing CAR-T clinical trials that are opening up new treatment options and offering new hope for these patients.
Autolus uses advanced CAR-T cell therapy to treat hematological malignancies and solid tumors. While CAR T-cell therapy has revolutionized cancer treatment, it can also cause significant immunotoxicity. Autolus has developed a novel CAR-construct with rapid binding kinetics that is similar to natural T cells and provides improved tolerability in patients with certain types of leukemia. Furthermore, Autolus addresses the issue of immunotoxicity through a personalized dosing approach. The company is also seeking to adopt CAR-T therapy to patients with acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia, T-cell lymphoma and solid tumors. It is supporting several ongoing CAR-T clinical trials that are opening up new treatment options and offering new hope for these patients.
3
Funding: $601.7M
Isomorphic Labs provides AI-driven solutions for drug discovery and development.
Isomorphic Labs provides AI-driven solutions for drug discovery and development.
4
Funding: $430M
HOLOGEN AI develops breakthrough technologies that deliver interventional intelligence in healthcare, improving the understanding, design, evaluation, and delivery of treatments.
HOLOGEN AI develops breakthrough technologies that deliver interventional intelligence in healthcare, improving the understanding, design, evaluation, and delivery of treatments.
5
Funding: $365.1M
Beacon Therapeutics is an ophthalmic gene therapy company to treat blinding retinal illnesses and restore and enhance eyesight.
Beacon Therapeutics is an ophthalmic gene therapy company to treat blinding retinal illnesses and restore and enhance eyesight.
6
Funding: $322.6M
Medopad connects patients and providers in real time. It also collects data through wearables and lets patients send their data to healthcare professionals. The platform also offers providers and insurers ways to analyze large amounts of data using artificial intelligence and machine learning.
Medopad connects patients and providers in real time. It also collects data through wearables and lets patients send their data to healthcare professionals. The platform also offers providers and insurers ways to analyze large amounts of data using artificial intelligence and machine learning.
7
Funding: $322.6M
Huma offers a health platform used for remote patient monitoring and biological data gathering for preventative healthcare.
Huma offers a health platform used for remote patient monitoring and biological data gathering for preventative healthcare.
8
Funding: $292M
A leading British artificial intelligence company located in the knowledge quarter of London with a focus in health and drug development
A leading British artificial intelligence company located in the knowledge quarter of London with a focus in health and drug development
9
Funding: $275.8M
Flo Health is a developer of Flo, the fastest growing AI-driven women’s health product that encompasses solutions for girls and women at every stage of their life (start of menstruation, cycle tracking, preparation for conception, pregnancy, early motherhood, menopause).
Flo Health is a developer of Flo, the fastest growing AI-driven women’s health product that encompasses solutions for girls and women at every stage of their life (start of menstruation, cycle tracking, preparation for conception, pregnancy, early motherhood, menopause).
11
Funding: $213M
Achilles Tx's mission is to develop next-generation, patient-specific therapies that harness the immune system to destroy cancer cells
Achilles Tx's mission is to develop next-generation, patient-specific therapies that harness the immune system to destroy cancer cells
12
Funding: $206.6M
YuLife is a provider of life insurance and policies providing income in the event of critical illness.
YuLife is a provider of life insurance and policies providing income in the event of critical illness.
13
Funding: $205.5M
Pulmocide develops inhaled medications for the treatment of viral and fungal respiratory tract infections. The company's lead drug, opelconazole, is in Phase 3 clinical trials for the treatment of patients with invasive pulmonary aspergillosis. Aspergillus is a genus of fungi whose spores are airborne and can cause severe, often life-threatening, lung disease in people with weakened immune systems or pre-existing lung conditions. Opelconazole has received several FDA approvals that may expedite its development and/or review, including orphan drug designation, fast-track designation, and qualified infectious disease product (QIDP) designation. It has also received orphan drug designation in the European Union.
Pulmocide develops inhaled medications for the treatment of viral and fungal respiratory tract infections. The company's lead drug, opelconazole, is in Phase 3 clinical trials for the treatment of patients with invasive pulmonary aspergillosis. Aspergillus is a genus of fungi whose spores are airborne and can cause severe, often life-threatening, lung disease in people with weakened immune systems or pre-existing lung conditions. Opelconazole has received several FDA approvals that may expedite its development and/or review, including orphan drug designation, fast-track designation, and qualified infectious disease product (QIDP) designation. It has also received orphan drug designation in the European Union.
