Top 167 Mental Health startups

Updated: Mar 06, 2026
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These startups develop new Mental Health technologies, like telemedicine apps, virtual reality systems for rehabilitation, mental health management apps, electromagnetic brain stimulation...
1
Grow Therapy
Country: USA | Funding: $328M
Grow Therapy helps therapists easily start and grow thriving insurance-accepting practices, giving them the administrative and business tools, peer community support, and pipeline of referrals they need to make their lives better.
2
Talkiatry
Country: USA | Funding: $452M
Talkiatry is a virtual mental health care platform with over 800 full-time psychiatrists. These specialists provide care for a variety of conditions, including anxiety, depression, insomnia, mood disorders, postpartum depression, pediatric mental health, bipolar disorder, OCD, PTSD and substance use disorders. Their work is powered by AI platform that facilitates interaction with patients between visits and monitors the quality and level of care provided. The startup also implements innovative payment models with insurance companies.
3
Click Therapeutics
Country: USA | Funding: $1B
Click Therapeutics is looking to boost work on an online platform of “prescription digital therapeutics.” The company’s leading product is Clickotine, deisgned for smoking cessation, that works as a phone app designed to help people stop smoking using input from Magellan Health, a behavioral healthcare company.
4
Lyra Health
Country: USA | Funding: $910.1M
Lyra is transforming mental health care by creating a frictionless experience for members, providers, and employers. Using technology and data, we connect companies and their employees to mental health providers and treatments that work.
5
Cerebral
Country: USA | Funding: $487M
Cerebral is a mission-driven telemedicine company that provides affordable, efficient access to treatment for anxiety, depression and insomnia.
6
Spring Health
Country: USA | Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
7
Neuronetics
Country: USA | Funding: $451.4M
Neuronetics has pioneered and refined the NeuroStar TMS Therapy system. This non-invasive, non-systemic treatment for depression uses a highly focused, pulsed magnetic field to stimulate function in targeted brain regions. NeuroStar TMS Therapy is a safe and effective outpatient procedure, performed in a physician's office with each treatment lasting about 37 minutes daily for four to six weeks.
8
Compass Pathways
Country: UK | Funding: $421.2M
COMPASS Pathways is advancing the drug, the active ingredient in magic mushrooms, for use in people with treatment-resistant depression.
9
Talkspace
Country: USA | Funding: $413.7M
Talkspace is an online therapy startup that offers affordable and confidential therapy with network of professional and licensed therapists.
10
Headway
Country: USA | Funding: $325.5M
Headway is building a new mental healthcare system that everyone can access.
11
Quartet Health
Country: USA | Funding: $270.9M
Quartet is a technology company improving behavioral health delivery for patients, providers, and payers.
12
Alma
Country: USA | Funding: $220.5M
Alma is a membership-based network for mental health care providers.
13
Brightline
Country: USA | Funding: $219M
Brightline is a med-tech company that provides behavioral healthcare services for children and their families.
14
Calm
Country: USA | Funding: $218M
Calm is working to bring the amazing benefits of meditation to a busy world. Calm operates an online portal which allows busy and information loaded web workers to reduce stress.
15
Cognito Therapeutics
Country: USA | Funding: $216.8M
Cognito is developing a therapeutic device, Spectris, which can be prescribed by doctors and used by patients at home to treat Alzheimer's disease by stimulating coordinated neural activity through non-invasive visual and auditory stimulation. The device is designed as a full-size headphones. The pivotal clinical study, which is evaluating Spectris AD therapy for Alzheimer's disease, is currently underway, and the company is preparing to submit an application to the FDA.
16
Lark Health
Country: USA | Funding: $195.7M
Lark Health develops AI-based chronic disease management platform for diabetes, hyper tension and behavioral health.
17
SonderMind
Country: USA | Funding: $183M
SonderMind Wellness Centers is a franchisor of community centers for behavioral health providers.
18
Modern Health
Country: USA | Funding: $167.4M
Modern Health is a mental well-being platform for innovative companies that want to reduce burnout and prevent turnover.
19
Big Health
Country: USA | Funding: $135.1M
Big Health operates a digital healthcare portal used to offer behavioral programs for mental health issues.
20
Eleos
Country: USA | Funding: $128M
Eleos Health is a mental health startup that focuses on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
21
Eleos Health
Country: USA | Funding: $128M
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
22
Woebot Health
Country: USA | Funding: $123.3M
Woebot Health offers digital therapeutics to make mental health radically accessible.
23
Happify Health
Country: USA | Funding: $118.7M
Happify is a software-enabled health care platform designed to improve mental and physical health.
