Top 72 medical and healthcare startups in Canada

Dec 22, 2025
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1
Profound Medical
Funding: $326.2M
Profound Medical manufactures a device for MRI-guided transurethral ultrasound ablation of the prostate cancer. TULSA-PRO is an FDA/CE-cleared surgical robot for ablation in men with localized prostate cancer, associated with obstructive benign prostatic hyperplasia (BPH), localized recurrent prostate cancer after radiation therapy or large-volume BPH. The system enables preoperative surgical planning, 360-degree guidance, precise and accurate targeting, automatic energy adjustment and real-time temperature monitoring.
2
dentalcorp
Funding: $1.1B
dentalcorp is Canada's largest network of dentists and dental practices.
3
AbCellera Biologics
Funding: $887M
AbCellera Biologics offers development of antibody therapeutics to improve patient outcomes.
4
Milestone Pharmaceuticals
Funding: $360.9M
Milestone Pharmaceuticals is a drug development company developing small molecule therapeutics for the treatment of cardiovascular diseases.
5
AlayaCare
Funding: $293.4M
AlayaCare delivers an end-to-end home health care software platform and hardware ecosystem for patients.
6
League
Funding: $271.1M
League is a digital health platform that connects people to a comprehensive network of health services and benefits.
7
Fullscript
Funding: $267M
Fullscript is a supplement dispensing platform and patient adherence tool that supports practitioners at the point of care and beyond.
8
Alpha-9 Oncology
Funding: $259M
Alpha9 Theranostics is a biopharma company that focuses on radiotherapeutics for the treatment of solid and hematologic malignancies.
9
Repare Therapeutics
Funding: $251.7M
Repare is developing new, precision oncology drugs for patients that target specific vulnerabilities of tumor cells.
10
Deep Genomics
Funding: $236.7M
Deep Genomics brings together world-leading expertise in machine learning and genome biology. We’re inventing a new generation of computational technologies that predict what will happen within a cell when DNA is altered by genetic variation, whether natural or therapeutic. Our systems predict the molecular effects of genetic variation, opening a new and exciting path to discovery for disease diagnostics and therapies.
11
BlueRock Therapeutics
Funding: $225M
BlueRock Therapeutics is pioneering cell therapies that replace dead, damaged, or dysfunctional cells to restore critical natural functions in the body. The company is initially targeting severe brain and heart conditions, two areas of critical unmet medical need with blockbuster potential.
12
Aspect Biosystems
Funding: $196.1M
Aspect Biosystems is an award-winning biotechnology company specializing in 3D bioprinting and tissue engineering. We bring together a multi-talented team of individuals to develop cutting-edge custom human tissue technology for use in the life sciences.
13
Abdera Therapeutics
Funding: $148.3M
Abdera is an oncology company developing targeted alpha therapies (TATs) for patients with relapsed, refractory, and metastatic cancers.
14
Reunion Neuroscience
Funding: $133M
Reunion Neuroscience is a clinical-stage pharmaceutical company developing therapeutic solutions for underserved mental health conditions.
15
Oncolytics Biotech
Funding: $120.1M
Oncolytics Biotech is developing REOLYSIN®, a safe and well-tolerated intravenously delivered immuno-oncolytic virus (IOV) that targets cancer through a unique mechanism of action with two components, selective tumor lysis and activation of the innate and adaptive immune systems, creating an inflamed phenotype to treat a variety of solid tumors and hematological malignancies.
16
Congruence Therapeutics
Funding: $101.6M
Congruence Therapeutics is building a team of 'drug hunters' to go after rare disease targets
17
Felix Health
Funding: $76.8M
Felix is a digital healthcare company providing seamless access to medication through online diagnoses and delivery.
18
Maple
Funding: $71.7M
Maple's mission is to tackle some of the world’s most meaningful issues in healthcare, starting with timely and convenient access to doctors and other healthcare providers – so that you can feel better, faster.
19
Smile CDR
Funding: $65M
Smile CDR makes it easy for healthcare stakeholders to collect and exchange data with our leading FHIR-based data liberation platform.
20
Swift Medical
Funding: $56.1M
Swift Medical develops an app that is able to capture wound care information by waving the smartphone above the injured site in a wand-like fashion.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com