15
Funding: $188M
Pheon Therapeutics is developing a portfolio of next-generation ADCs with the potential to treat difficult-to-treat solid tumors. Recognizing that there is no one-size-fits-all solution in ADC development, Pheon takes an adaptive approach to ADC development. Using monoclonal antibodies (mAbs) against both novel and clinically proven ADC targets and equipping them with either proprietary platform active substances with a novel mechanism of action or pre-existing linker combinations, Pheon precisely ensures the balance of safety and efficacy for each target. Pheon has assembled a world-class leadership team with two decades of ADC experience. The company is currently conducting Phase I clinical trials of its lead asset, which has demonstrated robust preclinical data, including in vivo efficacy, NHP safety and extensive expression profiling in tumors and healthy tissue.
Pheon Therapeutics is developing a portfolio of next-generation ADCs with the potential to treat difficult-to-treat solid tumors. Recognizing that there is no one-size-fits-all solution in ADC development, Pheon takes an adaptive approach to ADC development. Using monoclonal antibodies (mAbs) against both novel and clinically proven ADC targets and equipping them with either proprietary platform active substances with a novel mechanism of action or pre-existing linker combinations, Pheon precisely ensures the balance of safety and efficacy for each target. Pheon has assembled a world-class leadership team with two decades of ADC experience. The company is currently conducting Phase I clinical trials of its lead asset, which has demonstrated robust preclinical data, including in vivo efficacy, NHP safety and extensive expression profiling in tumors and healthy tissue.
16
Funding: $162.7M
CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
17
Funding: £125M
Purespring Therapeutics is an AAV gene therapy company focused on the kidney globally.
Purespring Therapeutics is an AAV gene therapy company focused on the kidney globally.
19
Funding: $130.7M
Numan is a startup which aims to tackle your tackle problem erectile dysfunction.
Numan is a startup which aims to tackle your tackle problem erectile dysfunction.
20
Funding: $118M
Proximie is a secure software solution that expands virtual surgical collaboration enabling surgeons to share expertise through AR.
Proximie is a secure software solution that expands virtual surgical collaboration enabling surgeons to share expertise through AR.
21
Funding: $100M
Vicebio is committed to employing the Molecular Clamp Technology to create vaccines against next-generation respiratory viruses.
Vicebio is committed to employing the Molecular Clamp Technology to create vaccines against next-generation respiratory viruses.
22
Funding: $98.1M
Unmind is a B2B mental health platform providing clinically-backed tools and training.
Unmind is a B2B mental health platform providing clinically-backed tools and training.
23
Funding: $93M
Causaly develops a biomedical research discovery tool designed to find and unlock key hidden evidence in biomedicine.
Causaly develops a biomedical research discovery tool designed to find and unlock key hidden evidence in biomedicine.
24
Funding: $91.1M
Touch Surgery is an interactive mobile surgical simulator that guides you step-by-step through every part of an operation, and every decision that’s made along the way.
Touch Surgery is an interactive mobile surgical simulator that guides you step-by-step through every part of an operation, and every decision that’s made along the way.
25
Funding: $89.5M
Minatx is a therapeutics company uses gene activation mechanisms to discover new medical treatments.
Minatx is a therapeutics company uses gene activation mechanisms to discover new medical treatments.
26
Funding: $89.9M
Lumeon is a digital health company that provides care pathway management solutions to the healthcare industry.
Lumeon is a digital health company that provides care pathway management solutions to the healthcare industry.
27
Funding: $81M
Synthace provides R&D cloud platform which supports scientists to share and access progress with the development of biopharmaceutical therapeutics
Synthace provides R&D cloud platform which supports scientists to share and access progress with the development of biopharmaceutical therapeutics
28
Funding: $79.5M
Lindus Health is a next-gen CRO running clinical trials for the health and biotech sectors.
Lindus Health is a next-gen CRO running clinical trials for the health and biotech sectors.
29
Funding: $77.5M
R1 Therapeutics is a clinical-stage biopharmaceutical business that develops first-in-class treatments for kidney disease patients.
R1 Therapeutics is a clinical-stage biopharmaceutical business that develops first-in-class treatments for kidney disease patients.
30
Funding: $73.1M
Harnessing the power of machine learning to create better protein therapeutics.