24
Author Health
Country: USA | Funding: $115M
Author Health provides care and treatment for Medicare Advantage recipients with substance use disorders and serious mental illness.
25
Valera Health
Country: USA | Funding: $115M
Valera Health is a tech-enabled mental health company delivering inclusive, comprehensive and tailored care.
26
Brightside Health
Country: USA | Funding: $114.4M
Brightside Health is a telemedicine platform integrating precision psychiatry with advanced therapeutic techniques.
27
Holmusk
Country: Singapore | Funding: $106.2M
Holmusk is a data science and health technology company that aims to reverse chronic disease and behavioral health issues. The company develops innovative, scalable and cost-effective digital disease management programs to help patients improve their health.
28
Two Chairs
Country: USA | Funding: $102M
Two Chairs is rebuilding the nation's mental health system. With expert clinicians, thoughtful technology, and user-centric design they’re making exceptional mental healthcare available to everyone.
29
Unmind
Country: UK | Funding: $98.1M
Unmind is a B2B mental health platform providing clinically-backed tools and training.
30
Octave
Country: USA | Funding: $91M
Octave offers a modern practice that brings a primary care approach to serve the mental health needs of young urban professionals.
31
NOCD
Country: USA | Funding: $84M
nOCD offers a mobile mental health app. Our goal is to revolutionize OCD treatment.
32
ieso
Country: UK | Funding: $77.9M
Transforming mental healthcare, by unlocking the power of clinical data
33
eNeura
Country: USA | Funding: $75.8M
eNeura, a privately held medical technology company, is pioneering the use of portable, non-invasive Transcranial Magnetic Stimulation (TMS) devices for treatment of migraine. Prescribed by physicians but designed for patient use, it is the first truly portable, convenient TMS product that will allow migraine patients to administer treatment as needed—at home, in the office or on the go.
34
aptihealth
Country: USA | Funding: $65M
Aptihealth specializes in behavioral health, health plans, primary care, therapy, direct messaging and medication management services.
35
NeuroFlow
Country: USA | Funding: $60.6M
NeuroFlow is a HIPAA-compliant cloud-based platform that empowers health care providers to objectively track, assess, and engage patients using evidence-based practices to support their mental health.
36
Folx Health
Country: USA | Funding: $59.4M
Folx Health is a telehealth platform that provides digital healthcare services designed for the LGBTQIA+ community.
37
Concert Health
Country: USA | Funding: $58.5M
Concert Health offers behavioral health services to primary care practices
38
Osmind
Country: USA | Funding: $57.2M
Osmind is the premier technology platform for breakthough mental health treatment and research.
39
Rippl
Country: USA | Funding: $55M
Rippl, a mental health organization, is committed to assisting seniors who suffer from dementia and other neurocognitive disorders.
40
Meru Health
Country: USA | Funding: $53.3M
Meru Health offers a digital program that helps improve the lives of people living with depression and saves on healthcare costs.
41
Real 
Country: USA | Funding: $53M
Real is making mental wellness an essential part of wellbeing.
42
Brave Health
Country: USA | Funding: $50M
Brave Health is an online platform that offers therapy and medication management for psychiatric conditions to improve mental health.
43
Array Behavioral Care
Country: USA | Funding: $49M
Array Behavioral Care telepsychiatry service provider with a mission to transform access to quality and timely behavioral health care.
44
Koa Health
Country: Spain | Funding: €44.1M
Koa Health is a digital wellbeing and therapeutics solutions combine the latest clinical research and breakthrough technologies.
45
BrainCheck
Country: USA | Funding: $41.2M
BrainCheck is a mobile interactive test for cognitive health.
46
Sonde Health
Country: USA | Funding: $41.3M
Sonde Health has developed a technology that uses voice biomarkers to identify a number of diseases such as respiratory disorders and mental illness.
47
Iris Telehealth
Country: USA | Funding: $40M
Iris Telehealth is a leading provider of telepsychiatry services for community mental health centers, community health centers.
48
Uwill
Country: USA | Funding: $38.5M
Uwill with colleges to offer students on-demand virtual access to licensed therapists and providers trained in crisis counseling. Students can also attend online wellness events through the company's mental health-and-wellness app.
49
Nirvana Health
Country: USA | Funding: $39.4M
Nirvana Health is a mental health company providing modern fintech and insurance solutions to healthchare.
50
Little Otter
Country: USA | Funding: $35.7M
Little Otter is a children's mental health company that developed an app that focuses on the mental health of children and their families.
Jason Kwon
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com