Harnessing the power of machine learning to create better protein therapeutics.
31
Funding: $71.6M
Doccla is a healthtech startup with a platform that can monitor patients on hospital wards and in the home
Doccla is a healthtech startup with a platform that can monitor patients on hospital wards and in the home
32
Funding: $70.6M
Lifebit is building the world’s first intelligent genomics platform that understands DNA data and generates meaningful insights like humans do.
Lifebit is building the world’s first intelligent genomics platform that understands DNA data and generates meaningful insights like humans do.
33
Funding: $70M
Elevara is a clinical-stage firm working on innovative therapies to treat rheumatoid arthritis and other chronic inflammatory disorders.
Elevara is a clinical-stage firm working on innovative therapies to treat rheumatoid arthritis and other chronic inflammatory disorders.
34
Funding: $67.3M
Your.MD is the world’s smartest AI health information service, offering everyone free access to the health information they need. Your.MD empowers people to discover what’s wrong with them thanks to the world’s first AI system designed to understand individual situations and personal factors, receive medically certified guidance (in partnership with the UK’s NHS)
Your.MD is the world’s smartest AI health information service, offering everyone free access to the health information they need. Your.MD empowers people to discover what’s wrong with them thanks to the world’s first AI system designed to understand individual situations and personal factors, receive medically certified guidance (in partnership with the UK’s NHS)
37
Funding: $58M
Signifier Medical Technologies is a medical technology company
Signifier Medical Technologies is a medical technology company
38
Funding: $56.7M
Peppy develops employee healthcare benefits platform focusing on family support, female health and mental well-being
Peppy develops employee healthcare benefits platform focusing on family support, female health and mental well-being
39
Funding: £40M
Adendra Therapeutics wants to use new insights into dendritic cell biology to develop a novel type of immunotherapy.
Adendra Therapeutics wants to use new insights into dendritic cell biology to develop a novel type of immunotherapy.
41
Funding: $50M
SheMed is transforming women's health by offering accessible and personalized test-to-treat solutions designed particularly for women.
SheMed is transforming women's health by offering accessible and personalized test-to-treat solutions designed particularly for women.
42
Funding: $50M
Encord’s DICOM tool is a truly optimized medical imaging tool built specifically for radiologists, with full 3D views, native windowing functionality and AI-powered automation features. It allows to annotate DICOM imagery at scale including CT, X-ray, MRI and ultrasound.
Encord’s DICOM tool is a truly optimized medical imaging tool built specifically for radiologists, with full 3D views, native windowing functionality and AI-powered automation features. It allows to annotate DICOM imagery at scale including CT, X-ray, MRI and ultrasound.
44
Funding: $45.3M
Florence is an online marketplace that connects vacant care home shifts to local nurses and carers looking for extra work
Florence is an online marketplace that connects vacant care home shifts to local nurses and carers looking for extra work
45
Funding: £28.7M
uMotif is a patient-facing clinical trial software company. Through simple and engaging web and mobile apps, people track and monitor their health and choose to share their data with their clinicians, carers, friends and family members to improve care.
uMotif is a patient-facing clinical trial software company. Through simple and engaging web and mobile apps, people track and monitor their health and choose to share their data with their clinicians, carers, friends and family members to improve care.
46
Funding: $35.7M
Urban lets you book a growing range of wellness services on-demand — now including massage, osteopathy, facial, and nail services
Urban lets you book a growing range of wellness services on-demand — now including massage, osteopathy, facial, and nail services
47
Funding: £27.7M
Patchwork is a health tech start up providing software solutions in attempt to solve temporary staffing challenges.
Patchwork is a health tech start up providing software solutions in attempt to solve temporary staffing challenges.
49
Funding: $31.3M
HelloSelf is a health and wellness platform that provides its users with digital access to therapists.
HelloSelf is a health and wellness platform that provides its users with digital access to therapists.
50
Funding: $31M
Tympa offers a portable system that uses a smartphone for hearing health assessments. The company pitches the device as a way for clinics and community-based providers to capture high-definition images of the inside of patients' ears, remove wax and conduct hearing assessments.
Tympa offers a portable system that uses a smartphone for hearing health assessments. The company pitches the device as a way for clinics and community-based providers to capture high-definition images of the inside of patients' ears, remove wax and conduct hearing assessments.
